메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

Changes in liraglutide-induced body composition are related to modifications in plasma cardiac natriuretic peptides levels in obese type 2 diabetic patients

Author keywords

Body composition; Cardiac natriuretic peptides; Liraglutide; Weight loss

Indexed keywords

ADULT; ATRIAL NATRIURETIC FACTOR; BIOLOGICAL MARKERS; BODY COMPOSITION; DIABETES MELLITUS, TYPE 2; FEMALE; FOLLOW-UP STUDIES; GLUCAGON-LIKE PEPTIDE 1; HUMANS; HYPOGLYCEMIC AGENTS; MALE; MIDDLE AGED; NATRIURETIC PEPTIDE, BRAIN; NATRIURETIC PEPTIDES; OBESITY; PROSPECTIVE STUDIES;

EID: 84893183343     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/1475-2840-13-36     Document Type: Article
Times cited : (70)

References (45)
  • 1
    • 33846422032 scopus 로고    scopus 로고
    • Obesity and diabetes in the developing world-a growing challenge
    • 10.1056/NEJMp068177, 17229948
    • Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world-a growing challenge. N Engl J Med 2007, 356:213-215. 10.1056/NEJMp068177, 17229948.
    • (2007) N Engl J Med , vol.356 , pp. 213-215
    • Hossain, P.1    Kawar, B.2    El Nahas, M.3
  • 2
    • 84874775448 scopus 로고    scopus 로고
    • Impact of waist circumference and body mass index on risk of cardiometabolic disorder and cardiovascular disease in Chinese adults: a national diabetes and metabolic disorders survey
    • 10.1371/journal.pone.0057319, 3592870, 23520466, China National Diabetes and Metabolic Disorders Study Group
    • Hou X, Lu J, Weng J, Ji L, Shan Z, Liu J, Tian H, Ji Q, Zhu D, Ge J, Lin L, Chen L, Guo X, Zhao Z, Li Q, Zhou Z, Shan G, Yang Z, Yang W, Jia W. China National Diabetes and Metabolic Disorders Study Group Impact of waist circumference and body mass index on risk of cardiometabolic disorder and cardiovascular disease in Chinese adults: a national diabetes and metabolic disorders survey. PLoS One 2013, 8:e57319. 10.1371/journal.pone.0057319, 3592870, 23520466, China National Diabetes and Metabolic Disorders Study Group.
    • (2013) PLoS One , vol.8
    • Hou, X.1    Lu, J.2    Weng, J.3    Ji, L.4    Shan, Z.5    Liu, J.6    Tian, H.7    Ji, Q.8    Zhu, D.9    Ge, J.10    Lin, L.11    Chen, L.12    Guo, X.13    Zhao, Z.14    Li, Q.15    Zhou, Z.16    Shan, G.17    Yang, Z.18    Yang, W.19    Jia, W.20    more..
  • 3
    • 79958094404 scopus 로고    scopus 로고
    • The once-daily human glucagon-like peptide-1 (GLP-1) analog liraglutide improves postprandial glucose levels in type 2 diabetes patients
    • 10.1007/s12325-010-0110-x, 21340616
    • Flint A, Kapitza C, Hindsberger C, Zdravkovic M. The once-daily human glucagon-like peptide-1 (GLP-1) analog liraglutide improves postprandial glucose levels in type 2 diabetes patients. Adv Ther 2011, 28:213-226. 10.1007/s12325-010-0110-x, 21340616.
    • (2011) Adv Ther , vol.28 , pp. 213-226
    • Flint, A.1    Kapitza, C.2    Hindsberger, C.3    Zdravkovic, M.4
  • 4
    • 67651173077 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus
    • 10.1038/nrendo.2009.48, 19444259
    • Lovshin JA, Drucker DJ. Incretin-based therapies for type 2 diabetes mellitus. Nat Rev Endocrinol 2009, 5:262-269. 10.1038/nrendo.2009.48, 19444259.
    • (2009) Nat Rev Endocrinol , vol.5 , pp. 262-269
    • Lovshin, J.A.1    Drucker, D.J.2
  • 5
    • 62449169287 scopus 로고    scopus 로고
    • Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes
    • 10.2337/dc08-1355, 2606836, 18931095, LEAD-2 Study Group
    • Nauck M, Frid A, Hermansen K, Shah NS, Tankova T, Mitha IH, Zdravkovic M, Düring M, Matthews DR. LEAD-2 Study Group Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin in type 2 diabetes. Diabetes Care 2009, 32:84-90. 10.2337/dc08-1355, 2606836, 18931095, LEAD-2 Study Group.
