-
1
-
-
84883610953
-
-
accessed 07/06/2013
-
Dohle GR, Arver S, Bettocchi C, Kliesch S, Punab M, der Ronde W,. EAU guidelines on male hypogonadism. http://www.uroweb.org/gls/pdf/16-Male- Hypogonadism-LR%20II.pdf (accessed 07/06/2013).
-
EAU Guidelines on Male Hypogonadism
-
-
Dohle, G.R.1
Arver, S.2
Bettocchi, C.3
Kliesch, S.4
Punab, M.5
Der Ronde, W.6
-
2
-
-
56249088599
-
Investigation, treatment, and monitoring of late-onset hypogonadism in Males; ISA, ISSAM, EAU, EAA, ASA Recommendation
-
Wang C, Nieschlag E, Swerdloff RS, et al. Investigation, treatment, and monitoring of late-onset hypogonadism in Males; ISA, ISSAM, EAU, EAA, ASA Recommendation. Eur Urol 2009; 55: 121-130.
-
(2009)
Eur Urol
, vol.55
, pp. 121-130
-
-
Wang, C.1
Nieschlag, E.2
Swerdloff, R.S.3
-
3
-
-
77958106876
-
Androgens, health and sexuality
-
Wylie K, Rees M, Hackett G, et al. Androgens, health and sexuality. Maturitas 2010; 67: 275-89.
-
(2010)
Maturitas
, vol.67
, pp. 275-289
-
-
Wylie, K.1
Rees, M.2
Hackett, G.3
-
4
-
-
33751533215
-
Association of specific symptoms and metabolic risk with serum testosterone in order men
-
Zitzmann M, Faber E, Nieschlag E,. Association of specific symptoms and metabolic risk with serum testosterone in order men. J Clin Endocrinol Metab 2006; 91: 4335-43.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 4335-4343
-
-
Zitzmann, M.1
Faber, E.2
Nieschlag, E.3
-
5
-
-
77954414397
-
Identification of late-onset hypogonadism in middle-aged and elderly men
-
for the EMAS Group
-
Wu FW, Tajar A., Beynon JM, et al., for the EMAS Group. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med 2010; 363: 123-136.
-
(2010)
N Engl J Med
, vol.363
, pp. 123-136
-
-
Wu, F.W.1
Tajar, A.2
Beynon, J.M.3
-
6
-
-
84893711717
-
-
accessed 18/5/2013
-
http://Documents/Reports/Diabetes-in-the-UK-2010.pdf (accessed 18/5/2013).
-
-
-
-
7
-
-
8744228132
-
Frequent occurrence of hypogonadotrophic hypogonadism in type 2 diabetes
-
Dhindsa S, Prabhakar S, Sethi M, et al. Frequent occurrence of hypogonadotrophic hypogonadism in type 2 diabetes. J Clin Endocrin Metab 2004; 89: 5462-8.
-
(2004)
J Clin Endocrin Metab
, vol.89
, pp. 5462-5468
-
-
Dhindsa, S.1
Prabhakar, S.2
Sethi, M.3
-
8
-
-
34147104552
-
Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: Correlations with bioavailable testosterone and visceral adiposity
-
Kapoor D, Aldred H, Clark S, et al. Clinical and biochemical assessment of hypogonadism in men with type 2 diabetes: correlations with bioavailable testosterone and visceral adiposity. Diabetes Care 2007; 30: 911-17.
-
(2007)
Diabetes Care
, vol.30
, pp. 911-917
-
-
Kapoor, D.1
Aldred, H.2
Clark, S.3
-
9
-
-
74549224371
-
Biochemical hypogonadism and type 2 diabetes in primary care
-
Hackett G, Cole N, Deshpande A, Popple M, Kennedy D, Wilkinson P,. Biochemical hypogonadism and type 2 diabetes in primary care. Br J Diab Vasc Dis 2009; 9: 216-2315.
-
(2009)
Br J Diab Vasc Dis
, vol.9
, pp. 216-2315
-
-
Hackett, G.1
Cole, N.2
Deshpande, A.3
Popple, M.4
Kennedy, D.5
Wilkinson, P.6
-
10
-
-
84865412199
-
Many men are receiving unnecessary testosterone prescriptions
-
doi: (Published 21 August 2012)
-
Gan E, Pattmann S, Pearce S, Quinton R,. Many men are receiving unnecessary testosterone prescriptions. BMJ 2012; 345: e5469. doi: http://dx.doi.org/10.1136/bmj.e5469 (Published 21 August 2012)
-
(2012)
BMJ
, vol.345
-
-
Gan, E.1
Pattmann, S.2
Pearce, S.3
Quinton, R.4
-
12
-
-
37349118353
-
Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) prospective population study
-
Khaw KT, Dowsett M, Folkerd E, et al. Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) prospective population study. Circulation 2007; 116; 2694-2701.
