메뉴 건너뛰기




Volumn 458, Issue 1, 2014, Pages 57-67

CIP75 (connexin43-interacting protein of 75 kDa) mediates the endoplasmic reticulum dislocation of connexin43

Author keywords

Connexin; Connexin43 interacting protein of 75 kDa (CIP75); Endoplasmic reticulum associated degradation (ERAD); Proteasome; Protein degradation; Protein translocation

Indexed keywords

CIP 75 PROTEIN; CONNEXIN 43; PROTEASOME; PROTEIN; SHORT HAIRPIN RNA; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 84892937951     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20131247     Document Type: Article
Times cited : (15)

References (48)
  • 1
    • 0030013202 scopus 로고    scopus 로고
    • Connexins, connexons, and intercellular communication
    • Goodenough, D. A., Goliger, J. A. and Paul, D. L. (1996) Connexins, connexons, and intercellular communication. Annu. Rev. Biochem. 65, 475-502
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 475-502
    • Goodenough, D.A.1    Goliger, J.A.2    Paul, D.L.3
  • 3
    • 8444245596 scopus 로고    scopus 로고
    • Connexins and cell signaling in development and disease
    • Wei, C. J., Xu, X. and Lo, C. W. (2004) Connexins and cell signaling in development and disease. Annu. Rev. Cell Dev. Biol. 20, 811-838
    • (2004) Annu. Rev. Cell Dev. Biol. , vol.20 , pp. 811-838
    • Wei, C.J.1    Xu, X.2    Lo, C.W.3
  • 4
    • 0033002783 scopus 로고    scopus 로고
    • Genetic diseases and gene knockouts reveal diverse connexin functions
    • White, T. W. and Paul, D. L. (1999) Genetic diseases and gene knockouts reveal diverse connexin functions. Annu. Rev. Physiol. 61, 283-310
    • (1999) Annu. Rev. Physiol. , vol.61 , pp. 283-310
    • White, T.W.1    Paul, D.L.2
  • 5
    • 77952929243 scopus 로고    scopus 로고
    • Implications and challenges of connexin connections to cancer
    • Naus, C. C. and Laird, D. W. (2010) Implications and challenges of connexin connections to cancer. Nat. Rev. Cancer. 10, 435-441
    • (2010) Nat. Rev. Cancer. , vol.10 , pp. 435-441
    • Naus, C.C.1    Laird, D.W.2
  • 6
    • 1942438659 scopus 로고    scopus 로고
    • Incorporation of connexins into plasma membranes and gap junctions
    • Martin, P. E. and Evans, W. H. (2004) Incorporation of connexins into plasma membranes and gap junctions. Cardiovasc. Res. 62, 378-387
    • (2004) Cardiovasc. Res. , vol.62 , pp. 378-387
    • Martin, P.E.1    Evans, W.H.2
  • 7
    • 51749110724 scopus 로고    scopus 로고
    • Remodelling of gap junctions and connexin expression in diseased myocardium
    • Severs, N. J., Bruce, A. F., Dupont, E. and Rothery, S. (2008) Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovasc. Res. 80, 9-19
    • (2008) Cardiovasc. Res. , vol.80 , pp. 9-19
    • Severs, N.J.1    Bruce, A.F.2    Dupont, E.3    Rothery, S.4
  • 8
    • 0034941724 scopus 로고    scopus 로고
    • Cardiac gap junction channels: Modulation of expression and channel properties
    • van Veen, A. A., van Rijen, H. V. and Opthof, T. (2001) Cardiac gap junction channels: Modulation of expression and channel properties. Cardiovasc. Res. 51, 217-229
    • (2001) Cardiovasc. Res. , vol.51 , pp. 217-229
    • Van Veen, A.A.1    Van Rijen, H.V.2    Opthof, T.3
  • 9
    • 41249084806 scopus 로고    scopus 로고
    • Closing the gap on autosomal dominant connexin-26 and connexin-43 mutants linked to human disease
    • Laird, D. W. (2008) Closing the gap on autosomal dominant connexin-26 and connexin-43 mutants linked to human disease. J. Biol. Chem. 283, 2997-3001
    • (2008) J. Biol. Chem. , vol.283 , pp. 2997-3001
    • Laird, D.W.1
  • 11
    • 0032555956 scopus 로고    scopus 로고
    • Rapid turnover of connexin43 in the adult rat heart
    • Beardslee, M. A., Laing, J. G., Beyer, E. C. and Saffitz, J. E. (1998) Rapid turnover of connexin43 in the adult rat heart. Circ. Res. 83, 629-635
    • (1998) Circ. Res. , vol.83 , pp. 629-635
