Antimalarial efficacy of hydroxyethylapoquinine (SN-119) and its derivatives

Antimicrobial Agents and Chemotherapy

Volumn 58, Issue 2, 2014, Pages 820-827

  Sanders, Natalie G ^a   Meyers, David J ^b   Sullivan, David J ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTESUNATE; HEME; HYDROXYETHYLAPOQUINIDINE; HYDROXYETHYLAPOQUININE; HYDROXYETHYLQUINIDINE; HYDROXYETHYLQUININE; POTASSIUM CHANNEL HERG; QUINIDINE; QUINIDINE DERIVATIVE; QUININE; QUININE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; BODY WEIGHT; CHO CELL; CONTROLLED STUDY; CRYSTALLIZATION; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IC 50; MALARIA; MOUSE; NONHUMAN; PARASITEMIA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEREOISOMERISM; SURVIVAL;

ANIMALS; ANTIMALARIALS; CHO CELLS; CRICETULUS; DRUG RESISTANCE; ERYTHROCYTES; ETHER-A-GO-GO POTASSIUM CHANNELS; GENE EXPRESSION; HUMANS; INHIBITORY CONCENTRATION 50; MALARIA; MICE; MICE, INBRED C57BL; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; QUINIDINE; QUININE; SURVIVAL ANALYSIS;

EID: 84893502367     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01704-13     Document Type: Article

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