-
(2007)
Circulation
, vol.116
, pp. 2694-2701
-
-
Khaw, K.T.1
Dowsett, M.2
Folkerd, E.3
-
13
-
-
0036342660
-
Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: The Rotterdam Study
-
Hak AE, Witteman JCM, De Jong FH, et al. Low levels of endogenous androgens increase the risk of atherosclerosis in elderly men: the Rotterdam Study. J Clin Endocrinol Metab 2002; 87: 3632-9.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3632-3639
-
-
Hak, A.E.1
Witteman, J.C.M.2
De Jong, F.H.3
-
14
-
-
33747158767
-
Low serum testosterone and mortality in male veterans
-
Shores MM, Matsumoto AM, Sloan KL, et al. Low serum testosterone and mortality in male veterans. Arch Intern Med 2006; 166: 1660-65.
-
(2006)
Arch Intern Med
, vol.166
, pp. 1660-1665
-
-
Shores, M.M.1
Matsumoto, A.M.2
Sloan, K.L.3
-
15
-
-
67650248724
-
Low serum testosterone and estradiol predict mortality in elderly men
-
Tivesten A, Vandenput L, Labrie F, et al. Low serum testosterone and estradiol predict mortality in elderly men. J Endocrinol Metab 2009; 94: 2482-2488.
-
(2009)
J Endocrinol Metab
, vol.94
, pp. 2482-2488
-
-
Tivesten, A.1
Vandenput, L.2
Labrie, F.3
-
16
-
-
36148989115
-
Relationship between low levels of anabolic hormones and 6 year mortality in older men in the Chianti area
-
Maggi M, Laurentini F, Ceda GP, et al. Relationship between low levels of anabolic hormones and 6 year mortality in older men in the Chianti area. Arch Int Med 2007; 167: 2249-2254.
-
(2007)
Arch Int Med
, vol.167
, pp. 2249-2254
-
-
Maggi, M.1
Laurentini, F.2
Ceda, G.P.3
-
17
-
-
84855509183
-
Low free testosterone predicts mortality from cardiovascular disease but not other causes: The Health in Men Study
-
Hyde Z, Norman P, Flicker L, et al. Low free testosterone predicts mortality from cardiovascular disease but not other causes: The Health in Men Study. J Clin Endocrin Metab 2012; 1: 179-189.
-
(2012)
J Clin Endocrin Metab
, vol.1
, pp. 179-189
-
-
Hyde, Z.1
Norman, P.2
Flicker, L.3
-
18
-
-
78349305091
-
Serum testosterone and increased mortality in men with coronary heart disease
-
Malkin CJ, Pugh PJ, Morris PD, et al. Serum testosterone and increased mortality in men with coronary heart disease. Heart 2010; 96: 1821-1825.
-
(2010)
Heart
, vol.96
, pp. 1821-1825
-
-
Malkin, C.J.1
Pugh, P.J.2
Morris, P.D.3
-
19
-
-
0036357643
-
Endogenous sex hormones and the development of type 2 diabetes in older men and women; The Rancho Bernardo study
-
Rancho Bernardo Study.
-
OhJ Y, Barrett-Connor E, Wedick NM, Wingard DL, Rancho Bernardo Study. Endogenous sex hormones and the development of type 2 diabetes in older men and women; the Rancho Bernardo study. Diabetes Care 2002; 25: 55-60.
-
(2002)
Diabetes Care
, vol.25
, pp. 55-60
-
-
Ohj, Y.1
Barrett-Connor, E.2
Wedick, N.M.3
Wingard, D.L.4
-
20
-
-
0034106347
-
Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: Prospective results from the Massachusetts male aging study
-
Stellato RK, Feldman HA, Hamdy O, Horton ES, McKinlay JB,. Testosterone, sex hormone-binding globulin, and the development of type 2 diabetes in middle-aged men: prospective results from the Massachusetts male aging study. Diabetes Care 2000; 23: 490-4.
-
(2000)
Diabetes Care
, vol.23
, pp. 490-494
-
-
Stellato, R.K.1
Feldman, H.A.2
Hamdy, O.3
Horton, E.S.4
McKinlay, J.B.5
-
21
-
-
70249149328
-
Impact of androgen deprivation therapy on cardiovascular disease and diabetes
-
Alibhai SM, Duong-Hua M, Sutradhar R, et al. Impact of androgen deprivation therapy on cardiovascular disease and diabetes. J Clin Oncol 2006; 27: 3452-3458.
