Tumour supressor secreted frizzled related protein 1 regulates p53-mediated apoptosis

Cell Biology International

Volumn 38, Issue 1, 2014, Pages 124-130

  Gauger, Kelly J ^a,b   Schneider, Sallie S ^a,b  

^a BAYSTATE MEDICAL CENTER   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Apoptosis; Mammary gland; P53; SFRP1

Indexed keywords

BIM PROTEIN; CASPASE 3; CYCLIN DEPENDENT KINASE INHIBITOR; DNA; MESSENGER RNA; PROTEIN BAX; PROTEIN P53; PUMA PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1;

ANIMAL CELL; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; DNA DAMAGE; DNA FRAGMENTATION; FEMALE; GAMMA IRRADIATION; GENE EXPRESSION REGULATION; GENE LOSS; GENE TARGETING; MAMMARY GLAND; MOUSE; NONHUMAN; PROTEIN FUNCTION;

MUS;

APOPTOSIS; MAMMARY GLAND; P53; SFRP1;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DOWN-REGULATION; FEMALE; MAMMARY GLANDS, ANIMAL; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PROTEINS; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH PROTEINS;

EID: 84892975552     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1002/cbin.10176     Document Type: Article

References (24)

1. Bodine PV, Billiard J, Moran RA, Ponce-de-Leon H, McLarney S, Mangine A, Scrimo MJ, Bhat RA, Stauffer B, Green J, Stein GS, Lian JB, Komm BS (2005) The Wnt antagonist secreted frizzledrelated protein-1 controls osteoblast and osteocyte apoptosis. J Cell Biochem 96(6): 1212-30.
2. Cooper SJ, von Roemeling CA, Kang KH, Marlow LA, Grebe SK, Menefee ME, Tun HW, Colon-Otero G, Perez EA, Copland JA (2012) Reexpression of tumor suppressor, sFRP1, leads to antitumor synergy of combined HDAC and methyltransferase inhibitors in chemoresistant cancers. Mol Cancer Ther 11(10): 2105-15.
3. Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, Kawamura MJ, Wicha MS (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17(10): 1253-70.
4. Dumont N, Crawford YG, Sigaroudinia M, Nagrani SS, Wilson MB, Buehring GC, Turashvili G, Aparicio S, Gauthier ML, Fordyce CA, McDermott KM, Tlsty TD (2009) Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy. Breast Cancer Res 11(6): R87.
5. Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, Jia M, Shepherd R, Leung K, Menzies A, Teague JW, Campbell PJ, Stratton MR, Futreal PA (2011) COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucl Acids Res 39(Database issue): D945-50.
6. Gartel AL, Tyner AL (1999) Transcriptional regulation of the p21 ((WAF1/CIP1)) gene. Exp Cell Res 246: 280-9.
7. Gauger KJ, Hugh JM, Troester MA, Schneider SS (2009) Downregulation of sfrp1 in a mammary epithelial cell line promotes the development of a cd44high/cd24low population which is invasive and resistant to anoikis. Cancer Cell Int 9: 11.
8. Gauger KJ, Shimono A, Crisi GM, Schneider SS (2012) Loss of SFRP1 promotes ductal branching in the murine mammary gland. BMC Dev Biol 12: 25.
9. Hartwell LH, Kastan MB (1994) Cell cycle control and cancer. Science (New York, NY) 266(5192): 1821-8.
10. Horn HF, Vousden KH (2007) Coping with stress: multiple ways to activate p53. Oncogene 26(9): 1306-16.
11. Jemal A, Siegel R, Xu J,Ward E Cancer statistics, 2010. CA Cancer J Clin 60(5): 277-300.
12. Jiang GX, LiuW, Cui YF, Zhong XY, Tai S,Wang ZD, Shi YG, Li CL, Zhao SY (2010) Reconstitution of secreted frizzled-related protein 1 suppresses tumor growth and lung metastasis in an orthotopic model of hepatocellular carcinoma. Dig Dis Sci 55 (10): 2838-43.
13. Klopocki E, Kristiansen G, Wild PJ, Klaman I, Castanos-Velez E, Singer G, Stohr R, Simon R, Sauter G, Leibiger H, Essers L, Weber B, Hermann K, Rosenthal A, Hartmann A, Dahl E (2004) Loss of SFRP1 is associated with breast cancer progression and poor prognosis in early stage tumors. Int J Oncol 25(3): 641-9.
14. Kuperwasser C, Hurlbut GD, Kittrell FS, Dickinson ES, Laucirica R, Medina D, Naber SP, Jerry DJ (2000) Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome. Am J Pathol 157(6): 2151-9.
15. Lacher MD, Siegenthaler A, Jager R, Yan X, Hett S, Xuan L, Saurer S, Lareu RR, Dharmarajan AM, Friis R (2003) Role of DDC-4/sFRP-4, a secreted frizzled-related protein, at the onset of apoptosis in mammary involution. Cell Death Differ 10(5): 528-38.
16. Lo PK, Mehrotra J, D'Costa A, Fackler MJ, Garrett-Mayer E, Argani P, Sukumar S (2006) Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. Cancer Biol Therapy 5(3): 281-6.
17. Oltvai ZN, Milliman CL, Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74(4): 609-19.
18. Reginato MJ, Mills KR, Becker EB, Lynch DK, Bonni A, Muthuswamy SK, Brugge JS (2005) Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. Mol Cell Biol 25(11): 4591-601.
19. Roman-Gomez J, Cordeu L, Agirre X, Jimenez-Velasco A, San Jose-Eneriz E, Garate L, Calasanz MJ, Heiniger A, Torres A, Prosper F (2006) Epigenetic regulation ofWNTsignaling pathway in acute lymphoblastic leukemia. Blood 109(8): 3462-9.
20. Saran U, Arfuso F, Zeps N, Dharmarajan A (2010) Secreted frizzled-related protein 4 expression is positively associated with responsiveness to cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers. BMC Cell Biol 13: 25.
21. Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, Bell G, GuoW, Rubin J, Richardson AL,Weinberg RA (2011) Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 145(6): 926-40.
22. Schmitt CA, Fridman JS, Yang M, Baranov E, Hoffman RM, Lowe SW (2002) Dissecting p53 tumor suppressor functions in vivo. Cancer cell 1(3): 289-98.
23. Seol MB, Bong JJ, Baik M (2005) Expression profiles of apoptosis genes in mammary epithelial cells. Mol Cells 20(1): 97-104.
24. Veeck J, Niederacher D, An H, Klopocki E, Wiesmann F, Betz B, Galm O, Camara O, Durst M, Kristiansen G,Huszka C, Knuchel R, Dahl E (2006) Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis. Oncogene 25(24): 3479-88.