메뉴 건너뛰기




Volumn 8, Issue JAN, 2014, Pages

Negative learning bias is associated with risk aversion in a genetic animal model of depression

Author keywords

Behavior; cLH; Depression; Helplessness; Lateral habenula; Reinforcement learning; Reward; Risk aversion

Indexed keywords

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVERSION; CONDITIONED REFLEX; CONTROLLED STUDY; DEPRESSION; HABENULA; HIGH RISK BEHAVIOR; LEARNED HELPLESSNESS; LEARNING; MALE; NONHUMAN; RAT; REWARD; STIMULUS RESPONSE;

EID: 84892953288     PISSN: 16625161     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnhum.2014.00001     Document Type: Article
Times cited : (9)

References (19)
  • 1
    • 0035955499 scopus 로고    scopus 로고
    • The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress
    • doi: 10.1016/S0006-8993(01)02934-1
    • Amat, J., Sparks, P. D., Matus-Amat, P., Griggs, J., Watkins, L. R., and Maier, S. F. (2001). The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress. Brain Res. 917, 118-126. doi: 10.1016/S0006-8993(01)02934-1
    • (2001) Brain Res , vol.917 , pp. 118-126
    • Amat, J.1    Sparks, P.D.2    Matus-Amat, P.3    Griggs, J.4    Watkins, L.R.5    Maier, S.F.6
  • 2
    • 0023828835 scopus 로고
    • Interictal changes in behavior and cerebral metabolism in the rat: Opioid involvement
    • doi: 10.1016/0014-4886(88)90128-8
    • Caldecott-Hazard, S. (1988). Interictal changes in behavior and cerebral metabolism in the rat: opioid involvement. Exp. Neurol. 99, 73-83. doi: 10.1016/0014-4886(88)90128-8
    • (1988) Exp. Neurol , vol.99 , pp. 73-83
    • Caldecott-Hazard, S.1
  • 4
    • 77249094458 scopus 로고    scopus 로고
    • Stress triggers anhedonia in rats bred for learned helplessness
    • doi: 10.1016/j.bbr.2010.01.042
    • Enkel, T., Spanagel, R., Vollmayr, B., and Schneider, M. (2010b). Stress triggers anhedonia in rats bred for learned helplessness. Behav. Brain Res. 209, 183-186. doi: 10.1016/j.bbr.2010.01.042
    • (2010) Behav. Brain Res , vol.209 , pp. 183-186
    • Enkel, T.1    Spanagel, R.2    Vollmayr, B.3    Schneider, M.4
  • 5
    • 5044228631 scopus 로고    scopus 로고
    • Discovering endophenotypes for major depression
    • doi: 10.1038/sj.npp.1300506
    • Hasler, G., Drevets, W. C., Manji, H. K., and Charney, D. S. (2004). Discovering endophenotypes for major depression. Neuropsychopharmacology 29, 1765-1781. doi: 10.1038/sj.npp.1300506
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1765-1781
    • Hasler, G.1    Drevets, W.C.2    Manji, H.K.3    Charney, D.S.4
  • 6
    • 58149328473 scopus 로고    scopus 로고
    • Habenula: Crossroad between the basal ganglia and the limbic system
    • doi: 10.1523/JNEUROSCI.3463-08.2008
    • Hikosaka, O., Sesack, S. R., Lecourtier, L., and Shepard, P. D. (2008). Habenula: crossroad between the basal ganglia and the limbic system. J. Neurosci. 28, 11825-11829. doi: 10.1523/JNEUROSCI.3463-08.2008
    • (2008) J. Neurosci , vol.28 , pp. 11825-11829
    • Hikosaka, O.1    Sesack, S.R.2    Lecourtier, L.3    Shepard, P.D.4
  • 7
    • 34347324115 scopus 로고    scopus 로고
    • Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism
    • doi: 10.1523/JNEUROSCI.0958-07.2007
    • Ji, H., and Shepard, P. D. (2007). Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism. J. Neurosci. 27, 6923-6930. doi: 10.1523/JNEUROSCI.0958-07.2007
    • (2007) J. Neurosci , vol.27 , pp. 6923-6930
    • Ji, H.1    Shepard, P.D.2
  • 8
    • 0035881796 scopus 로고    scopus 로고
    • Genetic predisposition and the development of posttraumatic stress disorder in an animal model
    • doi: 10.1016/S0006-3223(01)01071-X
    • King, J. A., Abend, S., and Edwards, E. (2001). Genetic predisposition and the development of posttraumatic stress disorder in an animal model. Biol. Psychiatry 50, 231-237. doi: 10.1016/S0006-3223(01)01071-X
    • (2001) Biol. Psychiatry , vol.50 , pp. 231-237
    • King, J.A.1    Abend, S.2    Edwards, E.3
  • 9
    • 0027251003 scopus 로고
    • Differential development of the stress response in congenital learned helplessness
    • doi: 10.1016/0736-5748(93)90017-8
    • King, J. A., Campbell, D., and Edwards, E. (1993). Differential development of the stress response in congenital learned helplessness. Int. J. Dev. Neurosci. 11, 435-442. doi: 10.1016/0736-5748(93)90017-8
    • (1993) Int. J. Dev. Neurosci , vol.11 , pp. 435-442
    • King, J.A.1    Campbell, D.2    Edwards, E.3
  • 10
    • 79952129505 scopus 로고    scopus 로고
    • Synaptic potentiation onto habenula neurons in the learned helplessness model of depression
    • doi: 10.1038/nature09742
