Foot-and-mouth disease virus virulence in cattle is co-determined by viral replication dynamics and route of infection

Virology

Volumn 452-453, Issue , 2014, Pages 12-22

  Arzt, Jonathan ^a   Pacheco, Juan M ^a   Smoliga, George R ^a   Tucker, Meghan T ^a   Bishop, Elizabeth ^a   Pauszek, Steven J ^a   Hartwig, Ethan J ^a   Santos, Teresa de los ^a   Rodriguez, Luis L ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Attenuation; Bovine; Cattle; FMD; FMDV; Foot and mouth; Interferon; Pathogenesis; Virulence; Virus

Indexed keywords

2',5' OLIGOADENYLATE SYNTHETASE; ALPHA INTERFERON; BETA INTERFERON; COMPLEMENTARY DNA; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 7; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE R; VIRUS RNA;

AEROSOL INOCULATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BULLOCK; CATTLE DISEASE; CLINICAL FEATURE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; FOOT AND MOUTH DISEASE; FOOT AND MOUTH DISEASE VIRUS; GENE DOSAGE; HISTOPATHOLOGY; INNATE IMMUNITY; INOCULATION; INTRAEPITHELIAL LINGUAL INOCULATION; MALE; MOLECULAR DYNAMICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TISSUE DISTRIBUTION; VIREMIA; VIRUS CELL INTERACTION; VIRUS DETECTION; VIRUS LOAD; VIRUS MUTANT; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS TRANSMISSION; VIRUS VIRULENCE; WILD TYPE;

ATTENUATION; BOVINE; CATTLE; FMD; FMDV; FOOT-AND-MOUTH; INTERFERON; PATHOGENESIS; VIRULENCE; VIRUS;

ANIMALS; CATTLE; CATTLE DISEASES; FOOT-AND-MOUTH DISEASE; FOOT-AND-MOUTH DISEASE VIRUS; IMMUNITY, INNATE; INTERFERONS; VIRULENCE; VIRUS REPLICATION;

EID: 84893076807     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2014.01.001     Document Type: Article

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