Emergence of extended-spectrum β-lactamase producing Enterobacter spp. in patients with bacteremia in a tertiary hospital in southern Brazil

Enfermedades Infecciosas y Microbiologia Clinica

Volumn 32, Issue 2, 2014, Pages 87-92

  Da Silva Nogueira, Keite ^a   Paganini, Maria Cristina ^a   Conte, Andréia ^a   Cogo, Laura Lúcia ^a   Taborda De Messias Reason, Iara ^a   Da Silva, Márcio José ^b   Dalla Costa, Libera Maria ^a,c  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c INSTITUTO DE PESQUISA PELÉ PEQUENO PRÍNCIPE   (Brazil)

Author keywords

Bacteremia; Enterobacter; ESBL; Extended spectrum lactamase

Indexed keywords

CARBAPENEM; CEFTAZIDIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; ANTIINFECTIVE AGENT; AZTREONAM; BETA LACTAMASE; BETA LACTAMASE CTX M; BETA LACTAMASE CTX M 15; BETA LACTAMASE CTX M 2; BETA LACTAMASE CTX M 59; BETA LACTAMASE PER 2; BETA LACTAMASE SHV; BETA LACTAMASE SHV 12; CARBAPENEM DERIVATIVE; CEFOTAXIME; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG; BACTERIAL PROTEIN;

ADOLESCENT; ADULT; AGED; ANTIMICROBIAL THERAPY; ARTICLE; BACTEREMIA; BACTERIAL GENE; BLOOD CULTURE; BRAZIL; CHILD; COMPARATIVE STUDY; ENTEROBACTER AEROGENES; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE INFECTION; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING ENTEROBACTERIACEAE; GENETIC SIMILARITY; HOSPITALIZATION; HUMAN; INFANT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MIDDLE AGED; MORTALITY; NEWBORN; NUCLEOTIDE SEQUENCE; PNEUMONIA; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PULSED FIELD GEL ELECTROPHORESIS; RETROSPECTIVE STUDY; RISK FACTOR; SCHOOL CHILD; TERTIARY CARE CENTER; VERY ELDERLY; YOUNG ADULT; ABDOMINAL INFECTION; ANTIBIOTIC SENSITIVITY; ARTIFICIAL VENTILATION; BACTERIAL STRAIN; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BLA CTX M GENE; BLA PER GENE; BLA SHV GENE; BLA TEM GENE; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; ENTEROBACTER; ENTEROBACTER GERGOVIAE; GASTROINTESTINAL DISEASE; HEART DISEASE; HOSPITAL DISCHARGE; HOSPITAL INFECTION; HOSPITAL PATIENT; INFECTION; INTENSIVE CARE; KIDNEY DISEASE; MOLECULAR CLONING; NEOPLASM; NEUROLOGIC DISEASE; NONHUMAN; NOSOCOMIAL PNEUMONIA; PREVALENCE; RESPIRATORY TRACT DISEASE; SURGERY; SURGICAL WOUND; TRACHEOSTOMY; URINARY CATHETER; URINARY TRACT INFECTION; ANTIBIOTIC RESISTANCE; ENTEROBACTERIACEAE INFECTIONS; ENZYME SPECIFICITY; ENZYMOLOGY; FEMALE; GENETICS; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; STATISTICS AND NUMERICAL DATA; TEACHING HOSPITAL; TREATMENT OUTCOME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; BRAZIL; CHILD; CHILD, PRESCHOOL; ENTEROBACTER; ENTEROBACTERIACEAE INFECTIONS; FEMALE; GENES, BACTERIAL; HOSPITAL MORTALITY; HOSPITALS, TEACHING; HUMANS; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; PREVALENCE; RETROSPECTIVE STUDIES; RISK FACTORS; SUBSTRATE SPECIFICITY; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84893744149     PISSN: 0213005X     EISSN: 15781852     Source Type: Journal    
DOI: 10.1016/j.eimc.2013.02.004     Document Type: Article

References (19)

