Fat-free mass depletion is associated with poor exercise capacity irrespective of dynamic hyperinflation in COPD patients

Respiratory Care

Volumn 59, Issue 5, 2014, Pages 718-725

  Teopompi, Elisabetta ^a   Tzani, Panagiota ^a   Aiello, Marina ^a   Ramponi, Sara ^a   Andrani, Francesco ^a   Marangio, Emilio ^a   Clini, Enrico ^b   Chetta, Alfredo ^a  

^a UNIVERSITY OF PARMA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Cardiac function; COPD; Dynamic hyperinflation; Exercise; Fat free mass

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; CARBON DIOXIDE; CARBON MONOXIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; METHANE; STEROID; TIOTROPIUM BROMIDE;

ADULT; AGED; ANAEROBIC THRESHOLD; ARTERIAL OXYGEN SATURATION; ARTICLE; BICYCLE ERGOMETRY; BODY COMPOSITION; BODY PLETHYSMOGRAPHY; CARDIOPULMONARY EXERCISE TEST; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DYSPNEA; EXERCISE; EXERCISE ELECTROCARDIOGRAPHY; EXERCISE TOLERANCE; FAT FREE MASS; FEMALE; FORCED EXPIRATORY FLOW; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; HYPERINFLATION; HYPERTENSION; INSPIRATORY CAPACITY; LUNG DIFFUSION CAPACITY; MAJOR CLINICAL STUDY; MALE; MUSCLE FATIGUE; PEAK INSPIRATORY FLOW; PULSE OXIMETRY; SPIROMETRY; ST SEGMENT DEPRESSION; TOTAL LUNG CAPACITY; VISUAL ANALOG SCALE; CARDIOVASCULAR SYSTEM; EXERCISE TEST; HEART RATE; IMPEDANCE; LEG; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGED; ANAEROBIC THRESHOLD; BODY COMPOSITION; CARDIOVASCULAR SYSTEM; CROSS-SECTIONAL STUDIES; DYSPNEA; ELECTRIC IMPEDANCE; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEART RATE; HUMANS; INSPIRATORY CAPACITY; LEG; MALE; MIDDLE AGED; MUSCLE FATIGUE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84893761841     PISSN: 00201324     EISSN: 19433654     Source Type: Journal    
DOI: 10.4187/respcare.02709     Document Type: Article

References (40)

