Creating polymer hydrogel microfibres with internal alignment via electrical and mechanical stretching

Biomaterials

Volumn 35, Issue 10, 2014, Pages 3243-3251

  Zhang, Shuming ^a,b   Liu, Xi ^a,c   Barreto Ortiz, Sebastian F ^a,b   Yu, Yixuan ^d   Ginn, Brian P ^a,b   DeSantis, Nicholas A ^a   Hutton, Daphne L ^a,b,e   Grayson, Warren L ^a,b,e   Cui, Fu Zhai ^c   Korgel, Brian A ^d   Gerecht, Sharon ^a,b   Mao, Hai Quan ^a,b  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c TSINGHUA UNIVERSITY   (China)

^d The University of Texas at Austin   (United States)

^e JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alginate; Fibrin; Hyaluronic acid; Hydrogel; Microstructure

Indexed keywords

CELLULAR ORGANIZATION; EXTRACELLULAR MATRICES; FIBRIN; ISOTROPIC STRUCTURE; MECHANICAL STRETCHING; ORGANIC SOLVENT-FREE; PHYSICOCHEMICAL PROPERTY; PROCESSING CONDITION;

ALGINATE; ALIGNMENT; BIOMECHANICS; CELL CULTURE; HYALURONIC ACID; MECHANICAL PROPERTIES; MICROSTRUCTURE; ORGANIC ACIDS; TISSUE;

HYDROGELS;

ALGINIC ACID; FIBRIN; GELATIN; HYALURONIC ACID; ORGANIC SOLVENT; POLYMER;

AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTROSPINNING; HUMAN; HUMAN CELL; HYDROGEL; MECHANICS; PHYSICAL CHEMISTRY; POROSITY; PRIORITY JOURNAL; STRETCHING; SURFACE PROPERTY; TOPOGRAPHY; WATER CONTENT;

ALGINATE; FIBRIN; HYALURONIC ACID; HYDROGEL; MICROSTRUCTURE;

BIOCOMPATIBLE MATERIALS; CELLULAR MICROENVIRONMENT; HYDROGELS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, FLUORESCENCE; POLYMERS; SCATTERING, SMALL ANGLE;

EID: 84893643200     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.081     Document Type: Article

References (40)

