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Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 3, 2014, Pages 845-849

Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists

(11) Joshi, Pramod a Anderson, Corey a Binch, Hayley a Hadida, Sabine a Yoo, Sanghee a Bergeron, Danielle a Decker, Caroline a Terhaar, Ernst a Moore, Jonathan a Garcia Guzman, Miguel b Termin, Andreas a

a VERTEX PHARMACEUTICALS (United States)

b Aspyrian Therapeutics Inc (United States)

Author keywords

CGRP antagonists; Migraine; Thiazolidinone

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; OLCEGEPANT; TELCAGEPANT; THIAZOLIDINE DERIVATIVE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG IDENTIFICATION; DRUG POTENCY; IC 50; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; STEREOCHEMISTRY;

CGRP ANTAGONISTS; MIGRAINE; THIAZOLIDINONE;

ANIMALS; AZEPINES; CALCITONIN GENE-RELATED PEPTIDE; DIPEPTIDES; HUMANS; IMIDAZOLES; INHIBITORY CONCENTRATION 50; MIGRAINE DISORDERS; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; PROTEIN BINDING; QUINAZOLINES; QUINAZOLINONES; RATS; RECEPTORS, CALCITONIN GENE-RELATED PEPTIDE; THIAZOLIDINEDIONES; UREA;

EID: 84893709298 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2013.12.089 Document Type: Article

Times cited : (20)

References (12)

1
- 1542346238
- references therein
- J. Olesen, H.-C. Diener, I.W. Husstedt, P.J. Goadsby, D. Hall, U. Meier, S. Pollentier, and L.M.N. Lesko Engl. J. Med. 350 2004 1104 and references therein
- (2004) Engl. J. Med. , vol.350 , pp. 1104
- Olesen, J.¹ Diener, H.-C.² Husstedt, I.W.³ Goadsby, P.J.⁴ Hall, D.⁵ Meier, U.⁶ Pollentier, S.⁷ Lesko, L.M.N.⁸

2
- 0021997471
- S.D. Brain, T.J. Williams, J.R. Tippins, H.R. Morris, and I. MacIntyre Nature 313 1985 54
- (1985) Nature , vol.313 , pp. 54
- Brain, S.D.¹ Williams, T.J.² Tippins, J.R.³ Morris, H.R.⁴ Macintyre, I.⁵

3
- 24944552764
- K. Rudolf, W. Eberlein, W. Engel, H. Pieper, M. Entzeroth, G. Halleymayer, and H. Doods J. Med. Chem. 48 2005 5921
- (2005) J. Med. Chem. , vol.48 , pp. 5921
- Rudolf, K.¹ Eberlein, W.² Engel, W.³ Pieper, H.⁴ Entzeroth, M.⁵ Halleymayer, G.⁶ Doods, H.⁷

4
- 33751214181
- M. Shimizu, K. Hata, H. Takaoka, K. Kanazawa, T. Shinke, H. Matsumoto, S. Watanabe, R. Yoshikawa, H. Masai, Y. Miyamoto, H. Akita, and M. Yokoyama Int. J. Cardiol. 114 2007 188
- (2007) Int. J. Cardiol. , vol.114 , pp. 188
- Shimizu, M.¹ Hata, K.² Takaoka, H.³ Kanazawa, K.⁴ Shinke, T.⁵ Matsumoto, H.⁶ Watanabe, S.⁷ Yoshikawa, R.⁸ Masai, H.⁹ Miyamoto, Y.¹⁰ Akita, H.¹¹ Yokoyama, M.¹²

5
- 33645886051
- T.M. Williams, C.A. Stump, D.N. Nguyen, A.G. Quigley, I.M. Bell, S.N. Gallicchio, C. Blair Zartman, B-L. Wan, K.D. Penna, P. Kunapuli, S.A. Kane, K.S. Koblan, S.D. Mosser, R.Z. Rutledge, C. Salvatore, J.F. Fay, J.P. Vacca, and S.L. Graham Biorg. Med Chem. Lett. 16 2006 2595
- (2006) Biorg. Med Chem. Lett. , vol.16 , pp. 2595
- Williams, T.M.¹ Stump, C.A.² Nguyen, D.N.³ Quigley, A.G.⁴ Bell, I.M.⁵ Gallicchio, S.N.⁶ Blair Zartman, C.⁷ Wan, B.-L.⁸ Penna, K.D.⁹ Kunapuli, P.¹⁰ Kane, S.A.¹¹ Koblan, K.S.¹² Mosser, S.D.¹³ Rutledge, R.Z.¹⁴ Salvatore, C.¹⁵ Fay, J.F.¹⁶ Vacca, J.P.¹⁷ Graham, S.L.¹⁸