-
(2006)
J Clin Oncol
, vol.27
, pp. 3452-3458
-
-
Alibhai, S.M.1
Duong-Hua, M.2
Sutradhar, R.3
-
22
-
-
33749058933
-
Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer
-
Keating NL, O'Malley AJ, Smith MR,. Diabetes and cardiovascular disease during androgen deprivation therapy for prostate cancer. J Clin Oncol 2006; 24: 4448-4446.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4448-4446
-
-
Keating, N.L.1
O'Malley, A.J.2
Smith, M.R.3
-
23
-
-
85047052772
-
-
accessed 7/6/13
-
Quality Outcome Framework in Diabetes 2012 /13. http://www.nhsemployers. org/Aboutus/Publications/Documents/ (accessed 7/6/13)
-
(2012)
Quality Outcome Framework in Diabetes
-
-
-
24
-
-
85007756620
-
Management of type 2 diabetes: Summary of updated NICE guidance
-
on behalf of the Guideline Development Group.
-
Home P, Mant J, Diaz J, Turner C, on behalf of the Guideline Development Group. Management of type 2 diabetes: summary of updated NICE guidance. BMJ 2008; 336: 1306-1308.
-
(2008)
BMJ
, vol.336
, pp. 1306-1308
-
-
Home, P.1
Mant, J.2
Diaz, J.3
Turner, C.4
-
25
-
-
84866948645
-
Evidence based medicine inevitably increases testosterone prescribing
-
Hackett GI, Kirby M, Jackson G, Wylie K,. Evidence based medicine inevitably increases testosterone prescribing. BMJ 2012; 345: e6167.
-
(2012)
BMJ
, vol.345
-
-
Hackett, G.I.1
Kirby, M.2
Jackson, G.3
Wylie, K.4
-
26
-
-
84878704250
-
Testosterone replacement therapy with long acting testosterone undecanoate improves sexual function and quality of life parameters vs placebo in a population of men with type 2 diabetes
-
Hackett GI, Cole N, Bhartia M, Kennedy D, Raju J, Wilkinson P,. Testosterone replacement therapy with long acting testosterone undecanoate improves sexual function and quality of life parameters vs placebo in a population of men with type 2 diabetes. J Sex Med 2013; 10: 1612-1627.
-
(2013)
J Sex Med
, vol.10
, pp. 1612-1627
-
-
Hackett, G.I.1
Cole, N.2
Bhartia, M.3
Kennedy, D.4
Raju, J.5
Wilkinson, P.6
-
27
-
-
8744284557
-
Intramuscular testosterone undecanoate: Pharmacokinetic aspects of a novel testosterone formulation during long term treatment for men with hypogonadism
-
Schubert M, Minnemann T, Hübler D, et al. Intramuscular testosterone undecanoate: pharmacokinetic aspects of a novel testosterone formulation during long term treatment for men with hypogonadism. J Clin Endocrinol Metab 2004; 89: 5429-5434.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5429-5434
-
-
Schubert, M.1
Minnemann, T.2
Hübler, D.3
-
28
-
-
0032875463
-
A new Aging Male Symptom rating scale (AMS)
-
Heineman LA, Zimmermann T, Vermeulen A, Theil C,. A new Aging Male Symptom rating scale (AMS). Aging Male 1999; 2: 105-114.
-
(1999)
Aging Male
, vol.2
, pp. 105-114
-
-
Heineman, L.A.1
Zimmermann, T.2
Vermeulen, A.3
Theil, C.4
-
29
-
-
0020527558
-
The Hospital Anxiety and Depression Scale
-
Zigmond AS, Snaith RP,. The Hospital Anxiety and Depression Scale. Acta Psychiatr Scand 1983; 67: 361-70.
-
(1983)
Acta Psychiatr Scand
, vol.67
, pp. 361-370
-
-
Zigmond, A.S.1
Snaith, R.P.2
-
30
-
-
0030926566
-
The International index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction
-
Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A,. The International index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology 1997; 49: 822-30.
-
(1997)
Urology
, vol.49
, pp. 822-830
-
-
Rosen, R.C.1
Riley, A.2
Wagner, G.3
Osterloh, I.H.4
Kirkpatrick, J.5
Mishra, A.6
-
31
-
-
0036633043
-
HOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects
-
Bondara E, Formenttini G, Calcaterra F, et al. HOMA-estimated insulin resistance is an independent predictor of cardiovascular disease in type 2 diabetic subjects. Diabetes Care 2002; 25: 1135-1141.
