Clinical significance of infections caused by extended-spectrum β-lactamase-producing Enterobacteriaceae blood isolates with inducible AmpC β-lactamase

Microbial Drug Resistance

Volumn 18, Issue 4, 2012, Pages 446-452

  Cheong, Hae Suk ^a   Ko, Kwan Soo ^b   Kang, Cheol In ^b   Chung, Doo Ryeon ^b   Peck, Kyong Ran ^b   Song, Jae Hoon ^b  

^a Konkuk University Hospital   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE AMPC; CEFEPIME; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BACTERIUM ISOLATE; BLOODSTREAM INFECTION; CHILD; CITROBACTER; CITROBACTER BRAKII; CITROBACTER FREUNDII; CLINICAL FEATURE; CONTROLLED STUDY; DRUG UTILIZATION; ENTEROBACTER; ENTEROBACTER AEROGENES; ENTEROBACTER CANCEROGENUS; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE INFECTION; ENZYME INDUCTION; ENZYME SYNTHESIS; EXTENDED SPECTRUM BETA LACTAMASE PRODUCING ENTEROBACTERIACEAE; FEMALE; HEALTH CARE COST; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INDWELLING CATHETER; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORGANELLA MORGANII; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; SERRATIA; SERRATIA FONTICOLA; SERRATIA MARCESCENS;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTEREMIA; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CARBAPENEMS; CEPHALOSPORINS; CHILD; CHILD, PRESCHOOL; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; ENZYME INDUCTION; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFANT; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; RISK FACTORS; SURVIVAL RATE; YOUNG ADULT;

CITROBACTER; ENTEROBACTER; ENTEROBACTERIACEAE; MORGANELLA MORGANII; SERRATIA;

EID: 84864334356     PISSN: 10766294     EISSN: 19318448     Source Type: Journal    
DOI: 10.1089/mdr.2011.0126     Document Type: Article

References (22)

