Inhibited experimental corneal neovascularization by neutralizing anti-SDF-1α antibody

International Journal of Ophthalmology

Volumn 5, Issue 1, 2012, Pages 7-12

  Liu, Gao Qin ^a   Lu, Pei Rong ^a   Li, Long Biao ^a   Zhang, Xue Guang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Alkali injury; Chemokine; Corneal neovascularization

Indexed keywords

EID: 84892940665     PISSN: 22223959     EISSN: 22274898     Source Type: Journal    
DOI: 10.3980/j.issn.2222-3959.2012.01.02     Document Type: Article

References (21)

1. Ambati BK, Nozaki M, Singh N., Takeda A, Jani PD, Suthar T, Albuquerque R.J., Richter E., Sakurai E, Newcomb MT, Kleinman M.E., Caldwell RB, Lin Q, Ogura Y, Orecchia A., Samuelson DA, Agnew DW, St Leger J, Green WR, Mahasreshti P.J., Curiel DT, Kwan D, Marsh H, Ikeda S, Leiper LJ, Collinson JM, Bogdanovich S, Khurana TS, Shibuya M, Baldwin ME, Ferrara N, Gerber HP, De Falco S, Witta J, Baffi JZ, Raisler BJ, Ambati J. Corneal avascularity is due to soluble VEGF receptor-1. Nature. 2006; 443:993-997.
2. Zhang S, Ma J. Ocular neovascularization: Implication of endogenous angiogenic inhibitors and potential therapy. Prog Retin Eye Res. 2007; 26:1-37.
3. Aiuti A, Webb IJ, Bleul C, Springer T., Gutierrez-Ramos JC. The chemokine SDF-1 is a chemoattractant for human CD34+ progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood. J Exp Med. 1997; 185:111-120.
4. Bleul CC, Fuhlbrigge RC, Casasnovas J.M., Aiuti A., Springer TA A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) J Exp Med. 1996; 184:1101-1109.
5. Pablos JL, Amara A, Bouloc A., Santiago B, Caruz A, Galindo M., Delaunay T, Virelizier JL, Arenzana-Seisdedos F. Stromal-cell derived factor is expressed by dendritic cells and endothelium in human skin. Am J Pathol. 1999; 155:1577-1586.
6. Sengupta N, Caballero S, Mames R.N., Butler JM, Scott EW, Grant MB The role of adult bone marrow-derived stem cells in choroidal neovascularization. Invest Ophthalmol Vis Sci. 2003; 44:4908-4913.
7. Murdoch C, Monk PN, Finn A. CXC chemokine receptor expression on human endothelial cells. Cytokine. 1999; 11:704-712.
8. Sengupta N, Caballero S, Mames R.N., Butler JM, Scott EW, Grant MB Paracrine modulation of CXCR4 by IGF-1 and VEGF: implications for choroidal neovascularization. Invest Ophthalmol Vis Sci. 2010; 51:2697-2704.
9. Lu P, Li L, Kuno K., Wu Y, Baba T, Li Y.Y., Zhang X., Mukaida N. Protective roles of the fractalkine/CX3CL1-CX3CR1 axis against alkali-induced corneal neovascularization through enhanced anti-angiogenic factor expression. J Immunol. 2008; 108:4283-4291.
10. Lu P, Li L, Mukaida N., Zhang X. Alkali-induced corneal neovascularization is independent of CXCR2-mediated neutrophil infiltration. Cornea. 2007; 26:199-206.
11. Liu G, Lu P, Li L., Jin H, He X, Mukaida N., Zhang X. Critical role of SDF-1α-induced progenitor cell recruitment and macrophage VEGF production in the experimental corneal neovascularization. Molecular Vision. 2011; 17:2129-2138.
12. Kucia M, Jankowski K, Reca R., Wysoczynski M, Bandura L, Allendorf D.J., Zhang J., Ratajczak J, Ratajczak MZ CXCR4-SDF-1 signalling, locomotion, chemotaxis and adhesion. J Mol Histol. 2004; 35:233-245.
13. Takahashi H, Yanagi Y, Tamaki Y., Muranaka K, Usui T, Sata M. Contribution of bone-marrow-derived cells to choroidal neovascularization. Biochem Biophys Res Commun. 2004; 320:372-375.
14. Ohki Y, Heissig B, Sato Y., Akiyama H, Zhu Z, Hicklin D.J., Shimada K., Ogawa H, Daida H, Hattori K., Ohsaka A. Granulocyte colony-stimulating factor promotes neovascularization by releasing vascular endothelial growth factor from neutrophils. FASEB J. 2005; 19:2005-2007.
15. Sawano A, Iwai S, Sakurai Y., Ito M, Shitara K, Nakahata T., Shibuya M. Vascular endothelial growth factor receptor-1 (Flt-1) is a novel cell surface marker for the lineage of monocyte-macrophages in human. Blood. 2001; 97:785-791.
16. Zagzag D, Lukyanov Y, Lan L., Ali MA, Esencay M, Mendez O, Yee H., Voura EB, Newcomb EW Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Lab Invest. 2006; 86:1221-1232.
17. Liang Z, Brooks J, Willard M., Liang K, Yoon Y, Kang S., Shim H. CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway. Biochem Biophys Res Commun. 2007; 359:716-722.
18. Stellos K, Langer H, Daub K., Schoenberger T, Gauss A, Geisler T., Bigalke B, Mueller I, Schumm M., Schaefer I, Seizer P, Kraemer B.F., Siegel-Axel D, May AE, Lindemann S, Gawaz M. Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cells. Circulation. 2008; 117:206-215.
19. Kijowski J, Baj-Krzyworzeka M, Majka M., Reca R, Marquez LA, Christofidou-Solomidou M, Janowska-Wieczorek A, Ratajczak MZ The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells. Stem Cells. 2001; 19:453-466.
20. Sameermahmood Z, Balasubramanyam M, Saravanan T., Rema M. Curcumin modulates SDF-1alpha/CXCR4-induced migration of human retinal endothelial cells (HRECs) Invest Ophthalmol Vis Sci. 2008; 49:3305-3311.
21. Salcedo R, Zhang X, Young H.A., Michael N., Wasserman K, Ma WH, Martins-Green M, Murphy W.J., Oppenheim JJ Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells. Blood. 2003; 102:1966-1977.