A detailed analysis of treatment delay from the onset of symptoms in early rheumatoid arthritis patients

Scandinavian Journal of Rheumatology

Volumn 43, Issue 1, 2014, Pages 1-8

  De Cock, D ^a   Meyfroidt, S ^a   Joly, J ^b   Van Der Elst, K ^a,c   Westhovens, R ^a,b   Verschueren, P ^a,b  

^a Division of Rheumatology UZ Leuven   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE MODIFYING ANTIRHEUMATIC DRUG;

ADULT; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ACTIVITY; DISEASE SEVERITY; FEMALE; FOLLOW UP; GENERAL HOSPITAL; GENERAL PRACTITIONER; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORNING STIFFNESS; MULTICENTER STUDY; PATIENT CODING; PRIORITY JOURNAL; PRIVATE PRACTICE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RHEUMATOID ARTHRITIS; RHEUMATOLOGY; THERAPY DELAY; TREATMENT DURATION; TREATMENT RESPONSE;

ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; MALE; MIDDLE AGED; REFERRAL AND CONSULTATION; RHEUMATOLOGY; TIME FACTORS; TREATMENT OUTCOME;

EID: 84892951908     PISSN: 03009742     EISSN: 15027732     Source Type: Journal    
DOI: 10.3109/03009742.2013.805242     Document Type: Article

References (44)