    • Li, B., Piriz, J., Mirrione, M., Chung, C., Proulx, C. D., Schulz, D., et al. (2011). Synaptic potentiation onto habenula neurons in the learned helplessness model of depression. Nature 470, 535-539. doi: 10.1038/nature09742
    • (2011) Nature , vol.470 , pp. 535-539
    • Li, B.1    Piriz, J.2    Mirrione, M.3    Chung, C.4    Proulx, C.D.5    Schulz, D.6
  • 11
    • 84883122151 scopus 로고    scopus 로고
    • betaCaMKII in lateral habenula mediates core symptoms of depression
    • doi: 10.1126/science.1240729
    • Li, K., Zhou, T., Liao, L., Yang, Z., Wong, C., Henn, F., et al. (2013). betaCaMKII in lateral habenula mediates core symptoms of depression. Science 341, 1016-1020. doi: 10.1126/science.1240729
    • (2013) Science , vol.341 , pp. 1016-1020
    • Li, K.1    Zhou, T.2    Liao, L.3    Yang, Z.4    Wong, C.5    Henn, F.6
  • 12
    • 84995186518 scopus 로고
    • Portfolio selection
    • doi: 10.1111/j.1540-6261.1952.tb01525.x
    • Markowitz, H. (1952). Portfolio selection. J. Financ. 7, 77-91. doi: 10.1111/j.1540-6261.1952.tb01525.x
    • (1952) J. Financ , vol.7 , pp. 77-91
    • Markowitz, H.1
  • 13
    • 34347343926 scopus 로고    scopus 로고
    • Lateral habenula as a source of negative reward signals in dopamine neurons
    • doi: 10.1038/nature05860
    • Matsumoto, M., and Hikosaka, O. (2007). Lateral habenula as a source of negative reward signals in dopamine neurons. Nature 447, 1111-1115. doi: 10.1038/nature05860
    • (2007) Nature , vol.447 , pp. 1111-1115
    • Matsumoto, M.1    Hikosaka, O.2
  • 14
    • 33746898593 scopus 로고    scopus 로고
    • Encoding of time-discounted rewards in orbitofrontal cortex is independent of value representation
    • doi: 10.1016/j.neuron.2006.06.027
    • Roesch, M. R., Taylor, A. R., and Schoenbaum, G. (2006). Encoding of time-discounted rewards in orbitofrontal cortex is independent of value representation. Neuron 51, 509-520. doi: 10.1016/j.neuron.2006.06.027
    • (2006) Neuron , vol.51 , pp. 509-520
    • Roesch, M.R.1    Taylor, A.R.2    Schoenbaum, G.3
  • 15
    • 84856098183 scopus 로고    scopus 로고
    • Cognitive mechanisms of treatment in depression
    • doi: 10.1038/npp.2011.183
    • Roiser, J. P., Elliott, R., and Sahakian, B. J. (2012). Cognitive mechanisms of treatment in depression. Neuropsychopharmacology 37, 117-136. doi: 10.1038/npp.2011.183
    • (2012) Neuropsychopharmacology , vol.37 , pp. 117-136
    • Roiser, J.P.1    Elliott, R.2    Sahakian, B.J.3
  • 16
    • 21744435555 scopus 로고    scopus 로고
    • Reduced sensitivity to sucrose in rats bred for helplessness: A study using the matching law
    • doi: 10.1097/01.fbp.0000171772.61669.6f
    • Sanchis-Segura, C., Spanagel, R., Henn, F. A., and Vollmayr, B. (2005). Reduced sensitivity to sucrose in rats bred for helplessness: a study using the matching law. Behav. Pharmacol. 16, 267-270. doi: 10.1097/01.fbp.0000171772.61669.6f
    • (2005) Behav. Pharmacol , vol.16 , pp. 267-270
    • Sanchis-Segura, C.1    Spanagel, R.2    Henn, F.A.3    Vollmayr, B.4
  • 17
    • 25144502804 scopus 로고    scopus 로고
    • Behavioral characteristics of rats predisposed to learned helplessness: Reduced reward sensitivity, increased novelty seeking, and persistent fear memories
    • doi: 10.1016/j.bbr.2005.06.016
    • Shumake, J., Barrett, D., and Gonzalez-Lima, F. (2005). Behavioral characteristics of rats predisposed to learned helplessness: reduced reward sensitivity, increased novelty seeking, and persistent fear memories. Behav. Brain Res. 164, 222-230. doi: 10.1016/j.bbr.2005.06.016
    • (2005) Behav. Brain Res , vol.164 , pp. 222-230
    • Shumake, J.1    Barrett, D.2    Gonzalez-Lima, F.3
  • 18
    • 0037435977 scopus 로고    scopus 로고
    • Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior
    • doi: 10.1016/S0006-8993(02)04048-9
    • Shumake, J., Edwards, E., and Gonzalez-Lima, F. (2003). Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior. Brain Res. 963, 274-281. doi: 10.1016/S0006-8993(02)04048-9
    • (2003) Brain Res , vol.963 , pp. 274-281
    • Shumake, J.1    Edwards, E.2    Gonzalez-Lima, F.3
  • 19
    • 1642337214 scopus 로고    scopus 로고
    • Rats with congenital learned helplessness respond less to sucrose but show no deficits in activity or learning
    • doi: 10.1016/S0166-4328(03)00259-6
    • Vollmayr, B., Bachteler, D., Vengeliene, V., Gass, P., Spanagel, R., and Henn, F. (2004). Rats with congenital learned helplessness respond less to sucrose but show no deficits in activity or learning. Behav. Brain Res. 150, 217-221. doi: 10.1016/S0166-4328(03)00259-6
    • (2004) Behav. Brain Res , vol.150 , pp. 217-221
    • Vollmayr, B.1    Bachteler, D.2    Vengeliene, V.3    Gass, P.4    Spanagel, R.5    Henn, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.