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Volumn 95, Issue 2, 2014, Pages 133-135

In vitro prediction of clinical drug interactions with cyp3a substrates: We are not there yet

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P-450 CYP3A; DRUG INTERACTIONS; DRUGS, INVESTIGATIONAL; HUMANS;

EID: 84893796916     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2013.230     Document Type: Review
Times cited : (14)

References (11)
  • 2
    • 0025871397 scopus 로고
    • Glucuronidation of 3-azido-3-deoxythymidine catalyzed by human liver UDP-glucuronosyltransferase.Significance of nucleoside hydrophobicity and inhibition by xenobiotics
    • Resetar, A., Minick, D. & Spector, T. Glucuronidation of 3-azido-3-deoxythymidine catalyzed by human liver UDP-glucuronosyltransferase. Significance of nucleoside hydrophobicity and inhibition by xenobiotics. Biochem. Pharmacol. 42, 559-568 (1991).
    • (1991) Biochem. Pharmacol , vol.42 , pp. 559-568
    • Resetar, A.1    Minick, D.2    Spector, T.3
  • 3
    • 0026677681 scopus 로고
    • The rational selection of drug interaction studies: Implications of recent advances in drug metabolism
    • Tucker, G.T. The rational selection of drug interaction studies: Implications of recent advances in drug metabolism. Int. J. Clin. Pharmacol. Ther. Toxicol. 30, 550-553 (1992).
    • (1992) Int. J. Clin. Pharmacol. Ther. Toxicol , vol.30 , pp. 550-553
    • Tucker, G.T.1
  • 7
    • 84858850731 scopus 로고    scopus 로고
    • Clinical drug interactions due to metabolic inhibition: Prediction, assessment, and interpretation
    • (eds. Lu, C. & Li, A.P.) John Wiley & Sons, Hoboken, NJ
    • von Moltke, L.L. & Greenblatt, D.J. Clinical drug interactions due to metabolic inhibition: Prediction, assessment, and interpretation. In Enzyme Inhibition in Drug Discovery and Development (eds. Lu, C. & Li, A.P.) 533-547 (John Wiley & Sons, Hoboken, NJ, 2010).
    • (2010) Enzyme Inhibition in Drug Discovery and Development , pp. 533-547
    • Von Moltke, L.L.1    Greenblatt, D.J.2
  • 10
    • 84893740148 scopus 로고    scopus 로고
    • Evaluation of various static in vitro-in vivo extrapolation models for risk assessment of the CYP3A inhibition potential of an investigational drug
    • Vieira, M.d.L.T. et al. Evaluation of various static in vitro-in vivo extrapolation models for risk assessment of the CYP3A inhibition potential of an investigational drug. Clin. Pharmacol. Ther. 95, 189-198 (2014).
    • (2014) Clin. Pharmacol. Ther , vol.95 , pp. 189-198
    • Vieira, M.D.L.T.1
  • 11
    • 84893723325 scopus 로고    scopus 로고
    • Evaluation of various static and dynamic modeling methods to predict clinical CYP3A induction using in vitro CYP3A4 mRNA induction data
    • Einolf, H.J. et al. Evaluation of various static and dynamic modeling methods to predict clinical CYP3A induction using in vitro CYP3A4 mRNA induction data. Clin. Pharmacol. Ther. 95, 179-188 (2014).
    • (2014) Clin. Pharmacol. Ther , vol.95 , pp. 179-188
    • Einolf, H.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.