    • (2009) Diabetes Care , vol.32 , pp. 84-90
    • Nauck, M.1    Frid, A.2    Hermansen, K.3    Shah, N.S.4    Tankova, T.5    Mitha, I.H.6    Zdravkovic, M.7    Düring, M.8    Matthews, D.R.9
  • 6
    • 59449101432 scopus 로고    scopus 로고
    • Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial
    • 10.1016/S0140-6736(08)61246-5, 18819705, LEAD-3 (Mono) Study Group
    • Garber A, Henry R, Ratner R, Garcia-Hernandez PA, Rodriguez-Pattzi H, Olvera-Alvarez I, Hale PM, Zdravkovic M, Bode B. LEAD-3 (Mono) Study Group Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial. Lancet 2009, 373:473-481. 10.1016/S0140-6736(08)61246-5, 18819705, LEAD-3 (Mono) Study Group.
    • (2009) Lancet , vol.373 , pp. 473-481
    • Garber, A.1    Henry, R.2    Ratner, R.3    Garcia-Hernandez, P.A.4    Rodriguez-Pattzi, H.5    Olvera-Alvarez, I.6    Hale, P.M.7    Zdravkovic, M.8    Bode, B.9
  • 7
    • 70450190143 scopus 로고    scopus 로고
    • Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue
    • 10.1111/j.1463-1326.2009.01158.x, 19930006, LEAD-2 and LEAD-3 Study Groups
    • Jendle J, Nauck MA, Matthews DR, Frid A, Hermansen K, Düring M, Zdravkovic M, Strauss BJ, Garber AJ. LEAD-2 and LEAD-3 Study Groups Weight loss with liraglutide, a once-daily human glucagon-like peptide-1 analogue for type 2 diabetes treatment as monotherapy or added to metformin, is primarily as a result of a reduction in fat tissue. Diabetes Obes Metab 2009, 11:1163-1172. 10.1111/j.1463-1326.2009.01158.x, 19930006, LEAD-2 and LEAD-3 Study Groups.
    • (2009) Diabetes Obes Metab , vol.11 , pp. 1163-1172
    • Jendle, J.1    Nauck, M.A.2    Matthews, D.R.3    Frid, A.4    Hermansen, K.5    Düring, M.6    Zdravkovic, M.7    Strauss, B.J.8    Garber, A.J.9
  • 8
    • 84868700326 scopus 로고    scopus 로고
    • Efficacy and safety comparison between liraglutide as add-on therapy to insulin and insulin dose-increase in Chinese subjects with poorly controlled type 2 diabetes and abdominal obesity
    • 10.1186/1475-2840-11-142, 3533748, 23153177
    • Li CJ, Li J, Zhang QM, Lv L, Chen R, Lv CF, Yu P, Yu DM. Efficacy and safety comparison between liraglutide as add-on therapy to insulin and insulin dose-increase in Chinese subjects with poorly controlled type 2 diabetes and abdominal obesity. Cardiovasc Diabetol 2012, 11:142. 10.1186/1475-2840-11-142, 3533748, 23153177.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 142
    • Li, C.J.1    Li, J.2    Zhang, Q.M.3    Lv, L.4    Chen, R.5    Lv, C.F.6    Yu, P.7    Yu, D.M.8
  • 9
    • 0034951506 scopus 로고    scopus 로고
    • The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesity
    • Flint A, Raben A, Ersbøll AK, Holst JJ, Astrup A. The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesity. Int J Obes 2001, 25:781-792.
    • (2001) Int J Obes , vol.25 , pp. 781-792
    • Flint, A.1    Raben, A.2    Ersbøll, A.K.3    Holst, J.J.4    Astrup, A.5
  • 10
    • 0032966882 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
    • Gutzwiller JP, Drewe J, Göke B, Schmidt H, Rohrer B, Lareida J, Beglinger C. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am J Physiol 1999, 276:1541-1544.
    • (1999) Am J Physiol , vol.276 , pp. 1541-1544
    • Gutzwiller, J.P.1    Drewe, J.2    Göke, B.3    Schmidt, H.4    Rohrer, B.5    Lareida, J.6    Beglinger, C.7
  • 11
    • 0035432607 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment
    • 10.2337/diacare.24.8.1416, 11473079
    • Larsen J, Hylleberg B, Ng K, Damsbo P. Glucagon-like peptide-1 infusion must be maintained for 24 h/day to obtain acceptable glycemia in type 2 diabetic patients who are poorly controlled on sulphonylurea treatment. Diabetes Care 2001, 24:1416-1421. 10.2337/diacare.24.8.1416, 11473079.
