-
1
-
-
33751091519
-
The H-linked monocarboxylate transporter (MCT1/SLC16A1): A potential therapeutic target for high-risk neuroblast-oma
-
Fang J, Quinones QJ, Holman TL, Morowitz MJ, Wang Q, Zhao H, et al. The H-linked monocarboxylate transporter (MCT1/SLC16A1): A potential therapeutic target for high-risk neuroblast-oma. Mol Pharmacol 2006;70:2108-15.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 2108-2115
-
-
Fang, J.1
Quinones, Q.J.2
Holman, T.L.3
Morowitz, M.J.4
Wang, Q.5
Zhao, H.6
-
2
-
-
0020519825
-
Action of the antitumor and antisperma-togenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria
-
Floridi A, Lehninger AL. Action of the antitumor and antisperma-togenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria. Arch Biochem Biophys 1983;226:73-83.
-
(1983)
Arch Biochem Biophys
, vol.226
, pp. 73-83
-
-
Floridi, A.1
Lehninger, A.L.2
-
3
-
-
84871706468
-
1H MRS of DB-1 melanoma xenografts: Lonidamine selectively decreases tumor intracellular pH and energy status and sensitizes tumors to melphalan
-
1H MRS of DB-1 melanoma xenografts: lonidamine selectively decreases tumor intracellular pH and energy status and sensitizes tumors to melphalan. NMR Biomed 2012;26:98-105.
-
(2012)
NMR Biomed
, vol.26
, pp. 98-105
-
-
Nath, K.1
Nelson, D.S.2
Ho, A.M.3
Lee, S.-C.4
Darpolor, M.M.5
Pickup, S.6
-
4
-
-
0021237882
-
Lonidamine: A hyperthermic sensitizer of HeLa cells in culture and of the Meth-A tumor in vivo
-
Kim JH, Kim SH, Alfieri A, Young CW, Silvestrini B. Lonidamine: A hyperthermic sensitizer of HeLa cells in culture and of the Meth-A tumor in vivo. Oncology 1984;41:30-5.
-
(1984)
Oncology
, vol.41
, pp. 30-35
-
-
Kim, J.H.1
Kim, S.H.2
Alfieri, A.3
Young, C.W.4
Silvestrini, B.5
-
5
-
-
0023858514
-
Lonidamine-induced, pH dependent inhibition of cellular oxygen utilization
-
Stryker JA, Gerweck LE. Lonidamine-induced, pH dependent inhibition of cellular oxygen utilization. Radiat Res 1988;113: 356-61.
-
(1988)
Radiat Res
, vol.113
, pp. 356-361
-
-
Stryker, J.A.1
Gerweck, L.E.2
-
6
-
-
0025815783
-
Enhancement of sensitivity to hyperthermia by lonidamine in human cancer cells
-
Raaphorst GP, Feeley MM, Martin L, Danjoux CE, Maroun J, Desanctis AJ, et al. Enhancement of sensitivity to hyperthermia by lonidamine in human cancer cells. Int J Hyperthermia 1991;7: 763-72.
-
(1991)
Int J Hyperthermia
, vol.7
, pp. 763-772
-
-
Raaphorst, G.P.1
Feeley, M.M.2
Martin, L.3
Danjoux, C.E.4
Maroun, J.5
Desanctis, A.J.6
-
7
-
-
0031883221
-
Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification
-
Ben-Yoseph O, Lyons JC, Song CW, Ross BD. Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification. J Neurooncol 1998;36:149-57.
-
(1998)
J Neurooncol
, vol.36
, pp. 149-157
-
-
Ben-Yoseph, O.1
Lyons, J.C.2
Song, C.W.3
Ross, B.D.4
-
8
-
-
0020682326
-
Effects of lonidamine alone or combined with hyperthermia in some experimental cell and tumour systems
-
Silvestrini B, Hahn GM, Cioli V, De Martino C. Effects of lonidamine alone or combined with hyperthermia in some experimental cell and tumour systems. Br J Cancer 1983;47:221-31.
