A general strategy for antibody library screening via conversion of transient target binding into permanent reporter deposition

Protein Engineering, Design and Selection

Volumn 27, Issue 2, 2014, Pages 41-47

  Maaß, Alexander ^a   Heiseler, Tim ^a   Maaß, Franziska ^a   Fritz, Janine ^a   Hofmeyer, Thomas ^a   Glotzbach, Bernhard ^a   Becker, Stefan ^b   Kolmar, Harald ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^b Merck Serono GmbH   (Germany)

Author keywords

antibody engineering; catalysed reporter deposition; oxidase; peroxidase; phage display screening

Indexed keywords

ANTIBODY ENGINEERING; COVALENT ATTACHMENT; OXIDASE; PEROXIDASE; PHAGE DISPLAY LIBRARIES; PHAGE DISPLAY SCREENING; REPORTER MOLECULES; SINGLE-DOMAIN ANTIBODIES;

BINDERS; COENZYMES; DEPOSITION; SURFACE REACTIONS;

ANTIBODIES;

BIOTIN; CATALASE; GLUCOSE OXIDASE; PEROXIDASE; STREPTAVIDIN;

ANTIBODY LIBRARY; ANTIBODY SCREENING; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; ARTIODACTYLA; BACTERIOPHAGE; BIOTINYLATION; CATALYSED REPORTER DEPOSITION; CONJUGATION; COVALENT BOND; DISULFIDE BOND; ENZYME MECHANISM; HISTOCHEMISTRY; NONHUMAN; PHAGE DISPLAY; PHAGEMID; PRIORITY JOURNAL; PROTEIN TARGETING; PSEUDOMONAS AERUGINOSA; SURFACE PROPERTY; VIRION;

ANTIBODY ENGINEERING; CATALYSED REPORTER DEPOSITION; OXIDASE; PEROXIDASE; PHAGE DISPLAY SCREENING;

ANIMALS; ANTIBODY AFFINITY; ANTIGENS; BIOTINYLATION; CAMELIDS, NEW WORLD; ENZYMES, IMMOBILIZED; OXIDATION-REDUCTION; OXIDOREDUCTASES; PEPTIDE LIBRARY; PERIODIC ACID; PEROXIDASE; SINGLE-DOMAIN ANTIBODIES;

EID: 84892946865     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzt060     Document Type: Article

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