6
- 33747336251
- C.S. Burgey, C.A. Stump, D.M. Nguyen, J.Z. Deng, A.G. Quigley, B.R. Norton, I.M. Bell, S.D. Mosser, C.A. Salvatore, R.Z. Rutledge, S.A. Kane, K.S. Koblan, J.P. Vacca, S.L. Graham, and T.M. Williams Biorg. Med Chem. Lett. 16 2006 5052
- (2006) Biorg. Med. Chem. Lett. , vol.16 , pp. 5052
- Burgey, C.S.¹ Stump, C.A.² Nguyen, D.M.³ Deng, J.Z.⁴ Quigley, A.G.⁵ Norton, B.R.⁶ Bell, I.M.⁷ Mosser, S.D.⁸ Salvatore, C.A.⁹ Rutledge, R.Z.¹⁰ Kane, S.A.¹¹ Koblan, K.S.¹² Vacca, J.P.¹³ Graham, S.L.¹⁴ Williams, T.M.¹⁵

7
- 34547533721
- A.W. Shaw, D.V. Paone, D.M. Nguyen, C.A. Stump, C.S. Burgey, S.D. Mosser, C.S. Salvatore, R.Z. Rutledge, S.A. Kane, K.S. Koblan, S.L. Graham, J.P. Vacca, and T.M. Williams Bioorg. Med. Chem. Lett. 17 2007 4795
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 4795
- Shaw, A.W.¹ Paone, D.V.² Nguyen, D.M.³ Stump, C.A.⁴ Burgey, C.S.⁵ Mosser, S.D.⁶ Salvatore, C.S.⁷ Rutledge, R.Z.⁸ Kane, S.A.⁹ Koblan, K.S.¹⁰ Graham, S.L.¹¹ Vacca, J.P.¹² Williams, T.M.¹³

8
- 0032472195
- 2) and 10 μL of CCF4/AM was added across plate. The plate was incubated for additional 2 hrs at room temperature and read at tcPR, a Vertex proprietary fluorescence plate reader.
- (1998) Science , vol.279 , pp. 84
- Zlokarnik, G.¹ Negulescu . P, A.² Knapp . T, E.³ Mere, L.⁴ Burres, N.⁵ Feng, L.⁶ Whitney, M.⁷ Roemer, K.⁸ Tsien . R, Y.⁹

9
- 77956336134
- E. ter Haar, C.M. Koth, N. Abdul-Manan, L. Swenson, J. Coll, J.A. Lippke, M. Garcia-Guzman, and J.M. Moore Structure 18 9 2010 1083 1093
- (2010) Structure , vol.18 , Issue.9 , pp. 1083-1093
- Ter Haar, E.¹ Koth, C.M.² Abdul-Manan, N.³ Swenson, L.⁴ Coll, J.⁵ Lippke, J.A.⁶ Garcia-Guzman, M.⁷ Moore, J.M.⁸

10
- 0015861774
- Y. Cheng, and W.H. Prusoff Biochem. Pharmacol. 22 1973 3099
- (1973) Biochem. Pharmacol. , vol.22 , pp. 3099
- Cheng, Y.¹ Prusoff, W.H.²

11
- 0031682591
- T. Shiraiwa, M. Ohkubo, M. Kubo, H. Miyazaki, M. Takehata, H. Izawa, K. Nakagawa, and H. Kurokawa Chem. Pharm. Bull. 46 1998 1364
- (1998) Chem. Pharm. Bull. , vol.46 , pp. 1364
- Shiraiwa, T.¹ Ohkubo, M.² Kubo, M.³ Miyazaki, H.⁴ Takehata, M.⁵ Izawa, H.⁶ Nakagawa, K.⁷ Kurokawa, H.⁸

12
- 33845937770
- S.A. Hitchcock, and L.D. Pennington J. Med. Chem. 49 26 2006 7559
- (2006) J. Med. Chem. , vol.49 , Issue.26 , pp. 7559
- Hitchcock, S.A.¹ Pennington, L.D.²

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