-
(1983)
Br J Cancer
, vol.47
, pp. 221-231
-
-
Silvestrini, B.1
Hahn, G.M.2
Cioli, V.3
De Martino, C.4
-
9
-
-
0021234309
-
Lonidamine, a new approach to cancer therapy
-
Caputo A, Silvestrini B. Lonidamine, a new approach to cancer therapy. Oncology 1984;41:2-6.
-
(1984)
Oncology
, vol.41
, pp. 2-6
-
-
Caputo, A.1
Silvestrini, B.2
-
10
-
-
0025776309
-
Reversal of adriamycin resistance by lonidamine in a human breast cancer cell line
-
Citro G, Cucco C, Verdina A, Zupi G. Reversal of adriamycin resistance by lonidamine in a human breast cancer cell line. Br J Cancer 1991;64:534-6.
-
(1991)
Br J Cancer
, vol.64
, pp. 534-536
-
-
Citro, G.1
Cucco, C.2
Verdina, A.3
Zupi, G.4
-
11
-
-
0026084854
-
Lonidamine as a modulator of alkylating agent activity in vitro and in vivo
-
Teicher BA, Herman TS, Holden SA, Epelbaum R, Liu S, Frei III E. Lonidamine as a modulator of alkylating agent activity in vitro and in vivo. Cancer Res 1991;51:780-4.
-
(1991)
Cancer Res
, vol.51
, pp. 780-784
-
-
Teicher, B.A.1
Herman, T.S.2
Holden, S.A.3
Epelbaum, R.4
Liu, S.5
Frei III, E.6
-
12
-
-
0037368877
-
Lonidamine: Efficacy and safety in clinical trials for the treatment of solid tumors
-
Di Cosimo S, Ferretti G, Papaldo P, Carlini P, Fabi A, Cognetti F. Lonidamine: Efficacy and safety in clinical trials for the treatment of solid tumors. Drugs Today (Barc) 2003;39:157-74.
-
(2003)
Drugs Today (Barc)
, vol.39
, pp. 157-174
-
-
Di Cosimo, S.1
Ferretti, G.2
Papaldo, P.3
Carlini, P.4
Fabi, A.5
Cognetti, F.6
-
13
-
-
0017346116
-
Modification of cell lethality at elevated temperatures. The pH effect
-
Gerweck LE. Modification of cell lethality at elevated temperatures. The pH effect. Radiat Res 1977;70:224-35.
-
(1977)
Radiat Res
, vol.70
, pp. 224-235
-
-
Gerweck, L.E.1
-
14
-
-
0018853951
-
The effect of pH on cell lethality induced by hyperthermic treatment
-
Freeman ML, Raaphorst GP, Hopwood LE, Dewey WC. The effect of pH on cell lethality induced by hyperthermic treatment. Cancer 1980;45:2291-300.
-
(1980)
Cancer
, vol.45
, pp. 2291-2300
-
-
Freeman, M.L.1
Raaphorst, G.P.2
Hopwood, L.E.3
Dewey, W.C.4
-
15
-
-
0018934148
-
Tumor cell sensitivity to hyperthermia as a function of extracellular and intracellular pH
-
Hofer KG, Mivechi NF. Tumor cell sensitivity to hyperthermia as a function of extracellular and intracellular pH. J Natl Cancer Inst 1980;65:621-5.
-
(1980)
J Natl Cancer Inst
, vol.65
, pp. 621-625
-
-
Hofer, K.G.1
Mivechi, N.F.2
-
16
-
-
0023947709
-
The role of low intracellular or extracellular pH in sensitization to hyperthermia
-
Chu G, Dewey WC. The role of low intracellular or extracellular pH in sensitization to hyperthermia. Radiat Res 1988;114:154-67.
