Utility of neuropsychiatric tools in the differential diagnosis of dementia with Lewy bodies and Alzheimer's disease: Quantitative and qualitative findings

International Psychogeriatrics

Volumn 26, Issue 3, 2014, Pages 453-461

  Suárez González, Aida ^a   Serrano Pozo, Alberto ^a,d   Arroyo Anlló, Eva M ^b   Franco Macías, Emilio ^a   Polo, Juan ^c   García Solís, David ^a   Gil Néciga, Eulogio ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^b UNIVERSITY OF SALAMANCA   (Spain)

^c UNIVERSITY OF SEVILLE   (Spain)

^d UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Alzheimer's disease; Columbia University Scale for Psychopathology in Alzheimer's Disease (CUSPAD); Delusional misidentifications; Dementia with Lewy bodies; Hallucinations; Illusions; Neuropsychiatric Inventory (NPI)

Indexed keywords

DOPAMINE TRANSPORTER; CHOLINESTERASE INHIBITOR; DOPAMINE RECEPTOR BLOCKING AGENT; LEVODOPA; NEUROLEPTIC AGENT; RISPERIDONE;

AGED; ALZHEIMER DISEASE; ARTICLE; AUDITORY HALLUCINATION; COGNITIVE DEFECT; COLUMBIA UNIVERSITY SCALE FOR PSYCHOPATHOLOGY IN ALZHEIMER DISEASE; CONTROLLED STUDY; DELUSION; DELUSIONAL MISIDENTIFICATION; DIFFERENTIAL DIAGNOSIS; DIFFUSE LEWY BODY DISEASE; DISEASE COURSE; FEMALE; HALLUCINATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHIATRIC INVENTORY; NEUROPSYCHOLOGICAL TEST; PARANOIA; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; QUESTIONNAIRE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; VISUAL HALLUCINATION; VISUAL ILLUSION; VISUAL STIMULATION; COLUMBIA UNIVERSITY SCALE FOR PSYCHOPATHOLOGY IN ALZHEIMERS DISEASE; CORRELATIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; FUNCTIONAL DISEASE; GERIATRIC PATIENT; GERONTOPSYCHIATRY; MENTAL DETERIORATION; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; NEUROIMAGING; PSYCHIATRIC DIAGNOSIS; PSYCHOPHARMACOTHERAPY; PSYCHOSIS; QUALITATIVE RESEARCH; QUANTITATIVE STUDY; SENSITIVITY AND SPECIFICITY;

ALZHEIMER DISEASE; DIAGNOSIS, DIFFERENTIAL; EVALUATION STUDIES AS TOPIC; HUMANS; LEWY BODY DISEASE; NEUROPSYCHOLOGICAL TESTS; PSYCHOMETRICS; QUALITATIVE RESEARCH; REPRODUCIBILITY OF RESULTS;

EID: 84893721625     PISSN: 10416102     EISSN: 1741203X     Source Type: Journal    
DOI: 10.1017/S1041610213002068     Document Type: Article

References (30)

