Efficacy and safety of iguratimod for the treatment of rheumatoid arthritis

Clinical and Developmental Immunology

Volumn 2013, Issue , 2013, Pages

  Li, Jiangtao ^a,b   Mao, Hejuan ^b   Liang, Yan ^a   Lu, Yanrong ^a   Chen, Shuo ^a   Yang, Nanping ^a   Shi, Guixiu ^c  

^a SICHUAN UNIVERSITY   (China)

^b First People's Hospital of Yibin   (China)

^c THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMONE DERIVATIVE; IGURATIMOD; IMMUNOSUPPRESSIVE AGENT; SULFONAMIDE;

HUMAN; META ANALYSIS; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; RHEUMATOID ARTHRITIS; RISK; TREATMENT OUTCOME;

ARTHRITIS, RHEUMATOID; CHROMONES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; ODDS RATIO; RANDOMIZED CONTROLLED TRIALS AS TOPIC; SULFONAMIDES; TREATMENT OUTCOME;

EID: 84893735702     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2013/310628     Document Type: Review

References (19)

1. O'Dell J. R., Goldman L., Schafer A. I., Rheumatoid arthritis. Goldman's Cecil Medicine 2012 24th chapter 272 Elsevier/Saunders 1681 1689
2. Lü L. J., Teng J. L., Bao C. D., Han X. H., Sun L. Y., Xu J. H., Li X. F., Wu H. X., Safety and efficacy of T-614 in the treatment of patients with active rheumatoid arthritis: a double blind, randomized, placebo-controlled and multicenter trial. Chinese Medical Journal 2008 121 7 615 619 2-s2.0-46449101583
3. World Health Organization, Good health adds life to years global brief for World Health Day 2012. WHO Document Production Services 2012 Geneva, Switzerland WHO
4. Du F., Lü L. J., Fu Q., Dai M., Teng J. L., Fan W., Chen S. L., Ye P., Shen N., Huang X. F., Qian J., Bao C. D., T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis. Arthritis Research and Therapy 2008 10 6, article R136 2-s2.0-57649112539 10.1186/ar2554
5. Kohno M., Aikawa Y., Tsubouchi Y., Hashiramoto A., Yamada R., Kawahito Y., Inoue K. I., Kusaka Y., Kondo M., Sano H., Inhibitory effect of T-614 on tumor necrosis factor- α induced cytokine production and nuclear factor- B activation in cultured human synovial cells. Journal of Rheumatology 2001 28 12 2591 2596 2-s2.0-0035204246 (Pubitemid 33135640)
6. Tanaka K., Yamamoto T., Aikawa Y., Kizawa K., Muramoto K., Matsuno H., Muraguchi A., Inhibitory effects of anti-rheumatic agent T-614 on immunoglobulin production by cultured B cells and rheumatoid synovial tissues engrafted into SCID mice. Rheumatology 2003 42 11 1365 1371 2-s2.0-0242609352 10.1093/rheumatology/keg381 (Pubitemid 37407028)
7. Du F., Lü L. J., Teng J. L., Shen N., Ye P., Bao C. D., T-614 alters the production of matrix metalloproteinases (MMP-1 andMMP-3) and inhibits the migratory expansion of rheumatoid synovial fibroblasts, in vitro. International Immunopharmacology 2012 13 1 54 60 2-s2.0-84859153165 10.1016/j.intimp.2012.03. 003
8. OMERACT conference on outcome measures in rheumatoid arthritis clinical trials. Journal of Rheumatology 1993 20 3 526 591
9. Felson D. T., Anderson J. J., Boers M., Bombardier C., Furst D., Goldsmith C., Katz L. M., Lightfoot R. Jr., Paulus H., Strand V., Tugwell P., Weinblatt M., Williams H. J., Wolfe F., Kieszak S., American College of Rheumatology preliminary definition of improvement in rheumatoid arthritis. Arthritis and Rheumatism 1995 38 6 727 735 2-s2.0-0029044362 10.1002/art.1780380602
10. van Gestel A. M., Prevoo M. L. L., Van 'T Hof M. A., Van Rijswijk M. H., Van De Putte L. B. A., Van Riel P. L. C. M., Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis. Arthritis and Rheumatism 1996 39 1 34 40 2-s2.0-0030068817 (Pubitemid 126575924)
11. International Conference on Harmonisation Expert Working Group, International conference on harmonisation of technical requirements for registration of pharmaceuticals for human use. ICH harmonised tripartite guideline. Guideline for good clinical practice. 1997 CFR & ICH Guidelines 1997 Philadelphia, Pa, USA Barnett International/PAREXEL
12. Higgins J. P. T., Altman D. G., Sterne J. A. C., Higgins J. P. T., Green S., Assessing risk of bias in included studies. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 2011 Chapter 8 The Cochrane Collaboration. http://handbook.cochrane.org/
13. Schünemann H., Brożek J., Oxman A., GRADE Handbook for Grading Quality of Evidence and Strength of Recommendation 2009 version 3.2 The GRADE Working Group. http://www.cc-ims.net/gradepro
14. Lu L. J., Bao C. D., Dai M., Teng J. L., Fan W., Du F., Yang N. P., Zhao Y. H., Chen Z. W., Xu J. H., He P. G., Wu H. X., Tao Y., Zhang M. J., Han X. H., Li X. F., Gu J. R., Li J. H., Yu H., Multicenter, randomized, double-blind, controlled trial of treatment of active rheumatoid arthritis with T-614 compared with methotrexate. Arthritis Care and Research 2009 61 7 979 987 2-s2.0-67650470192 10.1002/art.24643
15. Hara M., Abe T., Sugawara S., Mizushima Y., Hoshi K., Irimajiri S., Hashimoto H., Yoshino S., Matsui N., Nobunaga M., Nakano S., Efficacy and safety of iguratimod compared with placebo and salazosulfapyridine in active rheumatoid arthritis: a controlled, multicenter, double-blind, parallel-group study. Modern Rheumatology 2007 17 1 1 9 2-s2.0-34247593508 10.1007/s10165-006- 0542-y (Pubitemid 46758763)
16. Ishiguro N., Yamamoto K., Katayama K., Kondo M., Sumida T., Mimori, Mimori T., Soen S., Nagai K., Yamaguchi T., Hara M., Concomitant iguratimod therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate: a randomized, double-blind, placebo-controlled trial. Modern Rheumatology 2013 23 3 430 439 10.1007/s10165-012-0724-8
17. Arnett F. C., Edworthy S. M., Bloch D. A., McShane D. J., Fries J. F., Cooper N. S., Healey L. A., Kaplan S. R., Liang M. H., Luthra H. S., Medsger T. A. Jr., Mitchell D. M., Neustadt D. H., Pinals R. S., Schaller J. G., Sharp J. T., Wilder R. L., Hunder G. G., The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis and Rheumatism 1988 31 3 315 324 2-s2.0-0023945481 (Pubitemid 18091653)
18. Hochberg M. C., Chang R. W., Dwosh I., Lindsey S., Pincus T., Wolfe F., The American College of Rheumatology 1991 revised criteria for the classification of global functional status in rheumatoid arthritis. Arthritis and Rheumatism 1992 35 5 498 502 2-s2.0-0026629688
19. Hara M., Abe T., Sugawara S., Mizushima Y., Hoshi K., Irimajiri S., Hashimoto H., Yoshino S., Matsui N., Nobunaga M., Long-term safety study of iguratimod in patients with rheumatoid arthritis. Modern Rheumatology 2007 17 1 10 16 2-s2.0-34247646059 10.1007/s10165-006-0543-x (Pubitemid 46758764)