1. Ariffin, H., P. Navaratnam, M. Mohamed, A. Arasu, W.A. Abdullah, C.L. Lee, and L.H. Peng. 2000. Ceftazidimeresistant Klebsiella pneumoniae bloodstream infection in children with febrile neutropenia. Int. J. Infect. Dis. 4:21-25.
2. Bell, J.M., J.D. Turnidge, and R.N. Jones. 2003. Prevalence of extended-spectrum beta-lactamase-producing Enterobacter cloacae in the Asia-Pacific region: Results from the SENTRY Antimicrobial Surveillance Program, 1998 to 2001. Antimicrob. Agents Chemother. 47:3989-3993.
3. Cheong, H., K. Ko, C. Kang, D. Chung, K. Peck, and S. Song. 2010. Prevalence of extended-spectrum betalactamase among Enterobacteriacae blood isolates with inducible AmpC beta-lactamase. Infect. Chemother. 42:280-284.
4. Choi, S.H., J.E. Lee, S.J. Park, M.N. Kim, E.J. Choo, Y.G. Kwak, J.Y. Jeong, J.H. Woo, N.J. Kim, and Y.S. Kim. 2007. Prevalence, microbiology, and clinical characteristics of extended-spectrum beta-lactamase-producing Enterobacter spp., Serratia marcescens, Citrobacter freundii, and Morganella morganii in Korea. Eur. J. Clin. Microbiol. Infect. Dis. 26: 557-561.
5. Chow, J.W., and V.L. Yu. 1999. Combination antibiotic therapy versus monotherapy for gram-negative bacteraemia: A commentary. Int. J. Antimicrob. Agents 11:7-12.
6. Du, B., Y. Long, H. Liu, D. Chen, D. Liu, Y. Xu, and X. Xie. 2002. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae bloodstream infection: Risk factors and clinical outcome. Intensive Care Med. 28:1718-1723.
7. Emery, C.L., and L.A. Weymouth. 1997. Detection and clinical significance of extended-spectrum beta-lactamases in a tertiary-care medical center. J. Clin. Microbiol. 35:2061-2067.
8. Fauci, A.S., E. Braunwald, D.L. Kasper, S.L. Hauser, D.L. Longo, J.L. Jameson, and R.N. Jones. 2008. Harrison's Principles of Internal Medicine, 17th ed., McGraw-Hill, New York.
9. Ho, P.L., W.M. Chan, K.W. Tsang, S.S. Wong, and K. Young. 2002. Bacteremia caused by Escherichia coli producing extended-spectrum beta-lactamase: A case-control study of risk factors and outcomes. Scand. J. Infect. Dis. 34:567-573.
10. Kim, B.N., J.H. Woo, M.N. Kim, J. Ryu, and Y.S. Kim. 2002. Clinical implications of extended-spectrum beta-lactamaseproducing Klebsiella pneumoniae bacteraemia. J. Hosp. Infect. 52:99-106.
11. Kim, J., and Y.M. Lim. 2005. Prevalence of derepressed ampC mutants and extended-spectrum beta-lactamase producers among clinical isolates of Citrobacter freundii, Enterobacter spp., and Serratia marcescens in Korea: Dissemination of CTX-M-3, TEM-52, and SHV-12. J. Clin. Microbiol. 43:2452-2455.
12. Kim, Y.K., H. Pai, H.J. Lee, S.E. Park, E.H. Choi, J. Kim, J.H. Kim, and E.C. Kim. 2002. Bloodstream infections by extended-spectrum beta-lactamase- producing Escherichia coli and Klebsiella pneumoniae in children: Epidemiology and clinical outcome. Antimicrob. Agents Chemother. 46:1481-1491.
13. Lautenbach, E., J.B. Patel, W.B. Bilker, P.H. Edelstein, and N.O. Fishman. 2001. Extended-spectrum beta-lactamaseproducing Escherichia coli and Klebsiella pneumoniae: Risk factors for infection and impact of resistance on outcomes. Clin. Infect. Dis. 32:1162-1171.
14. Lesens, O., C. Methlin, Y. Hansmann, V. Remy, M. Martinot, C. Bergin, P. Meyer, and D. Christmann. 2003. Role of comorbidity in mortality related to Staphylococcus aureus bacteremia: A prospective study using the Charlson weighted index of comorbidity. Infect. Control Hosp. Epidemiol. 24:890-896.
15. Livermore, D.M., and D.F. Brown. 2001. Detection of betalactamase- mediated resistance. J. Antimicrob. Chemother. 48 Suppl 1:59-64.
16. Pai, H., J.Y. Hong, J.H. Byeon, Y.K. Kim, and H.J. Lee. 2004. High prevalence of extended-spectrum beta-lactamaseproducing strains among blood isolates of Enterobacter spp. collected in a tertiary hospital during an 8-year period and their antimicrobial susceptibility patterns. Antimicrob. Agents Chemother. 48:3159-3161.
17. Park, Y.J., S.Y. Park, E.J. Oh, J.J. Park, K.Y. Lee, G.J. Woo, and K. Lee. 2005. Occurrence of extended-spectrum betalactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteria. Diagn. Microbiol. Infect. Dis. 51:265-269.
18. Paterson, D.L. 2006. Resistance in gram-negative bacteria: Enterobacteriaceae. Am. J. Med. 119:S20-S28; discussion S62-S70.
19. Pitout, J.D., M.D. Reisbig, E.C. Venter, D.L. Church, and N.D. Hanson. 2003. Modification of the double-disk test for detection of enterobacteriaceae producing extendedspectrum and AmpC beta-lactamases. J. Clin. Microbiol. 41: 3933-3935.
20. Ramphal, R., and P.G. Ambrose. 2006. Extended-spectrum beta-lactamases and clinical outcomes: Current data. Clin. Infect. Dis. 42 Suppl 4:S164-S172.
21. Schiappa, D.A., M.K. Hayden, M.G. Matushek, F.N. Hashemi, J. Sullivan, K.Y. Smith, D. Miyashiro, J.P. Quinn, R.A. Weinstein, and G.M. Trenholme. 1996. Ceftazidimeresistant Klebsiella pneumoniae and Escherichia coli bloodstream infection: A case-control and molecular epidemiologic investigation. J. Infect. Dis. 174:529-536.
22. Yang, J.L., J.T. Wang, T.L. Lauderdale, and S.C. Chang. 2009. Prevalence of extended-spectrum beta-lactamases in Enterobacter cloacae in Taiwan and comparison of 3 phenotypic confirmatory methods for detecting extended-spectrum beta-lactamase production. J. Microbiol. Immunol. Infect. 42:310-316.