1. W.E. Sanders Jr., and C.C. Sanders Enterobacter spp.: pathogens poised to flourish at the turn of the century Clin Microbiol Rev 10 1997 220 241
2. P.L. Ho, R.H. Shek, K.H. Chow, and W.M. Lai Detection and characterization of extended-spectrum beta-lactamases among bloodstream isolates of Enterobacter spp. in Hong Kong, 2000-2002 J Antimicrob Chemother 55 2005 326 332
3. K.S. Thomson Extended-spectrum-β-lactamase, AmpC, and carbapenemase issues J Clin Microbiol 48 2010 1019 1025
4. J. Rodríguez-Baño, E. Picón, P. Gijón, J.R. Hernández, J.M. Cisneros, and C. Peña et al. Risk factors and prognosis of nosocomial bloodstream infections caused by extended-spectrum-beta- lactamase-producing Escherichia coli J Clin Microbiol 48 2010 1726 1731
5. M.J. Schwaber, and Y. Carmeli Mortality and delay in effective therapy associated with extended-spectrum beta-lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta-analysis J Antimicrob Chemother 60 2007 913 920
6. M. Tumbarello, T. Spanu, R. Di Bidino, M. Marchetti, M. Ruggeri, and E.M. Trecarichi et al. Costs of bloodstream infections caused by Escherichia coli and influence of extended-spectrum-beta-lactamase production and inadequate initial antibiotic therapy Antimicrob Agents Chemother 54 2010 4085 4091
7. H.S. Cheong, K.S. Ko, C.I. Kang, D.R. Chung, K.R. Peck, and J.H. Song Clinical significance of infections caused by extended-spectrum b-lactamase-producing Enterobacteriaceae Blood isolates with inducible AmpC b-lactamase Microbial Drug Resist 18 2012 446 452
8. T.G. Towne, J.S. Lewis, M. Herrera, B. Wickes, and J.H. Jorgensen Detection of SHVtype extended-spectrum beta-lactamase in Enterobacter isolates J Clin Microbiol 48 2010 298 299
9. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial. Susceptibility Testing; Twenty-First Informational Supplement M100-S21. CLSI, Wayne, PA, USA, 2011.
10. N. Woodford, E.J. Fagan, and M.J. Ellington Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum (beta)-lactamases J Antimicrob Chemother 57 2006 154 155
11. J.P. Payne, and D.J. Thomson Molecular approaches for the detection and identification of β-lactamases N. Woodford, A.P. Johnson, Molecular bacteriology: protocols and clinical applications 1998 Humana Press Totowa, NJ, USA 495 512
12. A. Bauernfeind, I. Stemplinger, R. Jungwirth, P. Mangold, S. Amann, and E. Akalin et al. Characterization of beta-lactamase gene blaPER-2, which encodes an extended-spectrum class A beta-lactamase Antimicrob Agents Chemother 40 1996 616 620
13. M. Kaufmann Pulsed-field-gel-electrophoresis N. Woodford, A.P. Johnson, Molecular bacteriology: protocols and clinical applications 1988 Human Press NJ 33 51
14. N. Gupta, Aparna, U. Choudhary, N. Garg, and D.R. Arora Enterobacter bacteremia J. Assoc Physicians India 51 2003 669 672
15. D. Marchaim, T. Gottesman, O. Schwartz, M. Korem, Y. Maor, and G. Rahav et al. National multicenter study of predictors and outcomes of bacteremia upon hospital admission caused by Enterobacteriaceae producing extended-spectrum beta-lactamases Antimicrob Agents Chemother 54 2010 5099 5104
16. H. Pai, J.Y. Hong, J.H. Byeon, Y.K. Kim, and H.J. Lee High prevalence of extended-spectrum beta-lactamase-producing strains among blood isolates of Enterobacter spp. collected in a tertiary hospital during an 8-year period and their antimicrobial susceptibility patterns Antimicrob Agents Chemother 48 2004 3159 3161
17. A. García-Hernández, E. García-Vázquez, J. Gómez-Gómez, M. Canteras, A. Hernandez-Torres, and J. Ruiz-Gomes Predictor factors of ESBL versus non-ESBL Escherichia coli bacteraemia and influence of resistance on the mortality of the patients Med Clin (Barc) 136 2010 56 60
18. M. Marcos, A. Iñurrieta, A. Soriano, J.A. Martínez, M. Almela, and F. Marco et al. Effect of antimicrobial therapy on mortality in 377 episodes of Enterobacter spp. bacteraemia J Antimicrob Chemother 62 2008 397 403
19. R. Bonnet, C. Dutour, J.L.M. Sampaio, C. Chanal, D. Sirot, and R. Labia et al. Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240→Gly Antimicrob Agents Chemother 45 2001 2269 2275