Two interconvertible folds modulate the activity of a DNA aptamer against transferrin receptor

Molecular Therapy Nucleic Acids

Volumn 3, Issue , 2014, Pages e144-

  Porciani, David ^a,b   Signore, Giovanni ^b   Marchetti, Laura ^a   Mereghetti, Paolo ^b   Nifosì, Riccardo ^a   Beltram, Fabio ^a  

^a SCUOLA NORMALE SUPERIORE   (Italy)

^b ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

Aptamer folding; Aptamer rational engineering; Aptamer mediated endocytosis; Transferrin receptor

Indexed keywords

APTAMER; DNA; TRANSFERRIN RECEPTOR;

ANIMAL CELL; ANISOTROPY; ARTICLE; BINDING AFFINITY; CANCER CELL; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA CONFORMATION; ENDOCYTOSIS; FIBROBLAST; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; IN VITRO STUDY; INTERNALIZATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANCREAS CANCER; PANCREAS CARCINOMA; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; RECEPTOR BINDING; STATIC ELECTRICITY; TEMPERATURE DEPENDENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; BIOLOGICAL ACTIVITY; CHROMATOGRAPHY; CLINICAL ASSESSMENT; ENZYME ACTIVITY; PROTEIN DNA INTERACTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS;

EID: 84893054594     PISSN: None     EISSN: 21622531     Source Type: Journal    
DOI: 10.1038/mtna.2013.71     Document Type: Article

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