Cholesteryl ester transfer proteins from different species do not have equivalent activities

Journal of Lipid Research

Volumn 55, Issue 2, 2014, Pages 258-265

  Morton, Richard E ^a   Izem, Lahoucine ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

High density lipoprotein; Thimerosal inhibition; TP2 antibody; Triglyceride; Unidirectional lipid transfer; Very low density lipoprotein

Indexed keywords

HIGH DENSITY LIPOPROTEIN; THIMEROSAL INHIBITION; TP2 ANTIBODY; TRIGLYCERIDE; UNIDIRECTIONAL LIPID TRANSFER; VERY LOW DENSITY LIPOPROTEIN;

ANIMALS; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL ESTERS; CRICETINAE; HAPLORHINI; HEK293 CELLS; HUMANS; LIPOPROTEINS; RABBITS; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; TRIGLYCERIDES;

EID: 84893373421     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M043646     Document Type: Article

References (35)

1. Nichols, A. V., and L. Smith.1965.Effect of very low-density lipoproteins on lipid transfer in incubated serum. J. Lipid Res. 6 : 206-210.
2. Zilversmit, D. B., L. B. Hughes, and J. Balmer.1975.Stimulation of cholesterol ester exchange by lipoprotein-free rabbit plasma. Biochim. Biophys. Acta.409 : 393-398.
3. Morton, R. E., and D. B. Zilversmit.1982.Purification and characterization of lipid transfer protein(s) from human lipoproteindeficient plasma. J. Lipid Res. 23 : 1058-1067.
4. Hesler, C. B., A. R. Tall, T. L. Swenson, P. K. Weech, Y. L. Marcel, and R. W. Milne.1988.Monoclonal antibodies to the Mr 74,000 cholesteryl ester transfer protein neutralize all of the cholesteryl ester and triglyceride transfer activities in human plasma. J. Biol. Chem. 263 : 5020-5023.
5. Wang, S., L. Deng, M. L. Brown, L. B. Agellon, and A. R. Tall.1991.Structure-function studies of human cholesteryl ester transfer protein by linker insertion scanning mutagenesis. Biochemistry.30 : 3484-3490.
6. Qiu, X., A. Mistry, M. Ammirati, B. Chrunyk, R. Clark, Y. Cong, J. Culp, D. Danley, T. Freeman, K. Geoghegan, et al.2007.Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules. Nat. Struct. Mol. Biol. 14 : 106-113.
7. Zhang, Z., S. Yamashita, K. Hirano, Y. Nakagawa-Toyama, A. Matsuyama, M. Nishida, N. Sakai, M. Fukasawa, H. Arai, J. Miyagawa, et al.2001.Expression of cholesteryl ester transfer protein in human atherosclerotic lesions and its implication in reverse cholesterol transport. Atherosclerosis.159 : 67-75.
8. Izem, L., and R. E. Morton.2001.Cholesteryl ester transfer protein biosynthesis and cellular cholesterol homeostasis are tightly interconnected. J. Biol. Chem. 276 : 26534-26541.
9. Huang, Z., A. Inazu, M. A. Kawashiri, A. Nohara, T. Higashikata, and H. Mabuchi.2003.Dual effects on HDL metabolism by cholesteryl ester transfer protein inhibition in HepG2 cells. Am. J. Physiol. Endocrinol. Metab. 284 : E1210-E1219.
10. Izem, L., and R. E. Morton.2007.Possible role for intracellular cholesteryl ester transfer protein in adipocyte lipid metabolism and storage. J. Biol. Chem. 282 : 21856-21865.
11. Brunner, J., P. Skrabal, and H. Hauser.1976.Single bilayer vesicles prepared without sonication. Physico-chemical properties. Biochim. Biophys. Acta.455 : 322-331.
12. Havel, R. J., H. A. Eder, and J. H. Bragdon.1955.The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34 : 1345-1353.
13. Morton, R. E., and D. B. Zilversmit.1981.A plasma inhibitor of triglyceride and cholesteryl ester transfer activities. J. Biol. Chem. 256 : 11992-11995.
14. Serdyuk, A. P., and R. E. Morton.1999.Lipid transfer inhibitor protein defines the participation of lipoproteins in lipid transfer reactions: CETP has no preference for cholesteryl esters in HDL versus LDL. Arterioscler. Thromb. Vasc. Biol. 19 : 718-726.
