-
1
-
-
0345596364
-
Toxicity of fluorouracil in patients with advanced colorectal cancer: Effect of administration schedule and prognostic factos
-
Meta-Analysis Group in Cancer. Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factos. J Clin Oncol. 1998;16(11):3537-3541.
-
(1998)
J Clin Oncol
, vol.16
, Issue.11
, pp. 3537-3541
-
-
-
2
-
-
0024595925
-
Clinical pharmacology of 5-fluorouracil
-
Diasio RB, Harris BE. Clinical pharmacology of 5-fluorouracil. Clin Pharmacokinet. 1989;16(4):215-237.
-
(1989)
Clin Pharmacokinet
, vol.16
, Issue.4
, pp. 215-237
-
-
Diasio, R.B.1
Harris, B.E.2
-
3
-
-
37449002083
-
Dihydropyrimidine dehydrogenase deficiency (DPD) in GI malignancies: Experience of 4 years
-
Saif MW, Syrigos K, Mehra R, et al. Dihydropyrimidine dehydrogenase deficiency (DPD) in GI malignancies: experience of 4 years. Pak J Med Sci. 2007;23(6):832-839.
-
(2007)
Pak J Med Sci
, vol.23
, Issue.6
, pp. 832-839
-
-
Saif, M.W.1
Syrigos, K.2
Mehra, R.3
-
4
-
-
0025666730
-
Metabolism of pyrimidine analogues and their nucleosides
-
Daher GC, Harris BE, Diasio RB. Metabolism of pyrimidine analogues and their nucleosides. Pharmacol Ther. 1990;48(2): 189-222.
-
(1990)
Pharmacol Ther
, vol.48
, Issue.2
, pp. 189-222
-
-
Daher, G.C.1
Harris, B.E.2
Diasio, R.B.3
-
5
-
-
0025058867
-
Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion
-
Harris BE, Song R, Soong SJ, Diasio RB. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res. 1990;50(1):197-201.
-
(1990)
Cancer Res
, vol.50
, Issue.1
, pp. 197-201
-
-
Harris, B.E.1
Song, R.2
Soong, S.J.3
Diasio, R.B.4
-
6
-
-
0025990479
-
Severe 5-Fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency: A potentially more common pharmacogenetic syndrome
-
Harris BE, Carpenter JT, Diasio RB. Severe 5-Fluorouracil toxicity secondary to dihydropyrimidine dehydrogenase deficiency: a potentially more common pharmacogenetic syndrome. Cancer. 1991;68(3):499-501.
-
(1991)
Cancer
, vol.68
, Issue.3
, pp. 499-501
-
-
Harris, B.E.1
Carpenter, J.T.2
Diasio, R.B.3
-
7
-
-
0028006858
-
Population study of dihydropyrimidine dehydrogenase in cancer patients
-
Etienne MC, Lagrange JL, Dassonville O, et al. Population study of dihydropyrimidine dehydrogenase in cancer patients. J Clin Oncol. 1994;12(11):2248-2253.
-
(1994)
J Clin Oncol
, vol.12
, Issue.11
, pp. 2248-2253
-
-
Etienne, M.C.1
Lagrange, J.L.2
Dassonville, O.3
-
8
-
-
84875421741
-
Phenotypic profiling of DPYD variations relevant to 5-fluorouracil sensitivity using real-time cellular analysis and in vitro measurement of enzyme activity
-
Offer SM, Wegner NJ, Fossum C, Wang K, Diasio RB. Phenotypic profiling of DPYD variations relevant to 5-fluorouracil sensitivity using real-time cellular analysis and in vitro measurement of enzyme activity. Cancer Res. 2013;73(6):1958-1968.
-
(2013)
Cancer Res
, vol.73
, Issue.6
, pp. 1958-1968
-
-
Offer, S.M.1
Wegner, N.J.2
Fossum, C.3
Wang, K.4
Diasio, R.B.5
-
9
-
-
33947416573
-
5-Fluorouracilrelated severe toxicity: A comparison of different methods for the pretherapeutic detection of dihydropyrimidine dehydrogenase deficiency
-
Boisdron-Celle M, Remaud G, Traore S, et al. 5-Fluorouracilrelated severe toxicity: a comparison of different methods for the pretherapeutic detection of dihydropyrimidine dehydrogenase deficiency. Cancer Lett. 2007;249(2):271-282.
-
(2007)
Cancer Lett
, vol.249
, Issue.2
, pp. 271-282
-
-
Boisdron-Celle, M.1
Remaud, G.2
Traore, S.3
-
10
-
-
33845219798
-
Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance
-
Morel A, Boisdron-Celle M, Fey L, et al. Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance. Mol Cancer Ther. 2006;5(11):2895-2904.
