Human neural stem cells expressing carboxyl esterase target and inhibit tumor growth of lung cancer brain metastases

Cancer Gene Therapy

Volumn 20, Issue 12, 2013, Pages 678-682

  Hong, S H ^a   Lee, H J ^b   An, J ^b   Lim, I ^b   Borlongan, C ^c   Aboody, K S ^d   Kim, S U ^b,e  

^a University of Ulsan College of Medicine   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

carboxyl esterase; CPT 11; human neural stem cell; lung cancer; metastatic brain tumor; suicide gene

Indexed keywords

BEVACIZUMAB; CARBOXYLESTERASE; CYTOSINE DEAMINASE; FIRTECAN; IRINOTECAN; PRODRUG; RETROVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN METASTASIS; BRAIN TUMOR; BYSTANDER EFFECT; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER GENE THERAPY; CANCER INHIBITION; CELL SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; GENETIC ENGINEERING; GENETIC TRANSDUCTION; GLIOBLASTOMA; GLIOMA; GROWTH INHIBITION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG NON SMALL CELL CANCER; METASTASIS INHIBITION; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; SUICIDE GENE; TUMOR GROWTH; TUMOR VOLUME;

ANIMALIA; MUS; ORYCTOLAGUS CUNICULUS;

ANIMALS; BRAIN NEOPLASMS; BYSTANDER EFFECT; CARBOXYLESTERASE; CELL LINE; CELL LINE, TUMOR; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HUMANS; LUNG NEOPLASMS; NEURAL STEM CELLS; RABBITS; TUMOR BURDEN;

EID: 84893738612     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2013.69     Document Type: Article

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