-
(1988)
Radiat Res
, vol.114
, pp. 154-167
-
-
Chu, G.1
Dewey, W.C.2
-
17
-
-
0025327518
-
The role of intracellular pH and its variance in low pH sensitization of killing by hyperthermia
-
Chu GL, WangZ, Hyun WC, Pershadsingh HA, Fulwyler MJ, Dewey WC. The role of intracellular pH and its variance in low pH sensitization of killing by hyperthermia. Radiat Res 1990;122: 288-93.
-
(1990)
Radiat Res
, vol.122
, pp. 288-293
-
-
Chu, G.L.1
Wangz Hyun, W.C.2
Pershadsingh, H.A.3
Fulwyler, M.J.4
Dewey, W.C.5
-
18
-
-
0026601987
-
Modification of intracellular pH and thermosensitivity
-
Lyons JC, Kim GE, Song CW. Modification of intracellular pH and thermosensitivity. Radiat Res 1992;129:79-87.
-
(1992)
Radiat Res
, vol.129
, pp. 79-87
-
-
Lyons, J.C.1
Kim, G.E.2
Song, C.W.3
-
19
-
-
0842325193
-
Acute extracellular acidification reduces intracellular pH, 42°C-induction of heat shock proteins and clonal survival of human melanoma cells grown at pH 6.7
-
Coss RA, Storck CW, Wachsberger PR, Reilly J, Leeper DB, Berd D, et al. Acute extracellular acidification reduces intracellular pH, 42°C-induction of heat shock proteins and clonal survival of human melanoma cells grown at pH 6.7. Int J Hyperthermia 2004; 20:93-106.
-
(2004)
Int J Hyperthermia
, vol.20
, pp. 93-106
-
-
Coss, R.A.1
Storck, C.W.2
Wachsberger, P.R.3
Reilly, J.4
Leeper, D.B.5
Berd, D.6
-
20
-
-
0842273229
-
Intracellular acidification abrogates the heat shock response and compromises survival of human melanoma cells
-
Coss, RA, Storck CW, Daskalakis C, Berd D, Wahl ML. Intracellular acidification abrogates the heat shock response and compromises survival of human melanoma cells. Mol Cancer Ther 2003;2:383-8.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 383-388
-
-
Coss, R.A.1
Storck, C.W.2
Daskalakis, C.3
Berd, D.4
Wahl, M.L.5
-
21
-
-
0027316026
-
Potentiation of DNA-adduct formation and cytotoxicity of platinum-containing drugs by low pH
-
Atema A, Buurman KJ, Noteboom E, Smets LA. Potentiation of DNA-adduct formation and cytotoxicity of platinum-containing drugs by low pH. Int J Cancer 1993;54:166-72.
-
(1993)
Int J Cancer
, vol.54
, pp. 166-172
-
-
Atema, A.1
Buurman, K.J.2
Noteboom, E.3
Smets, L.A.4
-
22
-
-
0024348433
-
Hydrogen ion-mediated enhancement of cytotoxicity of bis-chloroethylating drugs in rat mammary carcinoma cells in vitro
-
Jahde E, Glusenkamp KH, Klunder I, Hulser DF, Tietze LF, Rajewsky MF. Hydrogen ion-mediated enhancement of cytotoxicity of bis-chloroethylating drugs in rat mammary carcinoma cells in vitro. Cancer Res 1989;49:2965-72.
-
(1989)
Cancer Res
, vol.49
, pp. 2965-2972
-
-
Jahde, E.1
Glusenkamp, K.H.2
Klunder, I.3
Hulser, D.F.4
Tietze, L.F.5
Rajewsky, M.F.6
-
24
-
-
0027538671
-
Metabolic response of AH13r rat tumours to cyclophosphamide as monitored by pO2 and pH semi-microelec-trodes
-
Jahde E, Roszinski S, Volk T, Glusenkamp KH, Wiedemann G, Rajewsky MF. Metabolic response of AH13r rat tumours to cyclophosphamide as monitored by pO2 and pH semi-microelec-trodes. Eur J Cancer 1992;29:116-22.