    • (2001) Diabetes Care , vol.24 , pp. 1416-1421
    • Larsen, J.1    Hylleberg, B.2    Ng, K.3    Damsbo, P.4
  • 12
    • 70350619609 scopus 로고    scopus 로고
    • Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
    • 10.1016/S0140-6736(09)61375-1, 19853906, NN8022-1807 Study Group
    • Astrup A, Rössner S, Van Gaal L, Rissanen A, Niskanen L, Al Hakim M, Madsen J, Rasmussen MF, Lean ME. NN8022-1807 Study Group Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009, 374:1606-1616. 10.1016/S0140-6736(09)61375-1, 19853906, NN8022-1807 Study Group.
    • (2009) Lancet , vol.374 , pp. 1606-1616
    • Astrup, A.1    Rössner, S.2    Van Gaal, L.3    Rissanen, A.4    Niskanen, L.5    Al Hakim, M.6    Madsen, J.7    Rasmussen, M.F.8    Lean, M.E.9
  • 14
    • 0031049302 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide 1 (7-36 amide) on whole-body protein metabolism in healthy man
    • Shalev A, Holst JJ, Keller U. Effects of glucagon-like peptide 1 (7-36 amide) on whole-body protein metabolism in healthy man. Eur J Clin Invest 1997, 27:10-16.
    • (1997) Eur J Clin Invest , vol.27 , pp. 10-16
    • Shalev, A.1    Holst, J.J.2    Keller, U.3
  • 15
    • 84877317750 scopus 로고    scopus 로고
    • GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure
    • 10.1038/nm.3128, 23542788
    • Kim M, Platt MJ, Shibasaki T, Quaggin SE, Backx PH, Seino S, Simpson JA, Drucker DJ. GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure. Nature Med 2013, 19:567-575. 10.1038/nm.3128, 23542788.
    • (2013) Nature Med , vol.19 , pp. 567-575
    • Kim, M.1    Platt, M.J.2    Shibasaki, T.3    Quaggin, S.E.4    Backx, P.H.5    Seino, S.6    Simpson, J.A.7    Drucker, D.J.8
  • 16
    • 0033936322 scopus 로고    scopus 로고
    • Natriuretic peptides: a new lipolytic pathway in human adipocytes
    • 10.1096/fj.14.10.1345, 10877827
    • Sengenès C, Berlan M, De Glisezinski I, Lafontan M, Galitzky J. Natriuretic peptides: a new lipolytic pathway in human adipocytes. FASEB J 2000, 14:1345-1351. 10.1096/fj.14.10.1345, 10877827.
    • (2000) FASEB J , vol.14 , pp. 1345-1351
    • Sengenès, C.1    Berlan, M.2    De Glisezinski, I.3    Lafontan, M.4    Galitzky, J.5
  • 19
    • 1042267237 scopus 로고    scopus 로고
    • Impact of obesity on plasma natriuretic peptide levels
    • 10.1161/01.CIR.0000112582.16683.EA, 14769680
    • Wang TJ, Larson MG, Levy D, Benjamin EJ, Leip EP, Wilson PW, Vasan RS. Impact of obesity on plasma natriuretic peptide levels. Circulation 2004, 109:594-600. 10.1161/01.CIR.0000112582.16683.EA, 14769680.
    • (2004) Circulation , vol.109 , pp. 594-600
    • Wang, T.J.1    Larson, M.G.2    Levy, D.3    Benjamin, E.J.4    Leip, E.P.5    Wilson, P.W.6    Vasan, R.S.7
  • 22
    • 84878240625 scopus 로고    scopus 로고
    • Banting Lecture 2012: Regulation of adipogenesis: toward new therapeutics for metabolic disease
    • 10.2337/db12-1665, 23704518
    • Spiegelman BM. Banting Lecture 2012: Regulation of adipogenesis: toward new therapeutics for metabolic disease. Diabetes 2013, 62:1774-1782. 10.2337/db12-1665, 23704518.
    • (2013) Diabetes , vol.62 , pp. 1774-1782
    • Spiegelman, B.M.1
  • 23
    • 4344642711 scopus 로고    scopus 로고
    • Iterindividual variation in abdominal subcutaneous and visceral adipose tissue: influence of measurement site
    • 10.1152/japplphysiol.01200.2003, 15121737
    • Lee S, Janssen I, Ross R. Iterindividual variation in abdominal subcutaneous and visceral adipose tissue: influence of measurement site. J Appl Physiol 2004, 97:948-954. 10.1152/japplphysiol.01200.2003, 15121737.
