WLIP derived from Lasiosphaera fenzlii Reich exhibits anti-tumor activity and induces cell cycle arrest through PPAR-γ associated pathways

International Immunopharmacology

Volumn 19, Issue 1, 2014, Pages 37-44

  Meng, Jingjing ^a,b   Fan, Yanhua ^b   Su, Mingzhi ^a   Chen, Congqin ^b   Ren, Tianshu ^a   Wang, Jinhui ^b   Zhao, Qingchun ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; K562 cells; Lasiosphaera fenzlii Reich; Molecular docking; PPAR ; White line inducing principle

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLIN D1; DEPSIPEPTIDE; LUCIFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BCL XL; UNCLASSIFIED DRUG; WHITE LINE INDUCING PRINCIPLE;

AGARICALES; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN K 562; CELL VIABILITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DOWN REGULATION; DRUG ISOLATION; DRUG TARGETING; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION; HUMAN; HUMAN CELL; IC 50; LASIOSPHAERA FENZLII; LEUKEMIA CELL; LUCIFERASE ASSAY; LUNG CANCER; MOLECULAR DOCKING; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY;

APOPTOSIS; K562 CELLS; LASIOSPHAERA FENZLII REICH; MOLECULAR DOCKING; PPAR-Γ; WHITE-LINE-INDUCING PRINCIPLE;

AGARICALES; ANTINEOPLASTIC AGENTS; BCL-X PROTEIN; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; DEPSIPEPTIDES; HUMANS; LIPOPEPTIDES; PPAR GAMMA;

EID: 84893175068     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.12.026     Document Type: Article

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