How citrullination invaded rheumatoid arthritis research

Arthritis Research and Therapy

Volumn 16, Issue 1, 2014, Pages

  Van Venrooij, Walther J ^a   Pruijn, Ger J M ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC CITRULLINATED PEPTIDE ANTIBODY; CYCLIC CITRULLINATED PEPTIDE ANTIBODY 2; HLA DRB1 ANTIGEN; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG; AUTOANTIBODY; AUTOANTIGEN; CITRULLINE; PROTEIN;

AUTOIMMUNITY; CITRULLINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MEDICAL RESEARCH; NONHUMAN; NOTE; PATHOPHYSIOLOGY; PHYSIOLOGICAL PROCESS; PROTEIN SYNTHESIS; RHEUMATOID ARTHRITIS; SYNOVIUM; ANIMAL; IMMUNOLOGY; METABOLISM;

ANIMALS; ARTHRITIS, RHEUMATOID; AUTOANTIBODIES; AUTOANTIGENS; CITRULLINE; HUMANS; PROTEINS;

EID: 84893117193     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar4458     Document Type: Note

References (19)

1. Simon M, Girbal E, Sebbag M, Gomes-Daudrix V, Vincent C, Salama G, Serre G. The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis. J Clin Invest 1993, 92:1387-1393. 10.1172/JCI116713, 288281, 7690781.
2. Hoet RM, Boerbooms AM, Arends M, Ruiter DJ, van Venrooij WJ. Antiperinuclear factor, a marker autoantibody for rheumatoid arthritis: colocalisation of the perinuclear factor and profilaggrin. Ann Rheum Dis 1991, 50:611-618. 10.1136/ard.50.9.611, 1004503, 1718228.
3. Schellekens GA, de Jong BA, van den Hoogen FH, van de Putte LB, van Venrooij WJ. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest 1998, 101:273-281. 10.1172/JCI1316, 508564, 9421490.
4. Schellekens GA, Visser H, de Jong BA, van den Hoogen FH, Hazes JM, Breedveld FC, van Venrooij WJ. The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide. Arthritis Rheum 2000, 43:155-163. 10.1002/1529-0131(200001)43:1<155::AID-ANR20>3.0.CO;2-3, 10643712.
5. van Venrooij WJ, van Beers JJ, Pruijn GJ. Anti-CCP antibodies: the past, the present and the future. Nat Rev Rheumatol 2011, 7:391-398. 10.1038/nrrheum.2011.76, 21647203.
6. Bizzaro N, Pregnolato F, van Boekel MA, Villalta D, Tozzoli R, Tonutti E, Antico A, Borghi MO, Wiik A, Meroni PL. Preliminary evaluation of the first international reference preparation for anticitrullinated peptide antibodies. Ann Rheum Dis 2012, 71:1388-1392. 10.1136/annrheumdis-2011-200693, 22492784.
7. Bizzaro N, Bartoloni E, Morozzi G, Manganelli S, Riccieri V, Sabatini P, Filippini M, Tampoia M, Afeltra A, Sebastiani G, Alpini C, Bini V, Bistoni O, Alunno A, Gerli R. the Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni (FIRMA Group) Anti-cyclic citrullinated peptide antibody titer predicts time to rheumatoid arthritis onset in patients with undifferentiated arthritis: results from a 2-year prospective study. Arthritis Res Ther 2013, 15:R16. 10.1186/ar4148, 3672733, 23339296, the Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni (FIRMA Group).
8. Shi J, Knevel R, Suwannalai P, van der Linden MP, Janssen GM, van Veelen PA, Levarht NE, van der Helm-van Mil AH, Cerami A, Huizinga TW, Toes RE, Trouw LA. Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage. Proc Natl Acad Sci U S A 2011, 108:17372-17377. 10.1073/pnas.1114465108, 3198314, 21987802.
9. Klareskog L, Malmstrom V, Lundberg K, Padyukov L, Alfredsson L. Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis. Sem Immunol 2011, 23:92-98.
10. Quirke AM, Fisher BA, Kinloch AJ, Venables PJ. Citrullination of autoantigens: upstream of TNFalpha in the pathogenesis of rheumatoid arthritis. FEBS Lett 2011, 585:3681-3688. 10.1016/j.febslet.2011.06.006, 21704035.
11. Amara K, Steen J, Murray F, Morbach H, Fernandez-Rodriguez BM, Joshua V, Engström M, Snir O, Israelsson L, Catrina AI, Wardemann H, Corti D, Meffre E, Klareskog L, Malmström V. Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition. J Exp Med 2013, 210:445-455. 10.1084/jem.20121486, 3600900, 23440041.
12. Suwannalai P, van de Stadt LA, Radner H, Steiner G, El-Gabalawy HS, Zijde CM, van Tol MJ, van Schaardenburg D, Huizinga TW, Toes RE, Trouw LA. Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis. Arthritis Rheum 2012, 64:1323-1328. 10.1002/art.33489, 22130974.
13. Harre U, Georgess D, Bang H, Bozec A, Axmann R, Ossipova E, Jakobsson PJ, Baum W, Nimmerjahn F, Szarka E, Sarmay G, Krumbholz G, Neumann E, Toes R, Scherer HU, Catrina AI, Klareskog L, Jurdic P, Schett G. Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J Clin Invest 2012, 122:1791-1802. 10.1172/JCI60975, 3336988, 22505457.
14. Shelef MA, Bennin DA, Mosher DF, Huttenlocher A. Citrullination of fibronectin modulates synovial fibroblast behavior. Arthritis Res Ther 2012, 14:R240. 10.1186/ar4083, 3674601, 23127210.
15. Sokolove J, Zhao X, Chandra PE, Robinson WH. Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcgamma receptor. Arthritis Rheum 2011, 63:53-62. 3015008, 20954191.
16. Ling S, Cline EN, Haug TS, Fox DA, Holoshitz J. Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling. Arthritis Rheum 2013, 65:618-626. 10.1002/art.37814, 23233327.
17. Andrade F, Darrah E, Gucek M, Cole RN, Rosen A, Zhu X. Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation. Arthritis Rheum 2010, 62:1630-1640. 10.1002/art.27439, 2951335, 20201080.
18. Simon D, Simon HU, Yousefi S. Extracellular DNA traps in allergic, infectious, and autoimmune diseases. Allergy 2013, 68:409-416. 10.1111/all.12111, 23409745.
19. Knight JS, Carmona-Rivera C, Kaplan MJ. Proteins derived from neutrophil extracellular traps may serve as self-antigens and mediate organ damage in autoimmune diseases. Front Immunol 2012, 3:380. 3521997, 23248629.