    • (2004) J Appl Physiol , vol.97 , pp. 948-954
    • Lee, S.1    Janssen, I.2    Ross, R.3
  • 26
    • 24144441285 scopus 로고    scopus 로고
    • Point: visceral adiposity is causally related to insulin resistance
    • 10.2337/diacare.28.9.2322, 16123512
    • Lebovitz HE, Banerji MA. Point: visceral adiposity is causally related to insulin resistance. Diabetes Care 2005, 28:2322-2325. 10.2337/diacare.28.9.2322, 16123512.
    • (2005) Diabetes Care , vol.28 , pp. 2322-2325
    • Lebovitz, H.E.1    Banerji, M.A.2
  • 27
    • 3342984674 scopus 로고    scopus 로고
    • The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycaemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes
    • 10.2337/diacare.27.8.1915, 15277417
    • Harder H, Nielsen L, Tu DT, Astrup A. The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycaemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes. Diabetes Care 2004, 27:1915-1921. 10.2337/diacare.27.8.1915, 15277417.
    • (2004) Diabetes Care , vol.27 , pp. 1915-1921
    • Harder, H.1    Nielsen, L.2    Tu, D.T.3    Astrup, A.4
  • 28
    • 34547905810 scopus 로고    scopus 로고
    • Visceral adipose tissue accumulation differs according to ethnic background: results of the Multicultural Community Health Assessment Trial (M-CHAT)
    • Lear SA, Humphries KH, Kohli S, Chockalingam A, Frohlich JJ, Birmingham CL. Visceral adipose tissue accumulation differs according to ethnic background: results of the Multicultural Community Health Assessment Trial (M-CHAT). Am J Clin Nutr 2007, 86:353-359.
    • (2007) Am J Clin Nutr , vol.86 , pp. 353-359
    • Lear, S.A.1    Humphries, K.H.2    Kohli, S.3    Chockalingam, A.4    Frohlich, J.J.5    Birmingham, C.L.6
  • 29
    • 84862299162 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide-1 receptor agonists on body weight: a metaanalysis
    • 3362858, 22675341
    • Monami M, Dicembrini I, Marchionni N, Rotella CM, Mannucci E. Effects of glucagon-like peptide-1 receptor agonists on body weight: a metaanalysis. Exp Diabetes Res 2012, 2012:672658. 3362858, 22675341.
    • (2012) Exp Diabetes Res , vol.2012 , pp. 672658
    • Monami, M.1    Dicembrini, I.2    Marchionni, N.3    Rotella, C.M.4    Mannucci, E.5
  • 30
    • 33847072735 scopus 로고    scopus 로고
    • Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not
    • 10.2337/db06-0565, 17192459
    • Raun K, Von Voss P, Gotfredsen CF, Golozoubova V, Rolin B, Knudsen LB. Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not. Diabetes 2007, 56:8-15. 10.2337/db06-0565, 17192459.
    • (2007) Diabetes , vol.56 , pp. 8-15
    • Raun, K.1    Von Voss, P.2    Gotfredsen, C.F.3    Golozoubova, V.4    Rolin, B.5    Knudsen, L.B.6
  • 31
    • 34547951456 scopus 로고    scopus 로고
    • Liraglutide, a once-daily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs
    • 10.1038/oby.2007.204, 17636089
    • Raun K, Von Voss P, Knudsen LB. Liraglutide, a once-daily human glucagon-like peptide-1 analog, minimizes food intake in severely obese minipigs. Obesity (Silver Spring) 2007, 15:1710-1716. 10.1038/oby.2007.204, 17636089.
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 1710-1716
    • Raun, K.1    Von Voss, P.2    Knudsen, L.B.3
  • 33
    • 79959675075 scopus 로고    scopus 로고
    • Comparative effects of the long-acting glp-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats
    • 10.1038/oby.2011.50, 21415845
    • Hayes MR, Kanoski SE, Alhadeff AL, Grill HJ. Comparative effects of the long-acting glp-1 receptor ligands, liraglutide and exendin-4, on food intake and body weight suppression in rats. Obesity (Silver Spring) 2011, 19:1342-1349. 10.1038/oby.2011.50, 21415845.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 1342-1349
    • Hayes, M.R.1    Kanoski, S.E.2    Alhadeff, A.L.3    Grill, H.J.4
  • 35
    • 84866152721 scopus 로고    scopus 로고
    • Efficacy of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, on body weight, eating behavior, and glycemic control, in Japanese obese type 2 diabetes
    • 10.1186/1475-2840-11-107, 3459720, 22973968
    • Fujishima Y, Maeda N, Inoue K, Kashine S, Nishizawa H, Hirata A, Kozawa J, Yasuda T, Okita K, Imagawa A, Funahashi T, Shimomura I. Efficacy of liraglutide, a glucagon-like peptide-1 (GLP-1) analogue, on body weight, eating behavior, and glycemic control, in Japanese obese type 2 diabetes. Cardiovasc Diabetol 2012, 11:107. 10.1186/1475-2840-11-107, 3459720, 22973968.