-
(2006)
Mol Cancer Ther
, vol.5
, Issue.11
, pp. 2895-2904
-
-
Morel, A.1
Boisdron-Celle, M.2
Fey, L.3
-
11
-
-
43749114271
-
Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: A prospective clinical trial by the German 5-FU Toxicity Study Group
-
Schwab M, Zanger UM, Marx C, et al; German 5-FU Toxicity Study Group. Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group. J Clin Oncol. 2008;26(13):2131-2138.
-
(2008)
J Clin Oncol
, vol.26
, Issue.13
, pp. 2131-2138
-
-
Schwab, M.1
Zanger, U.M.2
Marx, C.3
-
12
-
-
0029973215
-
Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity
-
Wei XX, McLeod HL, McMurrough J, Gonzalez FJ, Fernandezsalguero P. Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity. J Clin Invest. 1996;98(3):610-615.
-
(1996)
J Clin Invest
, vol.98
, Issue.3
, pp. 610-615
-
-
Wei, X.X.1
McLeod, H.L.2
McMurrough, J.3
Gonzalez, F.J.4
Fernandezsalguero, P.5
-
13
-
-
0036303541
-
Profound dihydropyrimidine dehydrogenase deficiency resulting from a novel compound heterozygote genotype
-
Johnson MR, Wang K, Diasio RB. Profound dihydropyrimidine dehydrogenase deficiency resulting from a novel compound heterozygote genotype. Clin Can Res. 2002;8(3):768-774.
-
(2002)
Clin Can Res
, vol.8
, Issue.3
, pp. 768-774
-
-
Johnson, M.R.1
Wang, K.2
Diasio, R.B.3
-
14
-
-
0037093447
-
Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three dimensional protein structure
-
van Kuilenburg AB, Dobritzsch D, Meinsma R, et al. Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three dimensional protein structure. Biochem J. 2002;364(pt 1):157-163.
-
(2002)
Biochem J
, vol.364
, Issue.PART. 1
, pp. 157-163
-
-
Van Kuilenburg, A.B.1
Dobritzsch, D.2
Meinsma, R.3
-
15
-
-
84879413456
-
A DPYD variant (Y186C) in individuals of African ancestry is associated with reduced DPD enzyme activity
-
Offer SM, Lee AM, Mattison LK, Fossum C, Wegner NJ, Diasio RB. A DPYD variant (Y186C) in individuals of African ancestry is associated with reduced DPD enzyme activity. Clin Pharmacol Ther. 2013;94(1):158-166.
-
(2013)
Clin Pharmacol Ther
, vol.94
, Issue.1
, pp. 158-166
-
-
Offer, S.M.1
Lee, A.M.2
Mattison, L.K.3
Fossum, C.4
Wegner, N.J.5
Diasio, R.B.6
-
16
-
-
33749350447
-
Increased prevalence of dihydropyrimidine dehydrogenase deficiency in African-Americans compared with Caucasians
-
Mattison LK, Fourie J, Desmond RA, Modak A, Saif MW, Diasio RB. Increased prevalence of dihydropyrimidine dehydrogenase deficiency in African-Americans compared with Caucasians. Clin Cancer Res. 2006;12(18):5491-5495.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.18
, pp. 5491-5495
-
-
Mattison, L.K.1
Fourie, J.2
Desmond, R.A.3
Modak, A.4
Saif, M.W.5
Diasio, R.B.6
-
17
-
-
0033813297
-
Evaluation of dihydropyrimidine dehydrogenase activity in South-west Asian, Kenyan and Ghanaian populations
-
Morsman JM, Sludden J, Ameyaw MM, et al. Evaluation of dihydropyrimidine dehydrogenase activity in South-west Asian, Kenyan and Ghanaian populations. Br J Clin Pharmacol. 2000; 50(3):269-272.
-
(2000)
Br J Clin Pharmacol
, vol.50
, Issue.3
, pp. 269-272
-
-
Morsman, J.M.1
Sludden, J.2
Ameyaw, M.M.3
-
18
-
-
0036629198
-
A highthroughput denaturing high-performance liquid chromatography method for the identification of variant alleles associated with dihydropyrimidine dehydrogenase deficiency
-
Ezzeldin H, Okamoto Y, Johnson MR, Diasio RB. A highthroughput denaturing high-performance liquid chromatography method for the identification of variant alleles associated with dihydropyrimidine dehydrogenase deficiency. Ann Biochem. 2000;306(1):63-73.
-
(2000)
Ann Biochem
, vol.306
, Issue.1
, pp. 63-73
-
-
Ezzeldin, H.1
Okamoto, Y.2
Johnson, M.R.3
Diasio, R.B.4
-
19
-
-
5644228858
-
Simultaneous detection of variable number tandem repeats, single nucleotide polymorphisms, and allelic imbalance in the thymidylate synthase gene enhancer region using denaturing high performance liquid chromatography
-
Ezzeldin H, Hoffmayer C, Soong R, et al. Simultaneous detection of variable number tandem repeats, single nucleotide polymorphisms, and allelic imbalance in the thymidylate synthase gene enhancer region using denaturing high performance liquid chromatography. Ann Biochem. 2004;334(2):276-283.
