Digitally tunable physicochemical coding of material composition and topography in continuous microfibres

Nature Materials

Volumn 10, Issue 11, 2011, Pages 877-883

  Kang, Edward ^a   Jeong, Gi Seok ^a   Choi, Yoon Young ^a   Lee, Kwang Ho ^a,b,f   Khademhosseini, Ali ^c,d,e   Lee, Sang Hoon ^a  

^a Korea University   (South Korea)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e HARVARD UNIVERSITY   (United States)

^f Kangwon National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL ENGINEERING; DIGITAL MICROFLUIDICS; FUNCTIONAL MATERIALS; MICROFLUIDICS;

CHEMICAL COMPOSITIONS; CHEMICAL FEATURES; COMPLEX MATERIALS; ENCAPSULATED CELL; MATERIAL COMPOSITIONS; MICRO FLUIDIC SYSTEM; TISSUE ENGINEERING APPLICATIONS; TOPOGRAPHICAL PROPERTIES;

TISSUE ENGINEERING;

ANIMAL; ARTICLE; CHEMISTRY; COCULTURE; INSTRUMENTATION; METHODOLOGY; MICROFLUIDICS; SILK; SPIDER; TISSUE ENGINEERING;

ANIMALS; COCULTURE TECHNIQUES; MICROFLUIDICS; SILK; SPIDERS; TISSUE ENGINEERING;

EID: 80054956005     PISSN: 14761122     EISSN: 14764660     Source Type: Journal    
DOI: 10.1038/nmat3108     Document Type: Article

References (26)

1. Daher, R. J., Chahine, N. O., Greenberg, A. S., Sgaglione, N. A. & Grande, D. A. New methods to diagnose and treat cartilage degeneration. Nature Rev. Rheumatol. 5, 599-607 (2009).
2. Silva, G. A. et al. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 303, 1352-1355 (2004). (Pubitemid 38269424)
3. Moutos, F. T., Freed, L. E. & Guilak, F. A biomimetic three-dimensional woven composite scaffold for functional tissue engineering of cartilage. Nature Mater. 6, 162-167 (2007). (Pubitemid 46197652)
4. Shi, J. J., Votruba, A. R., Farokhzad, O. C. & Langer, R. Nanotechnology in drug delivery and tissue engineering: From discovery to applications. Nano Lett. 10, 3223-3230 (2010).
5. Greiner, A. & Wendorff, J. H. Electrospinning: A fascinating method for the preparation of ultrathin fibres. Angew. Chem. Int. Ed. 46, 5670-5703 (2007). (Pubitemid 47172190)
6. Sill, T. J. & von Recum, H. A. Electro spinning: Applications in drug delivery and tissue engineering. Biomaterials 29, 1989-2006 (2008).
7. Hu, M. et al. Hydrodynamic spinning of hydrogel fibers. Biomaterials 31, 863-869 (2010).
8. Rammensee, S., Slotta, U., Scheibel, T. & Bausch, A. R. Assembly mechanism of recombinant spider silk proteins. Proc. Natl Acad. Sci. USA 105, 6590-6595 (2008). (Pubitemid 351754551)
9. Pregibon, D. C., Toner, M. & Doyle, P. S. Multifunctional encoded particles for high-throughput biomolecule analysis. Science 315, 1393-1396 (2007). (Pubitemid 46399544)
10. Xu, Q. B. et al. Preparation of monodisperse biodegradable polymer microparticles using a microfluidic flow-focusing device for controlled drug delivery. Small 5, 1575-1581 (2009).
11. Breslauer, D. N., Muller, S. J. & Lee, L. P. Generation of monodisperse silk microspheres prepared with microfluidics. Biomacromolecules 11, 643-647 (2010).
12. Chung, S. E., Park, W., Shin, S., Lee, S. A. & Kwon, S. Guided and fluidic self-assembly of microstructures using railed microfluidic channels. Nature Mater. 7, 581-587 (2008).
13. Mandal, S., Bhaskar, S. & Lahann, J. Micropatterned fiber scaffolds for spatially controlled cell adhesion. Macromol. Rapid Commun. 30, 1638-1644 (2009).
14. Bhaskar, S., Hitt, J., Chang, S. W. L. & Lahann, J. Multicompartmental microcylinders. Angew. Chem. Int. Ed. 48, 4589-4593 (2009).
15. Jeong, W. et al. Hydrodynamic microfabrication via ̀on the fly' photopolymerization of microscale fibers and tubes. Lab Chip 4, 576-580 (2004). (Pubitemid 39657909)
16. Breslauer, D. N., Lee, L. P. & Muller, S. J. Simulation of flow in the silk gland. Biomacromolecules 10, 49-57 (2009).
17. Kang, E., Shin, S. J., Lee, K. H. & Lee, S. H. Novel PDMS cylindrical channels that generate coaxial flow, and application to fabrication of microfibers and particles. Lab Chip 10, 1856-1861 (2010).
18. Vollrath, F. Biology of spider silk. Int. J. Biol. Macromol. 24, 81-88 (1999). (Pubitemid 29227189)
19. Vollrath, F. & Knight, D. P. Liquid crystalline spinning of spider silk. Nature 410, 541-548 (2001). (Pubitemid 32267190)
20. Shin, S. et al. ̀̀On the fly" continuous generation of alginate fibers using a microfluidic device. Langmuir 23, 9104-9108 (2007). (Pubitemid 47294331)
21. Kang, E., Lee, D. H., Kim, C. B., Yoo, S. J. & Lee, S. H. A hemispherical microfluidic channel for the trapping and passive dissipation of microbubbles. J. Micromech. Microeng. 20, 045009 (2010).
22. Hwang, C. M., Khademhosseini, A., Park, Y., Sun, K. & Lee, S. H. Microfluidic chip-based fabrication of PLGA microfiber scaffolds for tissue engineering. Langmuir 24, 6845-6851 (2008).
23. Jung, J. H., Choi, C. H., Chung, S., Chung, Y. M. & Lee, C. S. Microfluidic synthesis of a cell adhesive Janus polyurethane microfiber. Lab Chip 9, 2596-2602 (2009).
24. Zheng, Y. M. et al. Directional water collection on wetted spider silk. Nature 463, 640-643 (2010).
25. Blackledge, T. A. & Hayashi, C. Y. Silken toolkits: Biomechanics of silk fibers spun by the orb web spider Argiope argentata (Fabricius 1775). J. Exp. Biol. 209, 2452-2461 (2006). (Pubitemid 44212835)
26. Renneberg, R., Sonomoto, K., Katoh, S. & Tanaka, A. Oxygen diffusivity of synthetic gels derived from prepolymers. Appl. Microbiol. Biot. 28, 1-7 (1988).