Quantification of human plasma-busulfan concentration by liquid chromatography-tandem mass spectrometry

Annals of Laboratory Medicine

Volumn 34, Issue 1, 2014, Pages 7-14

  Moon, Soo Young ^a   Lim, Min Kyoo ^a   Hong, Susie ^a   Jeon, Yongbum ^a   Han, Minje ^a   Song, Sang Hoon ^a   Lim, Kyoung Soo ^a   Yu, Kyung Sang ^a   Jang, In Jin ^a   Lee, Ji Won ^a   Kang, Hyoung Jin ^a   Song, Junghan ^b  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University Bundang Hospital   (South Korea)

Author keywords

Busulfan.; Drug monitoring.; Hematopoietic stem cell transplantation; Liquid chromatography.; Tandem mass spectrometry.

Indexed keywords

BUSULFAN;

ARTICLE; BLOOD; CHILD; DRUG MONITORING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INFANT; LIQUID CHROMATOGRAPHY; PRESCHOOL CHILD; QUALITY CONTROL; STANDARD; TANDEM MASS SPECTROMETRY;

BUSULFAN; DRUG MONITORING; HEMATOPOIETIC STEM CELL TRANSPLANTATION; LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

BUSULFAN; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; QUALITY CONTROL; REFERENCE STANDARDS; TANDEM MASS SPECTROMETRY;

EID: 84893394577     PISSN: 22343806     EISSN: 22343814     Source Type: Journal    
DOI: 10.3343/alm.2014.34.1.7     Document Type: Article

References (31)