1. Pitta F, Troosters T, Spruit MA, Probst VS, Decramer M, Gosselink R. Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2005;171(9): 972-977.
2. O'Donnell DE. Dynamic hyperinflation and its clinical implication in COPD. Rev Mal Respir 2008;25(10):1305-1318.
3. Garcia-Rio F, Lores V, Mediano O, Rojo B, Hernanz A, López-Collazo E, et al. Daily physical activity in patients with chronic obstructive pulmonary disease is mainly associated with dynamic hyperinflation. Am J Respir Crit Care Med 2009;180(6):506-512.
4. O'Donnell DE. Hyperinflation, dyspnea, and exercise intolerance in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006; 3(2):180-184.
5. Vassaux C, Torre-Bouscoulet L, Zeineldine S, Cortopassi F, Paz-Diaz H, Celli BR, et al. Effects of hyperinflation on the oxygen pulse as a marker of cardiac performance in COPD. Eur Respir J 2008; 32(5):1275-1282.
6. Tzani P, Aiello M, Elia D, Boracchia L, Marangio E, Olivieri D, et al. Dynamic hyperinflation is associated with a poor cardiovascular response to exercise in COPD patients. Respir Res 2011;12:150.
7. Kim HC, Mofarrahi M, Hussain SNA. Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2008;3(4):637-658.
8. Wilson DO, Rogers RM, Wright EC, Anthonisen NR. Body weight in chronic obstructive disease. Am Rev Respir Dis 1989;139(6): 1435-1438.
9. Gray-Donald K, Gibbons L, Shapiro SH, Macklem PT, Martin JG. Nutritional status and mortality in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1996;153(3):961-966.
10. Palange P, Forte S, Felli A, Galassetti P, Serra P, Carlone S. Nutritional state and exercise tolerance in patients with COPD. Chest 1995;107(5):1206-1212.
11. Schols AM, Mostert R, Soeters PB, Wouters EF. Body composition and exercise performance in patients with chronic obstructive pulmonary disease. Thorax 1991;46(10):695-699.
12. Baarends EM, Schols AMWJ, Mostert R, Wouters EFM. Peak exercise response in relation to tissue depletion in patients with chronic obstructive pulmonary disease. Eur Respir J 1997;10(12):2807-2813.
13. Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS, GOLD Scientific Committee. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. Am J Respir Crit Care Med 2001;163(5):1256-1276.
14. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, et al. ATS/ERS Task Force Standardisation of spirometry. Eur Respir J 2005;26(2):319-338.
15. Wanger J, Clausen JL, Coates A, Pedersen OF, Brusasco V, Burgos F, et al. Standardisation of the measurement of lung volumes. Eur Respir J 2005;26(3):511-522.
16. Quanjer PH, Tammeling GJ, Cotes JE, Pedersen OF, Peslin R, Yernault JC. Lung volumes and forced ventilatory flows. Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:5-40.
17. Cotes JE, Chinn DJ, Quanjer PH, Roca J, Yernault JC. Standardization of the measurement of transfer factor (diffusing capacity). Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal Official Statement of the European Respiratory Society. Eur Respir J Suppl 1993;16:41-52.
18. American Thoracic Society, American College of Chest Physicians. Statement on cardiopulmonary exercise testing. Am J Respir Crit Care Med 2003;167(2):211-277.
19. Stubbing DG, Pengelly LD, Morse JL, Jones NL. Pulmonary mechanics during exercise in subjects with chronic airflow obstruction. J Appl Physiol 1980;49(3):511-515.
20. Zafar MA, Tsuang W, Lach L, Eschenbacher W, Panos RJ. Dynamic hyperinflation correlates with exertional oxygen desaturation in patients with chronic obstructive pulmonary disease. Lung 2013;191(2): 177-182.
21. Baba R, Nagashima M, Goto M, Nagano Y, Yokota M, Tauchi N, et al. Oxygen uptake efficiency slope: a new index of cardiorespiratory functional reserve derived from the relation between oxygen uptake and minute ventilation during incremental exercise. J Am Coll Cardiol 1996;28(6):1567-1572.
22. Cole CR, Blackstone EH, Pashkow FJ, Snader CE, Lauer MS. Heart-rate recovery immediately after exercise as a predictor of mortality. N Engl J Med 1999;341(18):1351-1357.
23. Brooks SM. Surveillance for respiratory hazards. ATS News 1982; 8:12-16.
24. Tzani P, Piepoli MF, Longo F, Aiello M, Serra W, Maurizio AR, et al. Resting lung function in the assessment of the exercise capacity in patients with chronic heart failure. Am J Med Sci 2010;339(3): 210-215.
25. Segal KR, Van Loan M, Fitzgerald PI, Hogdon JA, Van Itallie TB. Lean body mass estimation by bioelectrical impedance analysis: a four-site cross-validation study. Am J Clin Nutr 1988;47(1):7-14.
26. Kyle UG, Y Schutz, Dupertuis YM, Pichard C. Body composition interpretation: contributions of the fat-free mass index and the body fat mass index. Nutrition 2003;19(7/8):597-604.
27. Wasserman K, Hansen JE, Sue DY, Stringer WW, Sietsema KE, Sun X-G, et al. Normal values. In: Principles of exercise testing and interpretation. Philadelphia: Lippincott Williams & Wilkins;1994: 143-162.
28. Schols AMW, Soeters PB, Dingemans AMC, Mostert R, Frantzen PJ, Wouters EFM. Prevalence and characteristics of nutritional depletion in patients with stable COPD eligible for pulmonary rehabilitation. Am Rev Respir Dis 1993;147(5):1151-1156.
29. Vermeeren MA, Creutzberg EC, Schols AM, Postma DS, Pieters WR, Roldaan AC, et al. Prevalence of nutritional depletion in a large out-patient population of patients with COPD. Respir Med 2006; 100(8):1349-1355.
30. Crisafulli E, Costi S, Clini EM. Anthropometry as measure of risk in COPD patients. In: Preedy VR, editor. Handbook on anthropometry: physical measures of human form in health and disease. Berlin: Springer Science Business Media LLC;2012:2357-2371.
31. Collins PF, Stratton RJ, Elia M. Nutritional support in chronic obstructive pulmonary disease: a systematic review and meta-analysis. Am J Clin Nutr 2012;95(6):1385-1395.
32. Baarends EM, Schols AM, Pannemans DL, Westerterp KR, Wouters EF. Total free living energy expenditure in patients with severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1997;155(2):549-554.
33. Nishimura Y, Tsutsumi M, Nakata H, Tsunenari T, Maeda H, Yokoyama M. Relationship between respiratory muscle strength and lean body mass in men with COPD. Chest 1995;107(5):1232-1236.
34. Piitulainen E, Areberg J, Lindén M, Eriksson S, Mattsson S, Wollmer P. Nutritional status and muscle strength in patients with emphysema and severe alpha(1)-antitrypsin deficiency. Chest 2002;122(4):1240-1246.
35. Whipp BJ, Higgenbotham MB, Cobb FC. Estimating exercise stroke volume from asymptotic oxygen pulse in humans. J Appl Physiol 1996;81(6):2674-2679.
36. Hollenberg M, Tager IB. Oxygen uptake efficiency slope: an index of exercise performance and cardiopulmonary reserve requiring only submaximal exercise. J Am Coll Cardiol 2000;36(1):194-201.
37. Akkerman M, van Brussel M, Hulzebos E, Vanhees L, Helders PJ, Takken T. The oxygen uptake efficiency slope: what do we know? J Cardiopulm Rehabil Prev 2010;30(6):357-373.
38. Lacasse M, Maltais M, Poirier P, Lacasse Y, Marquis K, Jobin J, et al. Post-exercise heart rate recovery and mortality in chronic obstructive pulmonary disease. Respir Med 2005;99(7):877-886.
39. Sheriff D. Point: the muscle pump raises muscle blood flow during locomotion. J Appl Physiol 2005;99(1):371-372.
40. Sheriff DD. Local and reflex regulation of muscle blood flow during dynamic exercise. In: Exercise, nutrition, and environmental stress. Vol. 2. Traverse City, MI: IL Cooper;2002:19-44.