Dynamic hyperinflation correlates with exertional oxygen desaturation in patients with chronic obstructive pulmonary disease

Lung

Volumn 191, Issue 2, 2013, Pages 177-182

  Zafar, Muhammad Ahsan ^a   Tsuang, Wayne ^a   Lach, Laura ^a   Eschenbacher, William ^a   Panos, Ralph J ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

COPD; Desaturation; Dynamic hyperinflation; Exertion

Indexed keywords

OXYGEN;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BODY MASS; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; DYNAMIC HYPERINFLATION; EXERTIONAL OXYGEN DESATURATION; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; HYPERINFLATION; INSPIRATORY CAPACITY; LUNG FUNCTION; MALE; OXYGEN DESATURATION; OXYGEN SATURATION; PREDICTION; PRIORITY JOURNAL; PULSE OXIMETRY; RECEIVER OPERATING CHARACTERISTIC; REGRESSION ANALYSIS; SENSITIVITY AND SPECIFICITY; SMOKING; SPIROMETER; UNIVARIATE ANALYSIS; WALKING;

AGED; CHI-SQUARE DISTRIBUTION; DYSPNEA; EXERCISE TEST; EXERCISE TOLERANCE; FORCED EXPIRATORY VOLUME; HUMANS; INHALATION; LUNG; MALE; MAXIMAL MIDEXPIRATORY FLOW RATE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OXIMETRY; OXYGEN; PHYSICAL EXERTION; PREDICTIVE VALUE OF TESTS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; ROC CURVE; SPIROMETRY; VITAL CAPACITY;

EID: 84880572056     PISSN: 03412040     EISSN: 14321750     Source Type: Journal    
DOI: 10.1007/s00408-012-9443-3     Document Type: Article

References (29)

1. Casanova C, Cote C, Marin JM et al (2008) Distance and oxygen desaturation during 6-min walk test as predictors of long-term mortality in patients with COPD. Chest 134:746-752
2. Panos RJ, Eschenbacher W (2009) Exertional desaturation in patients with chronic obstructive pulmonary disease. COPD 6:478-487
3. Emmanuel GE, Monreno F (1966) Distribution of ventilation and blood flow during exercise in emphysema. J Appl Physiol 21:1532-1544
4. Cutillo A, Bigler AH, Perondi R et al (1981) Exercise and distribution of inspired gas in patients with obstructive pulmonary disease. Bull Eur Physiopathol Respir 17:891-901
5. Dantzker DR, D'Alonzo GE (1986) The effect of exercise on pulmonary gas exchange in patients with severe chronic obstructive pulmonary disease. Am Rev Respir Dis 134:1135-1139
6. Owens GR, Rogers RM, Pennock BE et al (1984) The diffusing capacity as a predictor of arterial oxygen desaturation during exercise in patients with chronic obstructive pulmonary disease. N Engl J Med 310(19):1218-1221
7. Knower MT, Dunagan DP, Adair NE et al (2001) Baseline oxygen saturation predicts exercise desaturation below prescription threshold in patients with chronic obstructive pulmonary disease. Arch Intern Med 161(5):732-736
8. Blanch L, Bernabé F, Lucangelo U (2005) Measurement of air trapping, intrinsic positive end-expiratory pressure and dynamic hyperinflation in mechanically ventilated patients. Respir Care 50:110-123
9. Parker CM, Voduc N, Aaron SD et al (2005) Physiological changes during symptom recovery from moderate exacerbations of COPD. Eur Respir J 26:420-428
10. Satevenson NJ, Walker PP, Costello RW et al (2005) Lung mechanics and dyspnea during exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med 172:1510-1516
11. Gelb AF, Guitierrez CA, Weisman IM et al (2004) Simplified detection of dynamic hyperinflation. Chest 126:1855-1860
12. O'Donnell DE, Revill S, Webb KA (2001) Dynamic hyperinflation and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 164:770-777
13. Hannink JD, Van Helvoort HA, Dekhuijzen PN et al (2011) Similar dynamic hyperinflation during arm and leg exercise at similar ventilation in chronic obstructive pulmonary disease. Med Sci Sports Exerc 43(6):996-1001
14. Callens E, Graba S, Gillet-Juvin K et al (2009) Measurement of dynamic hyperinflation after a 6-minute walk test in patients with COPD. Chest 136(6):1466-1472
15. Barbera JA, Roca J, Ramirez J et al (1991) Gas exchange during exercise in mild COPD. Correlation with lung structure. Am Rev Respir Dis 144:520-525
16. Tzani P, Aiello M, Elia D et al (2011) Dynamic hyperinflation is associated with a poor cardiovascular response to exercise in COPD patients. Respir Res 12:150
17. Vassaux C, Torre-Bouscoulet L, Zeineldine S et al (2008) Effects of hyperinflation on the oxygen pulse as a marker of cardiac performance in COPD. Eur Respir J 32(5):1275-1282
18. O'Donnell DE, D'Arsigny C, Fitzpatrick M et al (2002) Exercise hypercapnia in advanced chronic obstructive pulmonary disease: the role of lung hyperinflation. Am J Respir Crit Care Med 166:663-668
19. ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories (2002) ATS statement: guidelines for the six-minute walk test. Am J Respir Crit Care Med 166:111-117
20. Wilson RC, Jones PW (1989) A comparison of the visual analogue scale and modified Borg scale for the measurement of dyspnoea during exercise. Clin Sci (Lond) 76(3):277-282
21. Miller MR, Hankinson J, Brusasco V et al (2005) Standardisation of spirometry. Eur Respir J 26:319-338
22. Global Initiative for Chronic Obstructive Lung Disease: global strategy for the diagnosis, management and prevention of chronic obstructive lung disease. http://www.goldcopd.com. Accessed 10 Aug 2012
23. Jenkins S, Čečins N (2011) Six-minute walk test: observed adverse events and oxygen desaturation in a large cohort of patients with chronic lung disease. Intern Med J 41(5):416-422
24. Lahaije AJ, van Helvoort HA, Dekhuijzen PN et al (2010) Physiologic limitations during daily life activities in COPD patients. Respir Med 104(8):1152-1159
25. Garcia-Rio F, Lores V, Mediano O et al (2009) Daily physical activity in patients with chronic obstructive pulmonary disease is mainly associated with dynamic hyperinflation. Am J Respir Crit Care Med 180(6):506-512
26. Guenette JA, Webb KA, O'Donnell DE (2012) Does dynamic hyperinflation contribute to dyspnoea during exercise in patients with COPD? Eur Respir J 40(2):322-329
27. Hannink JD, van Helvoort HA, Dekhuijzen PN et al (2010) Dynamic hyperinflation during daily activities: does COPD global initiative for chronic obstructive lung disease stage matter? Chest 137(5):1116-1121
28. Hannink J, Lahaije A, Bischoff E et al (2010) Dynamic hyperinflation after metronome-paced hyperventilation in COPD: a 2 year follow-up. Respir Med 104(11):1700-1705
29. Guenette JA, Jensen D, Webb KA et al (2011) Sex differences in exertional dyspnea in patients with mild COPD: physiological mechanisms. Respir Physiol Neurobiol 177(3):218-227