Metabolomic approach for discrimination of processed ginseng genus (Panax ginseng and Panax quinquefolius) using UPLC-QTOF MS

Journal of Ginseng Research

Volumn 38, Issue 1, 2014, Pages 59-65

  Park, Hee Won ^a   In, Gyo ^a   Kim, Jeong Han ^b   Cho, Byung Goo ^a   Han, Gyeong Ho ^a   Chang, Il Moo ^a  

^a Korea Ginseng Corporation   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Discrimination; Metabolomics; Panax ginseng; Panax quinquefolius; UPLC QTOF MS

Indexed keywords

BIOLOGICAL MARKER; DRUG METABOLITE; GINSENOSIDE; GINSENOSIDE RF; PSEUDOGINSENOSIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DISCRIMINATION; DRUG SCREENING; GINSENG; HERBAL MEDICINE; METABOLITE; METABOLOMICS; NONHUMAN; PANAX QUINQUEFOLIUS; THERAPY EFFECT; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84893016096     PISSN: 12268453     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jgr.2013.11.011     Document Type: Article

References (28)

1. Soldati F. Panax ginseng; standardization and biological activity. In: Cutler SJ, Cutler HG, editors. Biologically active natural products. New York: CRC Press; 2000. pp. 209-32.
2. Baeg IH, So SH. The world ginseng market and the ginseng (Korea). J Ginseng Res 2013;37:1-7.
3. Chan TWD, But PPH, Cheng SW, Kwok IMY, Lau FW, Xu HX. Differentiation and authentication of Panax ginseng, Panax quinquefolius, and ginseng products by using HPLC/MS. Anal Chem 2000;72:1281-7.
4. Leung Kelvin SY, Chan K, Bensoussan A, Munroe MJ. Application of atmospheric pressure chemical ionization mass spectrometry in the identification and differentiation of Panax species. Phytochem Anal 2007;18:146-50.
5. Li L, Luo GA, Liang QL, Hu P, Wang YM. Rapid qualitative and quantitative analyses of Asian ginseng in adulterated American ginseng preparations by UPLC/Q-TOF-MS. J Pharm Biomed Anal 2010;52:66-72.
6. Lai YH, So PK, Lo Samual CL, Ng Eddy WY, Poon Terence CW, Yao Z-P. Rapid differentiation of Panax ginseng and Panax quinquefolius by matrixassisted laser desorption/ionization mass spectrometry. Anal Chim Acta 2012;753:73-81.
7. Shyur LF, Yang NS. Metabolomics for phytomedicine research and drug development. Curr Opin Chem Biol 2008;12:66-71.
8. Wishart DS. Metabolomics; application to food science and nutrition research. Trends Food Sci Technol 2008;19:482-93.
9. Cevallos JM, Corcuera JIR-D, Etxeberria E, Danyluk MD, Rodrick GE. Metabolomics in food science: a review. Trends Food Sci Technol 2009;20:557-66.
10. Bictash M, Ebbels TM, Chan Q, Loo RL, Yap Ivan KS, Brown IJ, Iorio MD, Daviglus ML, Holmes E, Stamler J, et al. Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology. J Clin Epidemiol 2010;63:970-9.
11. Madsen R, Lundstedt T, Trygg J. Chemometrics in metabolomicsda review in human disease diagnosis. Anal Chim Acta 2010;659:223-33.
12. Putri SP, Nakayama Y, Matsuda F, Uchikata T, Kobayashi S, Matsubara A, Fukusaki E. Current metabolomics: practical applications. J Biosci Bioeng 2013;115:579-89.
13. Kim HK, Choi YH, Verpoorte R. NMR-based plant metabolomics: where do we stand, where do we go? Trends Biotechnol 2011;29:267-75.
14. Xiao JF, Zhou B, Ressom HW. Metabolite identification and quantitation in LCMS/ MS-based metabolomics. Trends Anal Chem 2012;32:1-14.
15. Dan M, Su M, Gao X, Zhao T, Zhao A, Xie G, Qiu Y, Zhou M, Liu Z, Jia W. Metabolite profiling of Panax notoginseng using UPLC-ESI-MS. Phytochemistry 2008;69:2237-44.
16. Xie G, Plumb R, Su M, Xu Z, Zhao A, Qiu M, Liu Z, Jia W. Ultra-performance LC/ TOF MS analysis of medicinal Panax herbs for metabolomic research. J Sep Sci 2008;31:1015-26.
17. Zhang HM, Li SL, Zhang H, Wang Y, Zhao ZL, Chen SL, Xu HX. Holistic quality evaluation of commercial white and red ginseng using a UPLC-QTOF-MS/MSbased metabolomics approach. J Pharm Biomed 2012;62:258-73.
18. Shin YS, Bang KH, In DS, Kim OT, Hyun DY, Ahn IO, Ku BC, Kim SW, Seong NS, Cha SW, et al. Fingerprinting analysis of fresh ginseng roots of different ages using 1H-NMR spectroscopy and principal components analysis. Arch Pharm Res 2007;30:1625-8.
19. Kang JH, Lee SY, Kang SM, Kwon HN, Park JH, Kwon SW, Park SH. NMR-based metabolomics approach for the differentiation of ginseng (Panax ginseng) roots from different origins. Arch Pharm Res 2008;31:330-6.
20. Lin WN, Lu HY, Lee MS, Yang SY, Chen HJ, Chang YS, Chang WT. Evaluation of the cultivation age of dried ginseng radix and its commercial products by using 1H-NMR fingerprint analysis. Am J Chinese Med 2010;38:205-18.
21. Kim NH, Kim KO, Choi BY, Lee DH, Shin YS, Bang KH, Cha SW, Lee JW, Choi HK, Jang DS, et al. Metabolomic approach for age discrimination of Panax ginseng using UPLC-Q-Rof MS. J Agric Food Chem 2011;59:10435-41.
22. Kim NH, Kim KO, Lee DH, Shin YS, Bang KH, Cha SW, Lee JW, Choi HK, Hwang BY, Lee DH. Nontargeted metabolomics approach for age differentiation and structure interpretation of age-dependent key constituents in hairy roots of Panax ginseng. J Nat Prod 2012;75:1777-84.
23. Yang SO, Shin YS, Hyun SH, Cho SY, Bang KH, Lee DH, Choi SP, Choi HK. NMRbased metabolic profiling and differentiation of ginseng roots according to cultivation ages. J Pharmaceut Biomed 2012;58:19-26.
24. Song HH, Kim DY, Woo S, Lee HK, Oh SR. An approach for simultaneous determination for geographical origins of Korean Panax ginseng by UPLCQTOF/ MS coupled with OPLS-DA models. J Ginseng Res 2013;37:341-8.
25. In G, Ahn NG, Bae BS, Han ST, Noh KB, Kim CS. New method for simultaneous quantification of 12 ginsenosides in red ginseng powder and extract: in-house method validation. J Ginseng Res 2012;36:205-10.
26. Park HW, In G, Lee MW, Kim SY, Kim KT, Cho BG, Han GH, Chang IM. Simultaneous determination of 30 ginsenosides in Panax ginseng preparations using ultra performance liquid chromatography. J Ginseng Res 2013;37:457-67.
27. Christensen LP. Ginsenoside: chemistry, biosynthesis, analysis and potential health effects. Adv Food Nutr Res 2008;55:1-99.
28. Park JD. Recent studies on the chemical constituents of Korean ginseng. Korean J Ginseng Sci 1996;20:389-415.