HGF accelerates wound healing by promoting the dedifferentiation of epidermal cells through β 1 -Integrin/ILK pathway

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Li, Jin Feng ^a   Duan, Hai Feng ^b   Wu, Chu Tse ^b   Zhang, Da Jin ^c   Deng, Youping ^d   Yin, Hong Lei ^a   Han, Bing ^a   Gong, Hui Cui ^a   Wang, Hong Wei ^e   Wang, Yun Liang ^a  

^a PLA 148th Hospital   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c NAVY GENERAL HOSPITAL   (China)

^d WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^e UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; INTEGRIN LINKED KINASE; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; INTEGRIN-LINKED KINASE; PROTEIN SERINE THREONINE KINASE;

ACCELERATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEDIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSKELETON; EPIDERMIS CELL; EPITHELIZATION; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; WOUND HEALING; ANIMAL; DRUG EFFECT; EPITHELIUM CELL; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ANIMALS; ANTIGENS, CD29; CELL DEDIFFERENTIATION; DIABETES MELLITUS, EXPERIMENTAL; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HEPATOCYTE GROWTH FACTOR; PROTEIN-SERINE-THREONINE KINASES; RATS; SIGNAL TRANSDUCTION; WOUND HEALING;

EID: 84893184012     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/470418     Document Type: Article

References (29)

