Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Yamamoto, Hideaki ^a,b   Maruo, Tomohiko ^a,b   Majima, Takashi ^b,c,d   Ishizaki, Hiroyoshi ^b,d   Tanaka Okamoto, Miki ^b,d   Miyoshi, Jun ^b,d   Mandai, Kenji ^a,b   Takai, Yoshimi ^a,b,c  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; AFADIN; NECTIN 1; NERVE CELL ADHESION MOLECULE; UNCLASSIFIED DRUG;

AFADIN GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN AQUEDUCT; BRAIN THIRD VENTRICLE; CELL JUNCTION; CELL LOSS; CONTROLLED STUDY; EMBRYO; EPENDYMA CELL; GENE DELETION; GENE FUNCTION; GENE INACTIVATION; HYDROCEPHALUS; MACROGLIA; MESENCEPHALON; MOUSE; NERVE CELL DIFFERENTIATION; NERVE CELL LESION; NEUROPATHOLOGY; NONHUMAN; PROTEIN LOCALIZATION;

ADHERENS JUNCTIONS; ANIMALS; CEREBRAL AQUEDUCT; DISEASE MODELS, ANIMAL; EPENDYMOGLIAL CELLS; GENE DELETION; HYDROCEPHALUS; MESENCEPHALON; MICE; MICE, KNOCKOUT; MICROFILAMENT PROTEINS; NEURONS; PHENOTYPE; PROTEIN TRANSPORT; THIRD VENTRICLE;

EID: 84893360335     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080356     Document Type: Article

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