1. Nath CE and Shaw PJ. Busulphan in blood and marrow transplantation: dose, route, frequency and role of therapeutic drug monitoring. Curr Clin Pharmacol 2007;2:75-91
2. Ciurea SO and Andersson BS. Busulfan in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2009;15:523-36
3. Russell JA and Kangarloo SB. Therapeutic drug monitoring of busulfan in transplantation. Curr Pharm Des 2008;14:1936-49
4. Dean RM, Pohlman B, Sweetenham JW, Sobecks RM, Kalaycio ME, Smith SD, et al. Superior survival after replacing oral with intravenous busulfan in autologous stem cell transplantation for non-Hodgkin lymphoma with busulfan, cyclophosphamide and etoposide. Br J Haematol 2010;148:226-34
5. Lee JW, Kang HJ, Lee SH, Yu KS, Kim NH, Yuk YJ, et al. Highly variable pharmacokinetics of once-daily intravenous busulfan when combined with fludarabine in pediatric patients: phase I clinical study for determination of optimal once-daily busulfan dose using pharmacokinetic modeling. Biol Blood Marrow Transplant 2012;18:944-50
6. Gaziev J, Nguyen L, Puozzo C, Mozzi AF, Casella M, Perrone Donnorso M, et al. Novel pharmacokinetic behavior of intravenous busulfan in children with thalassemia undergoing hematopoietic stem cell transplantation: a prospective evaluation of pharmacokinetic and pharmacodynamic profile with therapeutic drug monitoring. Blood 2010;115:4597-604
7. Paci A, Vassal G, Moshous D, Dalle JH, Bleyzac N, Neven B, et al. Pharmacokinetic behavior and appraisal of intravenous busulfan dosing in infants and older children: the results of a population pharmacokinetic study from a large pediatric cohort undergoing hematopoietic stem-cell transplantation. Ther Drug Monit 2012;34:198-208
8. Méresse V, Hartmann O, Vassal G, Benhamou E, Valteau-Couanet D, Brugieres L, et al. Risk factors for hepatic veno-occlusive disease after high-dose busulfan-containing regimens followed by autologous bone marrow transplantation: a study in 136 children. Bone Marrow Transplant 1992;10:135-41
9. Carreras E, Rosiñol L, Terol MJ, Alegre A, de Arriba F, García-Laraña J, et al. Veno- occlusive disease of the liver after high-dose cytoreductive therapy with busulfan and melphalan for autologous blood stem cell transplantation in multiple myeloma patients. Biol Blood Marrow Transplant 2007;13:1448-54
10. Chen TL, Grochow LB, Hurowitz LA, Brundrett RB. Determination of busulfan in human plasma by gas chromatography with electron-capture detection. J Chromatogr 1988;425:303
11. Quernin MH, Poonkuzhali B, Montes C, Krishnamoorthy R, Dennison D, Srivastava A, et al. Quantification of busulfan in plasma by gas chromatography-mass spectrometry following derivatization with tetrafluorothiophenol. J Chromatogr B Biomed Sci Appl 1998;709:47-56
12. Bleyzac N, Barou P, Aulagner G. Rapid and sensitive high-performance liquid chromatographic method for busulfan assay in plasma. J Chromatogr B Biomed Sci Appl 2000;742:427-32
13. Peris JE, Latorre JA, Castel V, Verdeguer A, Esteve S, Torres-Molina F. Determination of busulfan in human plasma using high-performance liquid chromatography with pre- column derivatization and fluorescence detection. J Chromatogr B Biomed Sci Appl 1999;730:33-40
14. Courtney JB, Harney R, Li Y, Lundell G, McMillin GA, Agarwal G, et al. Determination of busulfan in human plasma using an ELISA format. Ther Drug Monit 2009;31:489-94
15. Mürdter TE, Coller J, Claviez A, Schönberger F, Hofmann U, Dreger P, et al. Sensitive and rapid quantification of busulfan in small plasma volumes by liquid chromatography-electrospray mass spectrometry. Clin Chem 2001;47:1437-42
16. Quernin MH, Duval M, Litalien C, Vilmer E, Aigrain EJ. Quantification of busulfan in plasma by liquid chromatography-ion spray mass spectrometry. Application to pharmacokinetic studies in children. J Chromatogr B Biomed Sci Appl 2001;763:61-9
17. Kellogg MD, Law T, Sakamoto M, Rifai N. Tandem mass spectrometry method for the quantification of serum busulfan. Ther Drug Monit 2005;27:625-9
18. dos Reis EO, Vianna-Jorge R, Suarez-Kurtz G, Lima EL, Azevedo Dde A. Development of a rapid and specific assay for detection of busulfan in human plasma by high- performance liquid chromatography/electrospray ionization tandem mass spectrometry. Rapid Commun Mass Spectrom 2005;19:1666-74
19. Bunch DR, Heideloff C, Ritchie JC, Wang S. A fast and simple assay for busulfan in serum or plasma by liquid chromatography-tandem mass spectrometry using turbulent flow online extraction technology. J Chromatogr B Analyt Technol Biomed Life Sci 2010;878:3255-8
20. Ansari M, Uppugunduri CR, Déglon J, Théorêt Y, Versace F, Gumy-Pause F, et al. A simplified method for busulfan monitoring using dried
21. Food and Drug Administration. Guidance for Industry: Bioanalytical method validation. Rockville, MD: U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, 2001
22. Clinical and Laboraotry Standards Institute. User verification of performance for precision and trueness; Approved guideline. 2nd ed. EP15-A2. Wayne, PA: Clinical and Laboraotry Standards Institute, 2005
23. Matuszewski BK, Constanzer ML, Chavez-Eng CM. Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS. Anal Chem 2003;75:3019-30
24. NCCLS. Evaluation of the linearity of quantitative measurement procedures: a statistical approach; approved guideline. NCCLS document EP6-A. Wayne, PA: National Committee for Clinical Laboratory Standards, 2003
25. International Conference on Harmonization. Q2B: validation of analytical procedures: methodology. US FDA Federal Register 1997;62:27463-7.
26. Lee HJ, Kim SY, Lee SM, Heo J, Kim HH, Chang CL, et al. Elecsys hepatitis B surface antigen quantitative assay: performance evaluation and correlation with hepatitis B virus DNA during 96 weeks of follow-up in chronic hepatitis B patients. Ann Lab Med 2012;32:420-5
27. Snyder ML and Ritchie JC. Quantification of busulfan in plasma using liquid chromatography electrospray tandem mass spectrometry (HPLC-ESI-MS/MS). Methods Mol Biol 2010;603:129-36
28. Oechtering D, Boos J, Hempel G. Monitoring of N,N-dimethylacetamide in children during i.v.-busulfan therapy by liquid chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2006;838:129-34
29. Hempel G, Oechtering D, Lanvers-Kaminsky C, Klingebiel T, Vormoor J, Gruhn B, et al. Cytotoxicity of dimethylacetamide and pharmacokinetics in children receiving intravenous busulfan. J Clin Oncol 2007;25:1772-8
30. Cooper AJ, Younis IR, Niatsetskaya ZV, Krasnikov BF, Pinto JT, Petros WP, et al. Metabolism of the cysteine S-conjugate of busulfan involves a beta-lyase reaction. Drug Metab Dispos 2008;36:1546-52
31. Versace F, Uppugunduri CR, Krajinovic M, Théorêt Y, Gumy-Pause F, Mangin P, et al. A novel method for quantification of sulfolane (a metabolite of busulfan) in plasma by gas chromatography-tandem mass spectrometry. Anal Bioanal Chem 2012;404:1831-8