    • (2012) Cardiovasc Diabetol , vol.11 , pp. 107
    • Fujishima, Y.1    Maeda, N.2    Inoue, K.3    Kashine, S.4    Nishizawa, H.5    Hirata, A.6    Kozawa, J.7    Yasuda, T.8    Okita, K.9    Imagawa, A.10    Funahashi, T.11    Shimomura, I.12
  • 36
    • 82355160875 scopus 로고    scopus 로고
    • Short-term effects of liraglutide on visceral fat adiposity, appetite, and food preference: a pilot study of obese Japanese patients with type 2 diabetes
    • 10.1186/1475-2840-10-109, 3260096, 22132774
    • Inoue K, Maeda N, Kashine S, Fujishima Y, Kozawa J, Hiuge-Shimizu A, Okita K, Imagawa A, Funahashi T, Shimomura I. Short-term effects of liraglutide on visceral fat adiposity, appetite, and food preference: a pilot study of obese Japanese patients with type 2 diabetes. Cardiovasc Diabetol 2011, 10:109. 10.1186/1475-2840-10-109, 3260096, 22132774.
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 109
    • Inoue, K.1    Maeda, N.2    Kashine, S.3    Fujishima, Y.4    Kozawa, J.5    Hiuge-Shimizu, A.6    Okita, K.7    Imagawa, A.8    Funahashi, T.9    Shimomura, I.10
  • 37
    • 84863229962 scopus 로고    scopus 로고
    • Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes
    • 10.1172/JCI59701, 3287224, 22307324
    • Bordicchia M, Liu D, Amri EZ, Ailhaud G, Dessì-Fulgheri P, Zhang C, Takahashi N, Sarzani R, Collins S. Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes. J Clin Invest 2012, 122:1022-1036. 10.1172/JCI59701, 3287224, 22307324.
    • (2012) J Clin Invest , vol.122 , pp. 1022-1036
    • Bordicchia, M.1    Liu, D.2    Amri, E.Z.3    Ailhaud, G.4    Dessì-Fulgheri, P.5    Zhang, C.6    Takahashi, N.7    Sarzani, R.8    Collins, S.9
  • 39
    • 77952421379 scopus 로고    scopus 로고
    • Relation of B-type natriuretic peptide levels to body mass index after comprehensive lifestyle changes
    • 10.1016/j.amjcard.2010.01.016, 20494664
    • Chainani-Wu N, Weidner G, Purnell DM, Frenda S, Merritt-Worden T, Kemp C, Kersh E, Ornish D. Relation of B-type natriuretic peptide levels to body mass index after comprehensive lifestyle changes. Am J Cardiol 2010, 105:1570-1576. 10.1016/j.amjcard.2010.01.016, 20494664.
    • (2010) Am J Cardiol , vol.105 , pp. 1570-1576
    • Chainani-Wu, N.1    Weidner, G.2    Purnell, D.M.3    Frenda, S.4    Merritt-Worden, T.5    Kemp, C.6    Kersh, E.7    Ornish, D.8
  • 42
    • 0031445294 scopus 로고    scopus 로고
    • Plasma atrial natriuretic peptide and natriuretic peptide receptor gene expression in adipose tissue of normotensive and hypertensive obese patients
    • 10.1097/00004872-199715120-00074, 9488224
    • Dessì-Fulgheri P, Sarzani R, Tamburrini P, Moraca A, Espinosa E, Cola G, Giantomassi L, Rappelli A. Plasma atrial natriuretic peptide and natriuretic peptide receptor gene expression in adipose tissue of normotensive and hypertensive obese patients. J Hypertens 1997, 15:1695-1699. 10.1097/00004872-199715120-00074, 9488224.
    • (1997) J Hypertens , vol.15 , pp. 1695-1699
    • Dessì-Fulgheri, P.1    Sarzani, R.2    Tamburrini, P.3    Moraca, A.4    Espinosa, E.5    Cola, G.6    Giantomassi, L.7    Rappelli, A.8
  • 44
    • 84879039617 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection
    • 10.1186/1475-2840-12-90, 3700838, 23777457
    • Zhao TC. Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection. Cardiovasc Diabetol 2013, 12:90. 10.1186/1475-2840-12-90, 3700838, 23777457.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 90
    • Zhao, T.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.