1. van der Heijde DM. Joint erosions and patients with early rheumatoid arthritis. Br J Rheumatol 1995;34(Suppl 2):74-8.
2. Fuchs HA, Kaye JJ, Callahan LF, Nance EP, Pincus T. Evidence of significant radiographic damage in rheumatoid arthritis within the first 2 years of disease. J Rheumatol 1989;16:585-91. (Pubitemid 19154397)
3. Buckland-Wright JC, Clarke GS, Chikanza IC, Grahame R. Quantitative microfocal radiography detects changes in erosion area in patients with early rheumatoid arthritis treated with myocrisine. J Rheumatol 1993;20:243-7. (Pubitemid 23066032)
4. Egsmose C, Lund B, Borg G, Pettersson H, Berg E, Brodin U, et al. Patients with rheumatoid arthritis benefit from early 2nd line therapy: 5 year followup of a prospective double blind placebo controlled study. J Rheumatol 1995;22:2208-13.
5. O'Dell JR, Paulsen G, Haire CE, Blakely K, Palmer W, Wees S, et al. Treatment of early seropositive rheumatoid arthritis with minocycline: four-year followup of a double-blind, placebocontrolled trial. Arthritis Rheum 1999;42:1691-5. (Pubitemid 30263638)
6. Tsakonas E, Fitzgerald AA, Fitzcharles MA, Cividino A, Thorne JC, M'Seffar A, et al. Consequences of delayed therapy with second-line agents in rheumatoid arthritis: a 3 year followup on the hydroxychloroquine in early rheumatoid arthritis (HERA) study. J Rheumatol 2000;27:623-9. (Pubitemid 30151337)
7. Anderson JJ, Wells G, Verhoeven AC, Felson DT. Factors predicting response to treatment in rheumatoid arthritis: the importance of disease duration. Arthritis Rheum 2000;43:22-9. (Pubitemid 30368209)
8. Lard LR, Visser H, Speyer I, vander Horst-Bruinsma IE, Zwinderman AH, Breedveld FC, et al. Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies. Am J Med 2001;111:446-51. (Pubitemid 33016415)
9. Mottonen T, Hannonen P, Korpela M, Nissila M, Kautiainen H, Ilonen J, et al. Delay to institution of therapy and induction of remission using single-drug or combination-disease-modifying antirheumatic drug therapy in early rheumatoid arthritis. Arthritis Rheum 2002;46:894-8. (Pubitemid 34303799)
10. Nell VP, Machold KP, Eberl G, Stamm TA, Uffmann M, Smolen JS. Benefit of very early referral and very early therapy with diseasemodifying anti-rheumatic drugs in patients with early rheumatoid arthritis. Rheumatology (Oxford) 2004;43:906-14. (Pubitemid 38996967)
11. Kyburz D, Gabay C, Michel BA, Finckh A. The long-term impact of early treatment of rheumatoid arthritis on radiographic progression: a population-based cohort study. Rheumatology (Oxford) 2011;50:1106-10.
12. Finckh A, Liang MH, van Herckenrode CM, de Pablo P. Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: a meta-analysis. Arthritis Rheum 2006;55:864-72. (Pubitemid 44917458)
13. van der Linden MP, le Cessie S, Raza K, van der Woude D, Knevel R, Huizinga TW, et al. Long-term impact of delay in assessment of patients with early arthritis. Arthritis Rheum 2010;62:3537-46.
14. Bosello S, Fedele AL, Peluso G, Gremese E, Tolusso B, Ferraccioli G. Very early rheumatoid arthritis is the major predictor of major outcomes: clinical ACR remission and radiographic nonprogression. Ann Rheum Dis 2011;70:1292-5.
15. Bykerk VP, Keystone EC. What are the goals and principles of management in the early treatment of rheumatoid arthritis? Best Pract Res Clin Rheumatol 2005;19:147-61. (Pubitemid 40003946)
16. Raza K, Buckley CE, Salmon M, Buckley CD. Treating very early rheumatoid arthritis. Best Pract Res Clin Rheumatol 2006;20:849-63. (Pubitemid 44382383)
17. Raza K. The Michael Mason prize: early rheumatoid arthritis - the window narrows. Rheumatology (Oxford) 2010;49:406-10.
18. Smolen JS, Landewe R, Breedveld FC, Dougados M, Emery P, Gaujoux-Viala C, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis 2010; 69:964-75.
19. Deighton C, O'Mahony R, Tosh J, Turner C, Rudolf M. Management of rheumatoid arthritis: summary of NICE guidance. Br Med J 2009;338:b702.
20. Singh JA, Furst DE, Bharat A, Curtis JR, Kavanaugh AF, Kremer JM, et al. 2012 update of the 2008 American College of Rheumatology recommendations for the use of disease-modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis. Arthritis Care Res (Hoboken) 2012;64:625-39.
21. Irvine S, Munro R, Porter D. Early referral, diagnosis, and treatment of rheumatoid arthritis: evidence for changing medical practice. Ann Rheum Dis 1999;58:510-13. (Pubitemid 29359497)
22. Gray M, Nuki J. Audit of delay between symptom onset and commencement of disease modifying anti-rheumatic drugs (DMARDs) in patients with newly diagnosed rheumatoid arthritis referred to a hospital rheumatology unit. Rheumatology (Oxford) 2001;40(Suppl 1):60.
