Intravenous thrombolysis in ischemic stroke with unknown onset using CT perfusion

Acta Neurologica Scandinavica

Volumn 129, Issue 3, 2014, Pages 178-183

  Cortijo, E ^a   Garcia Bermejo P ^a   Calleja, A I ^a   Perez Fernandez S ^a   Gomez R ^a   del Monte, J M ^a   Reyes, J ^a   Arenillas, J F ^a  

^a HOSPITAL CLÍNICO UNIVERSITARIO DE VALLADOLID   (Spain)

Author keywords

Intravenous thrombolysis; Ischemic stroke; Perfusion CT; Wake up stroke

Indexed keywords

ALTEPLASE;

ADULT; ARTICLE; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CLINICAL ARTICLE; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE DURATION; FEMALE; FIBRINOLYTIC THERAPY; FUNCTIONAL STATUS; HUMAN; MALE; MIDDLE AGED; MIDDLE CEREBRAL ARTERY OCCLUSION; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NEUROIMAGING; OUTCOME ASSESSMENT; PROSPECTIVE STUDY; RECANALIZATION; STROKE PATIENT; TIME TO TREATMENT; VERY ELDERLY;

INTRAVENOUS THROMBOLYSIS; ISCHEMIC STROKE; PERFUSION CT; WAKE-UP STROKE;

ADMINISTRATION, INTRAVENOUS; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; THROMBOLYTIC THERAPY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84893669783     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/ane.12160     Document Type: Article

References (25)

1. Hacke W, Kaste M, Bluhmki E et al. Thrombolysis with Alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008;359:1317-29.
2. Fink JN, Kumar S, Horkan C et al. The stroke patient who woke up: clinical and radiological features, including diffusion and perfusion MR. Stroke 2002;33:988-93.
3. Kellier KD, Hamptom JL, Guadagno JV et al. Perfusion CT helps decision making for thrombolysis when there is no clear time of onset. J Neurol Neurosurg Psychiatry 2006;77:417-9.
4. Serena J, Davalos A, Segura T, Mostacero E, Castillo J. Stroke on awakening: looking for a more rational management. Cerebrovasc Dis 2003;16:128-33.
5. Barreto AD, Martin-Schild S, Hallevi H et al. Thrombolytic therapy for patients who wake up with stroke. Stroke 2009;40:827-32.
6. Muller JE. Circadian variation in cardiovascular events. Am J Hypertens 1999;12:35S-42S.
7. Wahlgren N, Ahmed N, Dávalos A et al. Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SIST-MOST): an observational study. Lancet 2007;369:275-82.
8. Adams HP Jr, Bendixen BH, Kappelle LJ et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. Toast. Trial of org 10172 in acute stroke treatment. Stroke 1993;24:35-41.
9. García-Bermejo P, Calleja AI, Pérez-Fernández S et al. Perfusion computed tomography guided intravenous thrombolysis for acute ischemic stroke beyond 4.5 hours: a case-control study. Cerebrovasc Dis 2012;34:31-7.
10. Barber PA, Demchuk AM, Zhang J, Buchan AM; for the ASPECTS Study Group. The validity and reliability of a novel quantitative CT score in predicting outcome in hyperacute stroke prior to thrombolytic therapy. Lancet 2000;355:1670-4.
11. Wintermark M, Meuli R, Browaeys P et al. Comparison of CT perfusion and angiography and MRI in selecting stroke patient for acute treatment. Neurology 2007;68:694-7.
12. Wintermark M, Reichhart M, Cuisenaire O et al. Comparison of admission perfusion computed tomography and qualitative diffusion and perfusion-weight magnetic resonance imaging to acute stroke patients. Stroke 2002;33:2025-31.
13. Todo K, Moriwaki H, Saito K, Tanaka M, Oe H, Naritomi H. Early CT findings in unknown-onset and wake-up strokes. Cerebrovasc Dis 2006;21:367-71.
14. Huisa NB, Raman R, Ernstrom K et al. Alberta Stroke Program Early CT Score (ASPECTS) in patients with wake-up stroke. J Stroke Cerebrovasc Dis 2010;19:475-9.
15. Adams HP, Effron MB, Torner J et al. Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of an International Phase III Trial: Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II). Stroke 2008;39:87-99.
16. Adams HP Jr, Leira EC, Torner JC et al. Treating patients with "wake-up" stroke: the Experience of the AbESTT-II Trial. Stroke 2008;39:3277-82.
17. Albers GW, Thijs VN, Wechster L et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) Study. Ann Neurol 2006;60:508-17.
18. Davis SM, Donnan GA, Parsons MW et al. Effects of alteplase beyond 3 hour after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo- controlled randomised trial. Lancet Neurol 2008;7:299-309.
19. Kondziella D, Cortsen M, Eskesen V et al. Update on acute endovascular and surgical stroke treatment. Acta Neurol Scand 2013;127:1-9.
20. Strbian D, Soinne L, Sairanen T et al. Intravenous thrombolysis in ischemic stroke patients with isolated homonymous hemianopia. Acta Neurol Scand 2012;126:e17-9.
21. Kozera G, Chwojnicki K, Gójska-Grymajlo A, Gasecki D, Schminke U, Nyka WM; Pomeranian Stroke Register collaborators. Pre-hospital delays and intravenous thrombolysis in urban and rural areas. Acta Neurol Scand 2012;126:171-7.
22. Campbell BC, Christensen S, Levi CR et al. Cerebral blood flow is the optimal CT perfusion parameter for assessing infarct core. Stroke 2011;42:435-40.
23. Kamalian S, Kamalian S, Maas MB et al. CT cerebral blood flow maps optimally correlate with admission diffusion-weighted imaging in acute stroke but thresholds vary by postprocessing platform. Stroke 2011;42:1923-8.
24. Zeber-Weber O, Kracht L, Auer F, Neveling M, Heiss WD. Perfusion Computed Tomography in Ischemic Stroke Compared to 15O-water-PET. Cerebrovasc Dis 2012;33(Suppl 2):1-944. Abstract, European Stroke Conference, Lisbon, May 2012
25. Campbell BC, Christensen S, Foster SJ et al. Visual assessment of perfusion-diffusion mismatch is inadequate to select patients for thrombolysis. Cerebrovasc Dis 2010;29:592-6.