1. Aarsland, D. et al. (2007). Neuropsychiatric symptoms in patients with Parkinson's disease and dementia: Frequency, profile and associated caregiver stress. Journal of Neurology Neurosurgery and Psychiatry, 78, 36-42
2. Auning, E. et al. (2011). Early and presenting symptoms of dementia with Lewy bodies. Dementia and Geriatric Cognitive Disorders, 32, 202-208
3. Ballard, C. G., Lowery, K., Harrison, R. and McKeith, I. G. (1996). Non-Cognitive symptoms in Lewy body dementia. In R. H. Perry, I. G. McKeith and E. K. Perry (eds.), Dementia with Lewy Bodies (pp. 67-84). Cambridge, UK: Cambridge University Press
4. Ballard, C. G., O'Brien, J. T., Swann, A. G., Thompson, P., Neill, D. and McKeith, I. G. (2001). The natural history of psychosis and depression in dementia with Lewy bodies and Alzheimer's disease: Persistence and new cases over 1-year follow-up. Journal of Clinical Psychiatry, 62, 46-49
5. Ballard, C. G. et al. (1995). The prevalence and phenomenology of psychotic symptoms in dementia sufferers. International Journal of Geriatric Psychiatry, 10, 477-485
6. Ballard, C. G. et al. (1999). Psychiatric morbidity in dementia with Lewy bodies: A prospective clinical and neuropathological comparative study with Alzheimer's disease. American Journal of Psychiatry, 156, 1039-1045
7. Böhm, P., Peña-Casanova, J., Aguilar, M., Hernandez, G., Sol, J. M. and Blesa, R. (1998). Clinical validity and utility of the interview for deterioration of daily living in dementia for Spanish-speaking communities NORMACODEM Group. International Psychogeriatrics, 10, 261-270
8. Burns, A., Jacoby, R. and Levy, R. (1990). Psychiatric phenomena in Alzheimer's disease. I: Disorders of thought content. British Journal of Psychiatry, 157, 72-76
9. Cummings, J. L., Mega, M., Gray, K., Rosenberg-Thompson, S., Carusi, D. A. and Gornbein, J. (1994). The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia. Neurology, 44, 2308-2314
10. Del Ser, T., McKetih, I., Anand, R., Cicin-Sain, A., Ferrara, R. and Spiegel, R. (2000). Dementia with Lewy bodies: Findings from an international multicentre study. International Journal of Geriatric Psychiatry, 15, 1034-1045
11. Devanand, D. et al. (1992). The Columbia University Scale for Psychopathology in Alzheimer's disease. Archives of Neurology, 49, 371-376
12. Engelborghs, S. et al. (2005). Neuropsychiatric symptoms of dementia: Cross-sectional analysis from a prospective, longitudinal Belgian study. International Journal of Geriatric Psychiatry, 20, 1028-1037
13. Fazekas, F., Chawluk, J. B., Alavi, A., Hurtig, H. I. and Zimmerman, R. A. (1987). MR signal abnormalities at 1.5 T in Alzheimeŕs dementia and normal aging. American Journal of Roentgenology, 149, 351-358
14. Ferman, T. J. et al. (2004). DLB fluctuations: Specific features that reliably differentiate DLB from AD and normal aging. Neurology, 62, 181-187
15. Folstein, F. E., Folstein, S. E. and McHugh, P. R. (1975). Mini-mental state. A practical method for grading the cognitive state of patients for the clinicians. Journal of Psychiatric Research, 12, 189-198
16. Hirono, N. et al. (1999). Distinctive neurobehavioral features among neurodegenerative dementias. Journal of Neuropsychiatry and Clinical Neurosciences, 11, 498-503
17. Lyketsos, C. G., Steinberg, M., Tschanz, J. T., Norton, M. C., Steffens, D. C. and Breitner, J. C. S. (2000).Mental and behavioural disturbances in dementia: Findings form Cache County Study in Memory and Aging. American Journal of Psychiatry, 157, 708-714
18. McKeith, I. G. (2002). Dementia with Lewy bodies. British Journal of Psychiatry, 180, 144-147
19. McKeith, I. G. et al. (1996). Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy body diseases (DLB): Report of the consortium on DLB international workshop. Neurology, 47, 1113-1124
20. McKeith, I. G. et al. (2005). Diagnosis and management of dementia with Lewy bodies. Third report of the DLB consortium. Neurology, 65, 1863-1872
21. McKeith, I. et al. (2007). Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in the diagnosis of dementia with Lewy bodies: A phase III, multicenter study. Lancet Neurology 6, 305-313
22. McKhann, G. et al. (1984). Clinical diagnosis of Alzheimer's disease report of the NINCDS-ADRA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology, 34, 939-944
23. National Institute for Clinical Excellence (March 2011).Donepezil, Galantamine, Rivastigmine and Memantine for the Treatment of Alzheimer's Disease. Technology appraisal guidance 217. Review of NICE technology appraisal guidance 111. London: NICE
24. O'Brien, J. T. et al. (2004). Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies. Archives of Neurology, 61, 919-925
25. Rockwell, E., Choure, J., Galasko, D., Olichney, J. and Jeste, D. V. (2000). Psychopathology at initial diagnosis in dementia with Lewy bodies versus Alzheimer's disease: Comparison of matched groups with autopsy-Confirmed diagnoses. International Journal of Geriatric Psychiatry, 15, 819-823
26. Stavitsky, K. et al. (2006). The progression of cognition, psychiatric symptoms, and functional abilities in dementia with Lewy bodies and Alzheimer's disease. Archives of Neurology, 63, 1450-1456
27. Teunisse, S., Derix, M. M. and Crevel, H. (1991).Assessing the severity of dementia. Patient and caregiver. Archives of Neurology, 4, 274-277
28. Tiraboschi, P., Salmon, D. P., Hansen, L. A., Hofstetter, R. C., Thal, L. J. and Corey-Bloom, J. (2006). What best differentiates Lewy body from Alzheimer's disease in early stage dementia? Brain, 129, 729-735
29. Walker, Z. et al. (2007). Dementia with Lewy bodies: A comparison of clinical diagnosis, FP-CIT single photon emission computed tomography imaging and autopsy. Journal of Neurology, Neurosurgery Psychiatry with Practical Neurology, 78, 1176-1181
30. Weiner, M. F. et al. (1996). Alzheimer's disease and its Lewy body variant: A clinical analysis of postmorten verified cases. American Journal of Psychiatry, 153, 1269-1273