23. Jeyaratnam R, Kerr LD, Spiera H, Crane RP, Pugh MT. A comparative analysis of the time taken from onset of symptoms of rheumatoid arthritis to initiation of disease modifying antirheumatic drugs at Mount Sinai Hospital, USA and the Birmingham Heartlands Hospital, UK. Rheumatology (Oxford) 2001;40(Suppl 1):29.
24. Potter T, Mulherin D, Pugh M. Early intervention with diseasemodifying therapy for rheumatoid arthritis: where do the delays occur? Rheumatology (Oxford) 2002;41:953-5; author reply 5.
25. Raza K, Stack R, Kumar K, Filer A, Detert J, Bastian H, et al. Delays in assessment of patients with rheumatoid arthritis: variations across Europe. Ann Rheum Dis 2011;70:1822-5.
26. Rodriguez-Polanco E, Al Snih S, Kuo YF, Millan A, Rodriguez MA. Lag time between onset of symptoms and diagnosis in Venezuelan patients with rheumatoid arthritis. Rheumatol Int 2011;31:657-65.
27. Nanji JA, Choi M, Ferrari R, Lyddell C, Russell AS. Time to consultation and disease-modifying antirheumatic drug treatment of patients with rheumatoid arthritis - Northern Alberta perspective. J Rheumatol 2012;39:707-11.
28. Kumar K, Daley E, Carruthers DM, Situnayake D, Gordon C, Grindulis K, et al. Delay in presentation to primary care physicians is the main reason why patients with rheumatoid arthritis are seen late by rheumatologists. Rheumatology (Oxford) 2007;46:1438-40. (Pubitemid 47317090)
29. Feldman DE, Bernatsky S, Haggerty J, Leffondre K, Tousignant P, Roy Y, et al. Delay in consultation with specialists for persons with suspected new-onset rheumatoid arthritis: a population-based study. Arthritis Rheum 2007;57:1419-25. (Pubitemid 350308839)
30. Sheppard J, Kumar K, Buckley CD, Shaw KL, Raza K. 'I just thought it was normal aches and pains': a qualitative study of decision-making processes in patients with early rheumatoid arthritis. Rheumatology (Oxford) 2008;47:1577-82.
31. Kumar K, Daley E, Khattak F, Buckley CD, Raza K. The influence of ethnicity on the extent of, and reasons underlying, delay in general practitioner consultation in patients with RA. Rheumatology (Oxford) 2010;49:1005-12.
32. Stack RJ, Shaw K, Mallen C, Herron-Marx S, Horne R, Raza K. Delays in help seeking at the onset of the symptoms of rheumatoid arthritis: a systematic synthesis of qualitative literature. Ann Rheum Dis 2012;71:493-7.
33. Felson DT, Meenan RF, Dayno SJ, Gertman P. Referral of musculoskeletal disease patients by family and general practitioners. Arthritis Rheum 1985;28:1156-62. (Pubitemid 16250652)
34. Glazier RH, Dalby DM, Badley EM, Hawker GA, Bell MJ, Buchbinder R, et al. Management of the early and late presentations of rheumatoid arthritis: a survey of Ontario primary care physicians. Can Med Assoc J 1996;155:679-87. (Pubitemid 26336233)
35. Sinclair D, Hull RG. Why do general practitioners request rheumatoid factor? A study of symptoms, requesting patterns and patient outcome. Ann Clin Biochem 2003;40:131-7. (Pubitemid 36359863)
36. Suter LG, Fraenkel L, Holmboe ES. What factors account for referral delays for patients with suspected rheumatoid arthritis? Arthritis Rheum 2006;55:300-5.
37. Lard LR, Huizinga TW, Hazes JM, Vliet Vlieland TP. Delayed referral of female patients with rheumatoid arthritis. J Rheumatol 2001;28:2190-2. (Pubitemid 32947860)
38. Palm O, Purinszky E. Women with early rheumatoid arthritis are referred later than men. Ann Rheum Dis 2005;64:1227-8. (Pubitemid 41113364)
39. Tavares R, Pope JE, Tremblay JL, Thorne C, Bykerk VP, Lazovskis J, et al. Time to disease-modifying antirheumatic drug treatment in rheumatoid arthritis and its predictors: a national, multicenter, retrospective cohort. J Rheumatol 2012;39:2088-97.
40. Jamal S, Alibhai SM, Badley EM, Bombardier C. Time to treatment for new patients with rheumatoid arthritis in a major metropolitan city. J Rheumatol 2011;38:1282-8.
41. Hernandez-Garcia C, Vargas E, Abasolo L, Lajas C, Bellajdell B, Morado IC, et al. Lag time between onset of symptoms and access to rheumatology care and DMARD therapy in a cohort of patients with rheumatoid arthritis. J Rheumatol 2000;27:2323-8.
42. Chan KW, Felson DT, Yood RA, Walker AM. The lag time between onset of symptoms and diagnosis of rheumatoid arthritis. Arthritis Rheum 1994;37:814-20. (Pubitemid 24184530)
43. Fitzgerald A, de Coster C, McMillan S, Naden R, Armstrong F, Barber A, et al. Relative urgency for referral from primary care to rheumatologists: the Priority Referral Score. Arthritis Care Res (Hoboken) 2011;63:231-9.
44. van Nies JA, Brouwer E, van Gaalen FA, Allaart CF, Huizinga TW, Posthumus MD, et al. Improved early identification of arthritis: evaluating the efficacy of Early Arthritis Recognition Clinics. Ann Rheum Dis 2012;0:1-7.