-
(1992)
Eur J Cancer
, vol.29
, pp. 116-122
-
-
Jahde, E.1
Roszinski, S.2
Volk, T.3
Glusenkamp, K.H.4
Wiedemann, G.5
Rajewsky, M.F.6
-
25
-
-
33745110220
-
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
-
Gerweck LE, Vijayappa S, Kozin S. Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics. Mol Cancer Ther 2006;5:1275-9.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1275-1279
-
-
Gerweck, L.E.1
Vijayappa, S.2
Kozin, S.3
-
26
-
-
0036594889
-
Regulation of intracellular pH in human melanoma: Potential therapeutic implications
-
Wahl ML, Owen JA, Burd R, Herlands RA, Nogami SS, Rodeck U, et al. Regulation of intracellular pH in human melanoma: potential therapeutic implications. Mol Cancer Ther 2002;1:617-28.
-
(2002)
Mol Cancer Ther
, vol.1
, pp. 617-628
-
-
Wahl, M.L.1
Owen, J.A.2
Burd, R.3
Herlands, R.A.4
Nogami, S.S.5
Rodeck, U.6
-
27
-
-
0026425675
-
Growth and metastasis of fresh human melanoma tissue in mice with severe combined immunodeficiency
-
Hill LL, Korngold R, Jaworsky C, Murphy G, McCue P, Berd D. Growth and metastasis of fresh human melanoma tissue in mice with severe combined immunodeficiency. Cancer Res 1991;51: 4937-41.
-
(1991)
Cancer Res
, vol.51
, pp. 4937-4941
-
-
Hill, L.L.1
Korngold, R.2
Jaworsky, C.3
Murphy, G.4
McCue, P.5
Berd, D.6
-
28
-
-
0001340102
-
Accurate whole spectrum measurements of intracellular pH and [Na+]
-
Owen CS, Wahl ML, Leeper DB, Perry HD, Bobyock SB, Russel M, et al. Accurate whole spectrum measurements of intracellular pH and [Na+]. J Fluorescence 1995;5:329-35.
-
(1995)
J Fluorescence
, vol.5
, pp. 329-335
-
-
Owen, C.S.1
Wahl, M.L.2
Leeper, D.B.3
Perry, H.D.4
Bobyock, S.B.5
Russel, M.6
-
29
-
-
0030034395
-
Thermotolerance and intracellular pH in two Chinese hamster cell lines adapted to growth at low pH
-
Wahl ML, Coss RA, Bobyock SB, Leeper DB, Owen CS. Thermotolerance and intracellular pH in two Chinese hamster cell lines adapted to growth at low pH. J Cell Physiol 1996;166: 438-45.
-
(1996)
J Cell Physiol
, vol.166
, pp. 438-445
-
-
Wahl, M.L.1
Coss, R.A.2
Bobyock, S.B.3
Leeper, D.B.4
Owen, C.S.5
-
30
-
-
0030771009
-
Altered proton extrusion in cells adapted to growth at low extracellular pH
-
Owen CS, Pooler PM, Wahl ML, Coss RA, Leeper DB. Altered proton extrusion in cells adapted to growth at low extracellular pH. J Cell Physiol 1997;167:397-405.
-
(1997)
J Cell Physiol
, vol.167
, pp. 397-405
-
-
Owen, C.S.1
Pooler, P.M.2
Wahl, M.L.3
Coss, R.A.4
Leeper, D.B.5
-
31
-
-
0034053775
-
Intracellular pH regulation in a nonmalignant and a derived malignant human breast cell line
-
Wahl ML, Pooler PM, Briand P, Leeper DB, Owen CS. Intracellular pH regulation in a nonmalignant and a derived malignant human breast cell line. J Cell Physiol 2000;18:373-89.