-
(2002)
Diabetes Care
, vol.25
, pp. 1135-1141
-
-
Bondara, E.1
Formenttini, G.2
Calcaterra, F.3
-
32
-
-
84861331756
-
Comparison of serum testosterone and oestradiol measurements in 3174 European men using platform immunoassay and mass spectrometry; Relevance for the diagnostics in aging men
-
Huhtaniemi I, Tajar A, Lee D, et al. Comparison of serum testosterone and oestradiol measurements in 3174 European men using platform immunoassay and mass spectrometry; relevance for the diagnostics in aging men. Eur J Endocrinol 2012; 166: 983-991.
-
(2012)
Eur J Endocrinol
, vol.166
, pp. 983-991
-
-
Huhtaniemi, I.1
Tajar, A.2
Lee, D.3
-
33
-
-
0033305020
-
A critical evaluation of simple methods for the estimation of free testosterone in serum
-
Vermeulen A, Verdonck L, Kaufman JM,. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999; 84: 3666-3672.
-
(1999)
J Clin Endocrinol Metab
, vol.84
, pp. 3666-3672
-
-
Vermeulen, A.1
Verdonck, L.2
Kaufman, J.M.3
-
34
-
-
78449294931
-
Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: The double-blinded placebo-controlled Moscow study
-
Kalinchenko S, Tishova Y, Mskhalaya G, Gooren L, Giltay E, Saad F,. Effects of testosterone supplementation on markers of the metabolic syndrome and inflammation in hypogonadal men with the metabolic syndrome: the double-blinded placebo-controlled Moscow study. Clin Endocrinol 2010; 73: 602-612.
-
(2010)
Clin Endocrinol
, vol.73
, pp. 602-612
-
-
Kalinchenko, S.1
Tishova, Y.2
Mskhalaya, G.3
Gooren, L.4
Giltay, E.5
Saad, F.6
-
35
-
-
77955145856
-
Effects of testosterone supplementation on depressive symptoms and sexual dysfunction in hypogonadal men with the metabolic syndrome
-
Giltay EJ, Tishova YA, Mskhalaya GJ, et al. Effects of testosterone supplementation on depressive symptoms and sexual dysfunction in hypogonadal men with the metabolic syndrome. J Sex Med 2010; 7: 2572-82.
-
(2010)
J Sex Med
, vol.7
, pp. 2572-2582
-
-
Giltay, E.J.1
Tishova, Y.A.2
Mskhalaya, G.J.3
-
36
-
-
84873060080
-
IPASS: A study on the tolerability and effectiveness of injectable testosterone undecanoate for the treatment of male hypogonadism in a worldwide sample of 1,438 men
-
Zitzmann M, Mattern A, Hanisch J, Looren L, Jones TH, Maggi M,. IPASS: a study on the tolerability and effectiveness of injectable testosterone undecanoate for the treatment of male hypogonadism in a worldwide sample of 1,438 men. J Sex Med 2012; 10: 579-588.
-
(2012)
J Sex Med
, vol.10
, pp. 579-588
-
-
Zitzmann, M.1
Mattern, A.2
Hanisch, J.3
Looren, L.4
Jones, T.H.5
Maggi, M.6
-
37
-
-
33745253926
-
Testosterone undecanoate restores erectile function in a subset of patients with venous leakage: A series of case reports
-
Yassin AA, Saad F, Traish A,. Testosterone undecanoate restores erectile function in a subset of patients with venous leakage: a series of case reports. J Sex Med 2006; 3: 727-735.
-
(2006)
J Sex Med
, vol.3
, pp. 727-735
-
-
Yassin, A.A.1
Saad, F.2
Traish, A.3
-
38
-
-
80054827093
-
Onset of effects of testosterone replacement and time span until maximal effect is achieved
-
Saad F, Aversa A, Isidori A, et al. Onset of effects of testosterone replacement and time span until maximal effect is achieved. Eur J Endocrinol 2011; 165: 675-685.
-
(2011)
Eur J Endocrinol
, vol.165
, pp. 675-685
-
-
Saad, F.1
Aversa, A.2
Isidori, A.3
-
39
-
-
78650788563
-
Hypogonadal men nonresponders to the PDE5 inhibitor tadalafil benefit from normalization of testosterone levels with a 1% hydroalcoholic testosterone gel in the treatment of erectile dysfunction (TADTEST study)
-
Buvat J, Montorsi F, Maggi M, et al. Hypogonadal men nonresponders to the PDE5 inhibitor tadalafil benefit from normalization of testosterone levels with a 1% hydroalcoholic testosterone gel in the treatment of erectile dysfunction (TADTEST study). J Sex Med 2011; 8: 284-93.