15. Pattnaik, N. M., A. Montes, L. B. Hughes, and D. B. Zilversmit.978. Cholesteryl ester exchange protein in human plasma: isolation and characterization. Biochim. Biophys. Acta.530 : 428-438.
16. Morton, R. E., and D. B. Zilversmit.1981.The separation of apolipoprotein D from cholesteryl ester transfer protein. Biochim. Biophys. Acta.663 : 350-355.
17. Peterson, G. L. 1977.A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal. Biochem. 83 : 346-356.
18. Bartlett, G. R. 1959.Phosphorus assay in column chromatography. J. Biol. Chem. 234 : 466-468.
19. Morton, R. E., H. M. Gnizak, D. J. Greene, K-H. Cho, and V. M. Paromov.2008.Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects. J. Lipid Res. 49 : 127-135.
20. Wang, S., L. Deng, R. W. Milne, and A. R. Tall.1992.Identification of a sequence within the C-terminal 26 amino acids of cholesteryl ester transfer protein responsible for binding a neutralizing monoclonal antibody and necessary for neutral lipid transfer activity. J. Biol. Chem. 267 : 17487-17490.
21. Swenson, T. L., J. S. Simmons, C. B. Hesler, C. Bisgaier, and A. R. Tall.1987.Cholesteryl ester transfer protein is secreted by Hep G2 cells and contains asparagine-linked carbohydrate and sialic acid. J. Biol. Chem. 262 : 16271-16274.
22. Stevenson, S. C., S. Wang, L. Deng, and A. R. Tall.1993.Human plasma cholesteryl ester transfer protein consists of a mixture of two forms reflecting variable glycosylation at asparagine 341. Biochemistry.32 : 5121-5126.
23. Kotake, H., L. B. Agellon, and S. Yokoyama.1997.Modification of the N-terminal cysteine of plasma cholesteryl ester transfer protein selectively inhibits triglyceride transfer activity. Biochim. Biophys. Acta.1347 : 69-74.
24. Morton, R. E. 1988.Interaction of plasma-derived lipid transfer protein with macrophages in culture. J. Lipid Res. 29 : 1367-1377.
25. Tall, A. 1995.Plasma lipid transfer proteins. Annu. Rev. Biochem. 64 : 235-257.
26. Morton, R. E., and D. B. Zilversmit.1983.Inter-relationship of lipids transferred by the lipid-transfer protein isolated from human lipoprotein-deficient plasma. J. Biol. Chem. 258 : 11751-11757.
27. Weinberg, R. B., V. R. Cook, J. B. Jones, P. Kussie, and A. R. Tall.994.Interfacial properties of recombinant human cholesterol ester transfer protein. J. Biol. Chem. 269 : 29588-29591.
28. Morton, R. E., and J. V. Steinbrunner.1990.Concentration of neutral lipids in the phospholipid surface of substrate particles determines lipid transfer protein activity. J. Lipid Res. 31 : 1559-1567.
29. Morton, R. E., and D. J. Greene.2003.The surface cholesteryl ester content of donor and acceptor particles regulates CETP: a liposome-based approach to assess the substrate properties of lipoproteins. J. Lipid Res. 44 : 1364-1372.
30. Marotti, K. R., C. K. Castle, Y. P. Boyle, A. H. Lin, R. W. Murray, and G. W. Melchior.1993.Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein. Nature.364 : 73-75.
31. Hayek, T., L. Masucci-Magoulas, X. Jiang, A. Walsh, E. Rubin, J. L. Breslow, and A. R. Tall.1995.Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. J. Clin. Invest. 96 : 2071-2074.
32. Okamoto, H., F. Yonemori, K. Wakitani, T. Minowa, K. Maeda, and H. Shinkai.2000.A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature.406 : 203-207.
33. Liu, X. Q., and J. D. Bagdade.1995.Neutral lipid mass transfer among lipoproteins in plasma from normolipidemic subjects is not an equimolar heteroexchange. J. Lipid Res. 36 : 2574-2579.
34. Hopkins, G. J., and P. J. Barter.1982.Dissociation of the in vitro transfers of esterified cholesterol and triglyceride between human lipoproteins. Metabolism.31 : 78-81.
35. Morton, R. E. 1999.Cholesteryl ester transfer protein and its plasma regulator: lipid transfer inhibitor protein. Curr. Opin. Lipidol. 10 : 321-327.