-
(2000)
J Cell Physiol
, vol.18
, pp. 373-389
-
-
Wahl, M.L.1
Pooler, P.M.2
Briand, P.3
Leeper, D.B.4
Owen, C.S.5
-
32
-
-
0020067552
-
Modulation of heat-shock polypeptide synthesis in HeLa cells during hyperthermia and recovery
-
Hickey ED, Weber LA. Modulation of heat-shock polypeptide synthesis in HeLa cells during hyperthermia and recovery. Biochemistry 1982;21:1513-21.
-
(1982)
Biochemistry
, vol.21
, pp. 1513-1521
-
-
Hickey, E.D.1
Weber, L.A.2
-
33
-
-
0036737115
-
Acute extracellular acidification increases nuclear associated protein levels in human melanoma cells during 42 °c hyperthermia and enhances cell killing
-
Han J-S, Storck CW, Wachsberger PR, Leeper DB, Berd D, Wahl ML, et al. Acute extracellular acidification increases nuclear associated protein levels in human melanoma cells during 42 °C hyperthermia and enhances cell killing. Int J Hyperthermia 2002; 18:404-15.
-
(2002)
Int J Hyperthermia
, vol.18
, pp. 404-415
-
-
Han, J.-S.1
Storck, C.W.2
Wachsberger, P.R.3
Leeper, D.B.4
Berd, D.5
Wahl, M.L.6
-
34
-
-
0029073748
-
Mechanism of action of the antineoplastic drug lonidamine: P and C nuclear magnetic resonance studies
-
Ben-Horin H, Tassini M, Vivi A, Navon G, Kaplan O. Mechanism of action of the antineoplastic drug lonidamine: P and C nuclear magnetic resonance studies. Cancer Res 1995;55:2814-21.
-
(1995)
Cancer Res
, vol.55
, pp. 2814-2821
-
-
Ben-Horin, H.1
Tassini, M.2
Vivi, A.3
Navon, G.4
Kaplan, O.5
-
35
-
-
0031048152
-
Comparison of action of the anti-neoplastic drug lonidamine on drug-sensitive and drug-resistant human breast cancer cells: P and C nuclear magnetic resonance studies
-
Vivi A, Tassini M, Ben-Horin H, Navon G, Kaplan O. Comparison of action of the anti-neoplastic drug lonidamine on drug-sensitive and drug-resistant human breast cancer cells: P and C nuclear magnetic resonance studies. Breast Cancer Res Treat 1997;43: 15-25.
-
(1997)
Breast Cancer Res Treat
, vol.43
, pp. 15-25
-
-
Vivi, A.1
Tassini, M.2
Ben-Horin, H.3
Navon, G.4
Kaplan, O.5
-
36
-
-
0034665565
-
Noninvasive real-time monitoring of intracellular cancer cell metabolism and response to lonidamine treatment using diffusion weighted proton magnetic resonance spectroscopy
-
Mardor Y, Kaplan O, Sterin M, Ruiz-Cabello J, Ash E, Roth Y, et al. Noninvasive real-time monitoring of intracellular cancer cell metabolism and response to lonidamine treatment using diffusion weighted proton magnetic resonance spectroscopy. Cancer Res 2000;60:5179-86.
-
(2000)
Cancer Res
, vol.60
, pp. 5179-5186
-
-
Mardor, Y.1
Kaplan, O.2
Sterin, M.3
Ruiz-Cabello, J.4
Ash, E.5
Roth, Y.6
-
37
-
-
29144485524
-
Inhibiting induction of heat shock proteins as a strategy to enhance cancer therapy
-
Coss RA. Inhibiting induction of heat shock proteins as a strategy to enhance cancer therapy. Int J Hyperthermia 2005;21: 695-701.
-
(2005)
Int J Hyperthermia
, vol.21
, pp. 695-701
-
-
Coss, R.A.1
|