-
(2011)
J Sex Med
, vol.8
, pp. 284-293
-
-
Buvat, J.1
Montorsi, F.2
Maggi, M.3
-
40
-
-
39749105966
-
Effects of tadalafil once daily in men with diabetes and erectile dysfunction
-
Hatzichristou D, Gambia M, Rubio-Aurioles E, Buvat J, brock G, Spera G,. Effects of tadalafil once daily in men with diabetes and erectile dysfunction. Diabet Med 2008; 25: 138-146.
-
(2008)
Diabet Med
, vol.25
, pp. 138-146
-
-
Hatzichristou, D.1
Gambia, M.2
Rubio-Aurioles, E.3
Buvat, J.4
Brock, G.5
Spera, G.6
-
41
-
-
84872546745
-
Effect of testosterone replacement on response to sildenafil citrate in men with erectile dysfunction
-
Spitzer M, Basaria S, Travison TG, et al. Effect of testosterone replacement on response to sildenafil citrate in men with erectile dysfunction. Annals Intern Med 2012; 157: 681-691.
-
(2012)
Annals Intern Med
, vol.157
, pp. 681-691
-
-
Spitzer, M.1
Basaria, S.2
Travison, T.G.3
-
42
-
-
84885585545
-
The effect of testosterone replacement on mood and well being in men with erectile dysfunction
-
Spitzer M, Basaria S, Travison TG, Davda MN, DeRogatis L, Bhasin S,. The effect of testosterone replacement on mood and well being in men with erectile dysfunction. Andrology 2013; 1: 475-482.
-
(2013)
Andrology
, vol.1
, pp. 475-482
-
-
Spitzer, M.1
Basaria, S.2
Travison, T.G.3
Davda, M.N.4
Derogatis, L.5
Bhasin, S.6
-
43
-
-
33745684473
-
Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolemia in hypogonadal men with type 2 diabetes
-
Kapoor D, Goodwin E, Channer KS, Jones TH,. Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolemia in hypogonadal men with type 2 diabetes. Eur J Endocrinol 2006; 154: 899-906.
-
(2006)
Eur J Endocrinol
, vol.154
, pp. 899-906
-
-
Kapoor, D.1
Goodwin, E.2
Channer, K.S.3
Jones, T.H.4
-
44
-
-
79956271879
-
A placebo controlled study on the effects of transdermal testosterone gel in hypogonadal men with type ii diabetes or metabolic syndrome in diabetic control and insulin sensitivity: The TIMES 2 study
-
Jones TH, Arver S, Behre H, et al. A placebo controlled study on the effects of transdermal testosterone gel in hypogonadal men with type ii diabetes or metabolic syndrome in diabetic control and insulin sensitivity: the TIMES 2 study. Diabetes Care 2011; 34: 828-837.
-
(2011)
Diabetes Care
, vol.34
, pp. 828-837
-
-
Jones, T.H.1
Arver, S.2
Behre, H.3
-
45
-
-
69949178483
-
Fifty-two-week treatment with diet and exercise plus transdermal testosterone reverses the metabolic syndrome and improves glycemic control in men with newly diagnosed type 2 diabetes and subnormal plasma testosterone
-
Heufelder AE, Saad F, Bunck MC, Gooren L,. Fifty-two-week treatment with diet and exercise plus transdermal testosterone reverses the metabolic syndrome and improves glycemic control in men with newly diagnosed type 2 diabetes and subnormal plasma testosterone. J Androl 2009; 30: 726-733.
-
(2009)
J Androl
, vol.30
, pp. 726-733
-
-
Heufelder, A.E.1
Saad, F.2
Bunck, M.C.3
Gooren, L.4
-
46
-
-
29144469309
-
Adverse events associated with testosterone replacement in middle aged and older men: A meta-analysis of randomised placebo controlled trials
-
Calof OM, Singh AB, Lee ML, et al. Adverse events associated with testosterone replacement in middle aged and older men: a meta-analysis of randomised placebo controlled trials. J Gerontol 2005; 60: 1451-7.
-
(2005)
J Gerontol
, vol.60
, pp. 1451-1457
-
-
Calof, O.M.1
Singh, A.B.2
Lee, M.L.3
-
47
-
-
58149512149
-
Testosterone therapy in hypogonadal men and prostate cancer risk: A systemic review
-
Shabsigh R, Crawford ED, Nehra A, Slawin KM,. Testosterone therapy in hypogonadal men and prostate cancer risk: a systemic review. Int J Impot Res 2009; 21: 9-23.
-
(2009)
Int J Impot Res
, vol.21
, pp. 9-23
-
-
Shabsigh, R.1
Crawford, E.D.2
Nehra, A.3
Slawin, K.M.4
|