1. Seliktar D. Designing cell-compatible hydrogels for biomedical applications. Science 2012, 336:1124-1128.
2. Burdick J.A., Anseth K.S. Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials 2002, 23:4315-4323.
3. Williams C.G., Kim T.K., Taboas A., Malik A., Manson P., Elisseeff J. In vitro chondrogenesis of bone marrow-derived mesenchymal stem cells in a photopolymerizing hydrogel. Tissue Eng 2003, 9:679-688.
4. Silva G.A., Czeisler C., Niece K.L., Beniash E., Harrington D.A., Kessler J.A., et al. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 2004, 303:1352-1355.
5. Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689.
6. Discher D.E., Janmey P., Wang Y.-l. Tissue cells feel and respond to the stiffness of their substrate. Science 2005, 310:1139-1143.
7. Lutolf M.P., Lauer-Fields J.L., Schmoekel H.G., Metters A.T., Weber F.E., Fields G.B., et al. Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: engineering cell-invasion characteristics. Proc Natl Acad Sci U S A 2003, 100:5413-5418.
8. Dalsin J.L., Hu B.H., Lee B.P., Messersmith P.B. Mussel adhesive protein mimetic polymers for the preparation of nonfouling surfaces. J Am Chem Soc 2003, 125:4253-4258.
9. Martino M.M., Mochizuki M., Rothenfluh D.A., Rempel S.A., Hubbell J.A., Barker T.H. Controlling integrin specificity and stem cell differentiation in 2D and 3D environments through regulation of fibronectin domain stability. Biomaterials 2009, 30:1089-1097.
10. Yang F., Murugan R., Wang S., Ramakrishna S. Electrospinning of nano/micro scale poly(l-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 2005, 26:2603-2610.
11. Bettinger C.J., Langer R., Borenstein J.T. Engineering substrate topography at the micro- and nanoscale to control cell function. Angew Chem Int Ed 2009, 48:5406-5415.
12. Chew S.Y., Mi R., Hoke A., Leong K.W. The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials 2008, 29:653-661.
13. Aubin H., Nichol J.W., Hutson C.B., Bae H., Sieminski A.L., Cropek D.M., et al. Directed 3D cell alignment and elongation in microengineered hydrogels. Biomaterials 2010, 31:6941-6951.
14. Lim S.H., Mao H.Q. Electrospun scaffolds for stem cell engineering. Adv Drug Deliv Rev 2009, 61:1084-1096.
15. Ji Y., Ghosh K., Shu X.Z., Li B., Sokolov J.C., Prestwich G.D., et al. Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds. Biomaterials 2006, 27:3782-3792.
16. Coburn J., Gibson M., Bandalini P.A., Laird C., Mao H.Q., Moroni L., et al. Biomimetics of the extracellular matrix: an integrated three-dimensional fiber-hydrogel composite for cartilage tissue engineering. Smart Struct Syst 2011, 7:213-222.
17. Kang E., Choi Y.Y., Chae S.K., Moon J.H., Chang J.Y., Lee S.H. Microfluidic spinning of flat alginate fibers with grooves for cell-aligning scaffolds. Adv Mater 2012, 24:4271-4277.
18. Kang E., Jeong G.S., Choi Y.Y., Lee K.H., Khademhosseini A., Lee S.H. Digitally tunable physicochemical coding of material composition and topography in continuous microfibres. Nat Mater 2011, 10:877-883.
19. Zhang S., Greenfield M.A., Mata A., Palmer L.C., Bitton R., Mantei J.R., et al. A self-assembly pathway to aligned monodomain gels. Nat Mater 2010, 9:594-601.
20. Ji Y., Ghosh K., Li B., Sokolov J.C., Clark R.A., Rafailovich M.H. Dual-syringe reactive electrospinning of cross-linked hyaluronic acid hydrogel nanofibers for tissue engineering applications. Macromol Biosci 2006, 6:811-817.
21. Nichol J.W., Koshy S.T., Bae H., Hwang C.M., Yamanlar S., Khademhosseini A. Cell-laden microengineered gelatin methacrylate hydrogels. Biomaterials 2010, 31:5536-5544.
22. Shu X.Z., Liu Y., Palumbo F.S., Luo Y., Prestwich G.D. In situ crosslinkable hyaluronan hydrogels for tissue engineering. Biomaterials 2004, 25:1339-1348.
23. Potter K., Balcom B.J., Carpenter T.A., Hall L.D. The gelation of sodium alginate with calcium ions studied by magnetic resonance imaging (MRI). Carbohydr Res 1994, 257:117-126.
24. Cornwell K.G., Pins G.D. Enhanced proliferation and migration of fibroblasts on the surface of fibroblast growth factor-2-loaded fibrin microthreads. Tissue Eng Part A 2010, 16:3669-3677.
25. Cornwell K.G., Pins G.D. Discrete crosslinked fibrin microthread scaffolds for tissue regeneration. J Biomed Mater Res A 2007, 82:104-112.
26. Sun J.Y., Zhao X., Illeperuma W.R., Chaudhuri O., Oh K.H., Mooney D.J., et al. Highly stretchable and tough hydrogels. Nature 2012, 489:133-136.
27. Onoe H., Okitsu T., Itou A., Kato-Negishi M., Gojo R., Kiriya D., et al. Metre-long cell-laden microfibres exhibit tissue morphologies and functions. Nat Mater 2013, 12:584-590.
28. Ingram D.A., Mead L.E., Tanaka H., Meade V., Fenoglio A., Mortell K., et al. Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood. Blood 2004, 104:2752-2760.
29. Bellan L.M., Craighead H.G. Molecular orientation in individual electrospun nanofibers measured via polarized Raman spectroscopy. Polymer 2008, 49:3125-3129.
30. Fennessey S.F., Farris R.J. Fabrication of aligned and molecularly oriented electrospun polyacrylonitrile nanofibers and the mechanical behavior of their twisted yarns. Polymer 2004, 45:4217-4225.
31. Kongkhlang T., Tashiro K., Kotaki M., Chirachanchai S. Electrospinning as a new technique to control the crystal morphology and molecular orientation of polyoxymethylene nanofibers. J Am Chem Soc 2008, 130:15460-15466.
32. Larson R., Mead D. The Ericksen number and Deborah number cascades in sheared polymeric nematics. Liq Cryst 1993, 15:151-169.
33. Inai R., Kotaki M., Ramakrishna S. Structure and properties of electrospun PLLA single nanofibres. Nanotechnology 2005, 16:208-213.
34. Zong X., Kim K., Fang D., Ran S., Hsiao B.S., Chu B. Structure and process relationship of electrospun bioabsorbable nanofiber membranes. Polymer 2002, 43:4403-4412.
35. Moon S., Ryu B.Y., Choi J., Jo B., Farris R.J. The morphology and mechanical properties of sodium alginate based electrospun poly(ethylene oxide) nanofibers. Polym Eng Sci 2009, 49:52-59.
36. Angammana C.J., Jayaram S.H. Analysis of the effects of solution conductivity on electrospinning process and fiber morphology. IEEE Trans Ind Appl 2011, 47:1109-1117.
37. Wagner C., Amarouchene Y., Bonn D., Eggers J. Droplet detachment and satellite bead formation in viscoelastic fluids. Phys Rev Lett 2005, 95:164504.
38. Tirtaatmadja V., McKinley G.H., Cooper-White J.J. Drop formation and breakup of low viscosity elastic fluids: effects of molecular weight and concentration. Phys Fluids 2006, 18:043101.
39. Reneker D.H., Yarin A.L., Fong H., Koombhongse S. Bending instability of electrically charged liquid jets of polymer solutions in electrospinning. J Appl Phys 2000, 87:4531.
40. Chae S.K., Kang E., Khademhosseini A., Lee S.H. Micro/nanometer-scale fiber with highly ordered structures by mimicking the spinning process of silkworm. Adv Mater 2013, 25:3071-3078.