Alkylphosphocholines as promising antitumor agents: Exploring the role of structural features on the hemolytic potential

Molecular Informatics

Volumn 33, Issue 1, 2014, Pages 53-64

  De Sa, Matheus Malta ^a   Pasqualoto, Kerly Fernanda Mesquita ^b   Modestia, Silvestre Massimo ^a   Rangel Yagui, Carlota O ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

Author keywords

Alkylphosphocholines; Antitumor agents; Exploratory data analysis; Hemolytic potential; Molecular modeling

Indexed keywords

BLOOD;

ALKYL CHAIN; ALKYLPHOSPHOCHOLINE; ANTITUMOUR AGENTS; CATIONICS; CELLULAR MEMBRANES; EXPLORATORY DATA ANALYSIS; HAEMOLYSIS; HEAD GROUPS; HEMOLYTIC POTENTIAL; STRUCTURAL FEATURE;

CELL MEMBRANES;

ADAMANTYL DERIVATIVE; ALKYL GROUP; ALKYLPHOSPHOCHOLINE DERIVATIVE; AMMONIUM DERIVATIVE; ANTINEOPLASTIC AGENT; CYCLOPENTADECYL DERIVATIVE; HEMOLYTIC AGENT; MILTEFOSINE; MORPHOLINE DERIVATIVE; N METHYLMORPHOLINE DERIVATIVE; N METHYLPIPERIDINE DERIVATIVE; N,N,N TRIMETHYLAMMONIUM DERIVATIVE; PHOSPHORYLCHOLINE; PIPERIDINE DERIVATIVE; TRANS N,N,N TRIMETHYLCYCLOHEXANAMINE DERIVATIVE; TRANS N,N,N TRIMETHYLCYCLOPENTANAMINE DERIVATIVE; TRIMETHYLAMMONIUM SALT DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMOMETRIC ANALYSIS; DRUG STRUCTURE; MOLECULAR DYNAMICS; PHYLOGENETIC TREE; PRIORITY JOURNAL; THERMODYNAMICS;

EID: 84893291557     PISSN: 18681743     EISSN: 18681751     Source Type: Journal    
DOI: 10.1002/minf.201300124     Document Type: Article

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