-
(2004)
Ann Biochem
, vol.334
, Issue.2
, pp. 276-283
-
-
Ezzeldin, H.1
Hoffmayer, C.2
Soong, R.3
-
20
-
-
34548706595
-
G>C SNP of thymidylate synthase with respect to colorectal cancer
-
Gusella M, Padrini R. G>C SNP of thymidylate synthase with respect to colorectal cancer. Pharmacogenomics. 2007;8(8): 985-996.
-
(2007)
Pharmacogenomics
, vol.8
, Issue.8
, pp. 985-996
-
-
Gusella, M.1
Padrini, R.2
-
21
-
-
8344245563
-
Thymidylate synthase expression in normal colonic mucosa: A predictive marker of toxicity in colorectal cancer patients receiving 5-fluorouracil-based adjuvant chemotherapy
-
Santini D, Vincenzi B, Perrone G, et al. Thymidylate synthase expression in normal colonic mucosa: a predictive marker of toxicity in colorectal cancer patients receiving 5-fluorouracil-based adjuvant chemotherapy. Oncology. 2004;67(2):135-142.
-
(2004)
Oncology
, vol.67
, Issue.2
, pp. 135-142
-
-
Santini, D.1
Vincenzi, B.2
Perrone, G.3
-
22
-
-
0035750549
-
Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
-
Pullarkat ST, Stoehlmacher J, Ghaderi V, et al. Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J. 2001; 1(1):65-70.
-
(2001)
Pharmacogenomics J
, vol.1
, Issue.1
, pp. 65-70
-
-
Pullarkat, S.T.1
Stoehlmacher, J.2
Ghaderi, V.3
-
23
-
-
4444339951
-
Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy
-
Lecomte T, Ferraz JM, Zinzindohoué F, et al. Thymidylate synthase gene polymorphism predicts toxicity in colorectal cancer patients receiving 5-fluorouracil-based chemotherapy. Clin Cancer Res. 2004;10(17):5880-5888.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.17
, pp. 5880-5888
-
-
Lecomte, T.1
Ferraz, J.M.2
Zinzindohoué, F.3
-
24
-
-
84877258895
-
Genetic polymorphisms of ERCC1-118, XRCC1-399 and GSTP1-105 are associated with the clinical outcome of gastric cancer patients receiving oxaliplatin-based adjuvant chemotherapy
-
Liu YP, Ling Y, Qi QF, et al. Genetic polymorphisms of ERCC1-118, XRCC1-399 and GSTP1-105 are associated with the clinical outcome of gastric cancer patients receiving oxaliplatin-based adjuvant chemotherapy. Mol Med Rep. 2013;7(6):1904-1911.
-
(2013)
Mol Med Rep
, vol.7
, Issue.6
, pp. 1904-1911
-
-
Liu, Y.P.1
Ling, Y.2
Qi, Q.F.3
-
25
-
-
77954358129
-
Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: Results from North American Gastrointestinal Intergroup Trial N9741
-
McLeod HL, Sargent DJ, Marsh S, et al. Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: results from North American Gastrointestinal Intergroup Trial N9741. J Clin Oncol. 2010; 28(20):3227-3233.
-
(2010)
J Clin Oncol
, vol.28
, Issue.20
, pp. 3227-3233
-
-
McLeod, H.L.1
Sargent, D.J.2
Marsh, S.3
-
26
-
-
75649126926
-
Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma
-
Chen YC, Tzeng CH, Chen PM, et al. Influence of GSTP1 I105V polymorphism on cumulative neuropathy and outcome of FOLFOX-4 treatment in Asian patients with colorectal carcinoma. Cancer Sci. 2010;101(2):530-535.
-
(2010)
Cancer Sci
, vol.101
, Issue.2
, pp. 530-535
-
-
Chen, Y.C.1
Tzeng, C.H.2
Chen, P.M.3
-
27
-
-
77956398850
-
Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05
-
Boige V, Mendiboure J, Pignon JP, et al. Pharmacogenetic assessment of toxicity and outcome in patients with metastatic colorectal cancer treated with LV5FU2, FOLFOX, and FOLFIRI: FFCD 2000-05. J Clin Oncol. 2010;28(15): 2556-2564.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15
, pp. 2556-2564
-
-
Boige, V.1
Mendiboure, J.2
Pignon, J.P.3
-
28
-
-
73949096486
-
Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: The FOCUS trial
-
Braun MS, Richman SD, Thompson L, et al. Association of molecular markers with toxicity outcomes in a randomized trial of chemotherapy for advanced colorectal cancer: the FOCUS trial. J Clin Oncol. 2009;27(33):5519-5528.
-
(2009)
J Clin Oncol
, vol.27
, Issue.33
, pp. 5519-5528
-
-
Braun, M.S.1
Richman, S.D.2
Thompson, L.3
|