1. Krafts K. P., Tissue repair: the hidden drama. Organogenesis 2010 6 4 225 233 2-s2.0-77956404516 10.4161/org.6.4.12555
2. Richards J., Stiffness in healing fractures. Critical Reviews in Biomedical Engineering 1987 15 2 145 185 2-s2.0-0023516951
3. Werner S., Grose R., Regulation of wound healing by growth factors and cytokines. Physiological Reviews 2003 83 3 835 870 2-s2.0-0038676258 (Pubitemid 36828927)
4. Jones P. H., Harper S., Watt F. M., Stem cell patterning and fate in human epidermis. Cell 1995 80 1 83 93 2-s2.0-0028888316 10.1016/0092-8674(95) 90453-0
5. Hannigan G. E., Leung-Hagesteijn C., Fitz-Gibbon L., Coppolino M. G., Radeva G., Filmus J., Bell J. C., Dedhar S., Regulation of cell adhesion and anchorage-dependent growth by a new β 1-integrin-linked protein kinase. Nature 1996 379 6560 91 96 2-s2.0-0030026679 10.1038/379091a0 (Pubitemid 26008142)
6. Conway K., Price P., Harding K. G., Jiang W. G., The molecular and clinical impact of hepatocyte growth factor, its receptor, activators, and inhibitors in wound healing. Wound Repair and Regeneration 2006 14 1 2 10 2-s2.0-33644887722 10.1111/j.1743-6109.2005.00081.x
7. Matsumoto K., Nakamura T., Hepatocyte growth factor (HGF) as a tissue organizer for organogenesis and regeneration. Biochemical and Biophysical Research Communications 1997 239 3 639 644 2-s2.0-0031590435 10.1006/bbrc.1997.7517 (Pubitemid 27504153)
8. Nakanishi K., Uenoyama M., Tomita N., Morishita R., Kaneda Y., Ogihara T., Matsumoto K., Nakamura T., Maruta A., Matsuyama S., Kawai T., Aurues T., Hayashi T., Ikeda T., Gene transfer of human hepatocyte growth factor into rat skin wounds mediated by liposomes coated with the Sendai virus (hemagglutinating virus of Japan). The American Journal of Pathology 2002 161 5 1761 1772 2-s2.0-0036840273 10.1016/S0002-9440(10)64453-7 (Pubitemid 35265534)
9. Islam M. S., Zhou H., Isolation and characterization of putative epidermal stem cells derived from Cashmere goat fetus. European Journal of Dermatology 2007 17 4 302 308 2-s2.0-34447313430 10.1684/ejd.2007.0204 (Pubitemid 47051544)
10. Tan D. W., Jensen K. B., Trotter M. W., Connelly J. T., Broad S., Watt F. M., Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells. Development 2013 140 7 1433 1444 10.1242/dev.087551
11. Zhang C., Fu X., Chen P., Bao X., Li F., Sun X., Lei Y., Cai S., Sun T., Sheng Z., Dedifferentiation derived cells exhibit phenotypic and functional characteristics of epidermal stem cells. Journal of Cellular and Molecular Medicine 2010 14 5 1135 1145 2-s2.0-77954715169 10.1111/j.1582-4934.2009.00765.x
12. Sharma A. K., Bharti S., Ojha S., Bhatia J., Kumar N., Ray R., Kumari S., Arya D. S., Up-regulation of PPAR γ heat shock protein-27 and -72 by naringin attenuates insulin resistance, β -cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes. British Journal of Nutrition 2011 106 11 1713 1723 2-s2.0-82255195245 10.1017/S000711451100225X
13. Zhang Z., Zhao M., Wang J., Ding Y., Dai X., Li Y., Oral administration of skin gelatin isolated from chum salmon (Oncorhynchus keta) enhances wound healing in diabetic rats. Marine Drugs 2011 9 5 696 711 2-s2.0-79957639603 10.3390/md9050696
14. Guo L., Yu W., Li X., Zhao G., Liang J., He P., Wang K., Zhou P., Jiang Y., Zhao M., Targeting of integrin-linked kinase with a small interfering RNA suppresses progression of experimental proliferative vitreoretinopathy. Experimental Eye Research 2008 87 6 551 560 2-s2.0-56649100554 10.1016/j.exer.2008.09.008
15. Tan N. S., Michalik L., Di-Poï N., Desvergne B., Wahli W., Critical roles of the nuclear receptor PPAR β (peroxisome-proliferator-activated receptor β) in skin wound healing. Biochemical Society Transactions 2004 32 1 97 102 2-s2.0-1442308951 10.1042/BST0320097 (Pubitemid 38283023)
16. Tarui T., Majumdar M., Miles L. A., Ruf W., Takada Y., Plasmin-induced migration of endothelial cells: a potential target for the anti-angiogenic action of angiostatin. The Journal of Biological Chemistry 2002 277 37 33564 33570 2-s2.0-0037072784 10.1074/jbc.M205514200
17. Kan M., Zhang G., Zarnegar R., Michalopoulos G., Myoken Y., McKeehan W. L., Stevens J. L., Hepatocyte growth factor/hepatopoietin A stimulates the growth of rat kidney proximal tubule epithelial cells (RPTE), rat nonparenchymal liver cells, human melanoma cells, mouse keratinocytes and stimulates anchorage-independent growth of SV-40 transformed RPTE. Biochemical and Biophysical Research Communications 1991 174 1 331 337 2-s2.0-0026010993 10.1016/0006-291X(91)90524-B
18. Martin P., Wound healing-aiming for perfect skin regeneration. Science 1997 276 5309 75 81 2-s2.0-0030934532 10.1126/science.276.5309.75 (Pubitemid 27161246)
19. Lau K., Paus R., Tiede S., Day P., Bayat A., Exploring the role of stem cells in cutaneous wound healing. Experimental Dermatology 2009 18 11 921 933 2-s2.0-70350751513 10.1111/j.1600-0625.2009.00942.x
20. Miller S. J., Burke E. M., Rader M. D., Coulombe P. A., Lavker R. M., Re-epithelialization of porcine skin by the sweat apparatus. Journal of Investigative Dermatology 1998 110 1 13 19 2-s2.0-0031951734 10.1046/j.1523-1747.1998.00087.x (Pubitemid 28086056)
21. Roh C., Lyle S., Cutaneous stem cells and wound healing. Pediatric Research 2006 59 4, part 2 100R 103R 2-s2.0-33646715610 10.1203/01.pdr. 0000203572.51876.ba (Pubitemid 43740043)
22. Li H., Fu X., Zhang L., Sun T., Wang J., In vivo dedifferentiation of human epidermal cells. Cell Biology International 2007 31 11 1436 1441 2-s2.0-34548479554 10.1016/j.cellbi.2007.05.016 (Pubitemid 47371095)
23. Lowry W. E., Richter L., Yachechko R., Pyle A. D., Tchieu J., Sridharan R., Clark A. T., Plath K., Generation of human induced pluripotent stem cells from dermal fibroblasts. Proceedings of the National Academy of Sciences of the United States of America 2008 105 8 2883 2888 2-s2.0-41349090105 10.1073/pnas.0711983105 (Pubitemid 351723638)
24. Yu J., Vodyanik M. A., Smuga-Otto K., Antosiewicz-Bourget J., Frane J. L., Tian S., Nie J., Jonsdottir G. A., Ruotti V., Stewart R., Slukvin I. I., Thomson J. A., Induced pluripotent stem cell lines derived from human somatic cells. Science 2007 318 5858 1917 1920 2-s2.0-36749043230 10.1126/science. 1151526
25. Pivarcsi A., Széll M., Kemény L., Dobozy A., Bata-Csörgo Z., Serum factors regulate the expression of the proliferation-related genes 5 integrin and keratin 1, but not keratin 10, in HaCat keratinocytes. Archives of Dermatological Research 2001 293 4 206 213 2-s2.0-0035033671 10.1007/s004030100217 (Pubitemid 32391427)
26. Fu X., Sun X., Sun T., Epidermal growth factor induce the epithelial stem cell island formation in the regenerated epidermis. Zhonghua Yi Xue Za Zhi 2001 81 12 733 736 2-s2.0-0035948468
27. McDonald P. C., Fielding A. B., Dedhar S., Integrin-linked kinase-essential roles in physiology and cancer biology. Journal of Cell Science 2008 121 19 3121 3132 2-s2.0-47749087950 10.1242/jcs.017996
28. Xie W., Li F., Kudlow J. E., Wu C., Expression of the integrin-linked kinase (ILK) in mouse skin: loss of expression in suprabasal layers of the epidermis and up-regulation by erbB-2. The American Journal of Pathology 1998 153 2 367 372 2-s2.0-0031876301 10.1016/S0002-9440(10)65580-0 (Pubitemid 28373648)
29. Serrano I., Díez-Marqués M. L., Rodríguez-Puyol M., Integrin-linked kinase (ILK) modulates wound healing through regulation of hepatocyte growth factor (HGF). Experimental Cell Research 2012 318 19 2470 2481 10.1016/j.yexcr.2012.08.001