The role of a low-dose ketamine-midazolam regimen in the management of severe painful crisis in patients with sickle cell disease

Journal of Pain and Symptom Management

Volumn 47, Issue 2, 2014, Pages 334-340

  Tawfic, Qutaiba A ^a   Faris, Ali S ^a   Kausalya, Rajini ^b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b SULTAN QABOOS UNIVERSITY HOSPITAL   (Oman)

Author keywords

ketamine; midazolam; pain management; painful crisis; Sickle cell disease

Indexed keywords

ANALGESIC AGENT; DRUG COMBINATION; HYPNOTIC SEDATIVE AGENT; KETAMINE; MIDAZOLAM; MORPHINE; NARCOTIC ANALGESIC AGENT;

ADOLESCENT; ADULT; ANALGESIA; DRUG COMBINATION; FEMALE; HUMAN; INTENSIVE CARE; INTRAVENOUS DRUG ADMINISTRATION; MALE; PAIN; PAIN MEASUREMENT; PATHOPHYSIOLOGY; PROCEDURES; RETROSPECTIVE STUDY; SICKLE CELL ANEMIA; TREATMENT OUTCOME; YOUNG ADULT;

ADMINISTRATION, INTRAVENOUS; ADOLESCENT; ADULT; ANALGESICS; ANALGESICS, OPIOID; ANEMIA, SICKLE CELL; DRUG COMBINATIONS; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; INTENSIVE CARE; KETAMINE; MALE; MIDAZOLAM; MORPHINE; PAIN; PAIN MANAGEMENT; PAIN MEASUREMENT; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84893781764     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2013.03.012     Document Type: Article

References (24)

1. S.K. Ballas Pain management of sickle cell disease Hematol Oncol Clin North Am 19 2005 785 802
2. S.K. Ballas Update on pain management in sickle cell disease Hemoglobin 35 2011 520 529
3. P. Niscola, F. Sorrentino, L. Scaramucci, P. de Fabritiis, and P. Cianciulli Pain syndromes in sickle cell disease: an update Pain Med 10 2009 470 480
4. K.M. Gil, D.A. Williams, R.J. Thompson Jr., and T.R. Kinney Sickle cell disease in children and adolescents: the relation of child and parent pain coping strategies to adjustment J Pediatr Psychol 16 1991 643 663
5. S.K. Ballas Effect of alpha-globin genotype on the pathophysiology of sickle cell disease Pediatr Pathol Mol Med 20 2001 107 121
6. S.A. Mousa, A. Al Momen, and F. Al Sayegh et al. Management of painful vaso-occlusive crisis of sickle-cell anemia: consensus opinion Clin Appl Thromb Hemost 16 2010 365 376
7. P.L. Kavanagh, P.G. Sprinz, S.R. Vinci, H. Bauchner, and C.J. Wang Management of children with sickle cell disease: a comprehensive review of the literature Pediatrics 128 2011 e1552 e1574
8. R.J. Dunlop, and K.C. Bennett Pain management for sickle cell disease Cochrane Database Syst Rev 2 2006 CD003350
9. J. Howard, V.J. Thomas, and H.M. Rawle Pain management and quality of life in sickle cell disease Expert Rev Pharmacoecon Outcomes Res 9 2009 347 352
10. S.K. Ballas Current issues in sickle cell pain and its management Hematology Am Soc Hematol Educ Program 2007 97 105
11. S.K. Ballas, R.L. Bauserman, and W.F. McCarthy et al. Hydroxyurea and acute painful crises in sickle cell anemia: effects on hospital length of stay and opioid utilization during hospitalization, outpatient acute care contacts, and at home J Pain Symptom Manage 40 2010 870 882
12. J. Wright, and S.H. Ahmedzai The management of painful crisis in sickle cell disease Curr Opin Support Palliat Care 4 2010 97 106
13. I.D. Buchanan, M. Woodward, and G.W. Reed Opioid selection during sickle cell pain crisis and its impact on the development of acute chest syndrome Pediatr Blood Cancer 45 2005 716 724
14. E.J. van Beers, C.F.J. van Tuijn, and P.T. Nieuwkerk et al. Patient-controlled analgesia versus continuous infusion of morphine during vaso-occlusive crisis in sickle cell disease, a randomized controlled trial Am J Hematol 82 2007 955 960
15. K. Gandhi, J.W. Heitz, and E.R. Viscusi Challenges in acute pain management Anesthesiol Clin 29 2011 291 309
16. M. Suzuki, K. Tsueda, and P.S. Lansing et al. Small-dose ketamine enhances morphine-induced analgesia after outpatient surgery Anesth Analg 89 1999 98 103
17. W.T. Zempsky, K.A. Loiselle, J.M. Corsi, and J.N. Hagstrom Use of low-dose ketamine infusion for pediatric patients with sickle cell disease-related pain: a case series Clin J Pain 26 2010 163 167
18. K. Subramaniam, B. Subramaniam, and R.A. Steinbrook Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review Anesth Analg 99 2004 482 495
19. C.G. Meals, B.D. Mullican, C.M. Shaffer, P.F. Dangerfield, and R.P. Ramirez Ketamine infusion for sickle cell crisis pain in an adult J Pain Symptom Manage 42 2011 e7 e9
20. N. Elia, and M.R. Tramèr Ketamine and postoperative pain - a quantitative systematic review of randomised trials Pain 113 2005 61 70
21. X.M. Deng, W.J. Xiao, M.P. Luo, G.Z. Tang, and K.L. Xu The use of midazolam and small-dose ketamine for sedation and analgesia during local anesthesia Anesth Analg 93 2001 1174 1177
22. C. Wille-Ledon, H. Chappuy, C. Giraud, J.M. Tréluyer, and G. Chéron Comparison of a morphine and midazolam combination with morphine alone for paediatric displaced fractures: a randomized study Acta Paediatr 100 2011 e203 e207
23. D.K. Cheuk, W.H. Wong, and E. Ma et al. Use of midazolam and ketamine as sedation for children undergoing minor operative procedures Support Care Cancer 13 2005 1001 1009
24. C.M. Hohl, M. Sadatsafavi, B. Nosyk, and A.H. Anis Safety and clinical effectiveness of midazolam versus propofol for procedural sedation in the emergency department: a systematic review Acad Emerg Med 15 2008 1 8