    • Beardslee, M.A.1    Laing, J.G.2    Beyer, E.C.3    Saffitz, J.E.4
  • 12
    • 0019603292 scopus 로고
    • Five-hour half-life of mouse liver gap-junction protein
    • Fallon, R. F. and Goodenough, D. A. (1981) Five-hour half-life of mouse liver gap-junction protein. J. Cell. Biol. 90, 521-526
    • (1981) J. Cell. Biol. , vol.90 , pp. 521-526
    • Fallon, R.F.1    Goodenough, D.A.2
  • 13
    • 0028859207 scopus 로고
    • Expression of multiple connexins in cultured neonatal rat ventricular myocytes
    • Darrow, B. J., Laing, J. G., Lampe, P. D., Saffitz, J. E. and Beyer, E. C. (1995) Expression of multiple connexins in cultured neonatal rat ventricular myocytes. Circ. Res. 76, 381-387
    • (1995) Circ. Res. , vol.76 , pp. 381-387
    • Darrow, B.J.1    Laing, J.G.2    Lampe, P.D.3    Saffitz, J.E.4    Beyer, E.C.5
  • 14
    • 0026025267 scopus 로고
    • Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes
    • Laird, D. W., Puranam, K. L. and Revel, J. P. (1991) Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes. Biochem. J. 273, 67-72
    • (1991) Biochem. J. , vol.273 , pp. 67-72
    • Laird, D.W.1    Puranam, K.L.2    Revel, J.P.3
  • 15
    • 0034682799 scopus 로고    scopus 로고
    • Regulation of connexin degradation as a mechanism to increase gap junction assembly and function
    • Musil, L. S., Le, A. C., VanSlyke, J. K. and Roberts, L. M. (2000) Regulation of connexin degradation as a mechanism to increase gap junction assembly and function. J. Biol. Chem. 275, 25207-25215
    • (2000) J. Biol. Chem. , vol.275 , pp. 25207-25215
    • Musil, L.S.1    Le, A.C.2    VanSlyke, J.K.3    Roberts, L.M.4
  • 16
    • 84874614537 scopus 로고    scopus 로고
    • Proteins and mechanisms regulating gap-junction assembly internalization and degradation
    • Thevenin, A. F., Kowal, T. J., Fong, J. T., Kells, R. M., Fisher, C. G. and Falk, M. M. (2013) Proteins and mechanisms regulating gap-junction assembly, internalization, and degradation. Physiology 28, 93-116
    • (2013) Physiology , vol.28 , pp. 93-116
    • Thevenin, A.F.1    Kowal, T.J.2    Fong, J.T.3    Kells, R.M.4    Fisher, C.G.5    Falk, M.M.6
  • 17
    • 75149159657 scopus 로고    scopus 로고
    • The gap junction proteome and its relationship to disease
    • Laird, D. W. (2010) The gap junction proteome and its relationship to disease. Trends Cell Biol. 20, 92-101
    • (2010) Trends Cell Biol , vol.20 , pp. 92-101
    • Laird, D.W.1
  • 18
    • 84866012615 scopus 로고    scopus 로고
    • Degradation of connexins through the proteasomal, endolysosomal and phagolysosomal pathways
    • Su, V., Cochrane, K. and Lau, A. F. (2012) Degradation of connexins through the proteasomal, endolysosomal and phagolysosomal pathways. J. Membr. Biol. 245, 389-400
    • (2012) J. Membr. Biol. , vol.245 , pp. 389-400
    • Su, V.1    Cochrane, K.2    Lau, A.F.3
  • 19
    • 14044272826 scopus 로고    scopus 로고
    • Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation
    • Lan, Z., Kurata, W. E., Martyn, K. D., Jin, C. and Lau, A. F. (2005) Novel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradation. Biochemistry 44, 2385-2396
    • (2005) Biochemistry , vol.44 , pp. 2385-2396
    • Lan, Z.1    Kurata, W.E.2    Martyn, K.D.3    Jin, C.4    Lau, A.F.5
  • 20
    • 84881432610 scopus 로고    scopus 로고
    • The connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane
    • Cochrane, K., Su, V. and Lau, A. F. (2013) The connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane. Cell Commun. Adhes. 20, 53-66
    • (2013) Cell Commun. Adhes. , vol.20 , pp. 53-66
    • Cochrane, K.1    Su, V.2    Lau, A.F.3
  • 21
    • 0037193468 scopus 로고    scopus 로고
    • Dislocation and degradation from the ER are regulated by cytosolic stress
    • VanSlyke, J. K. and Musil, L. S. (2002) Dislocation and degradation from the ER are regulated by cytosolic stress. J. Cell. Biol. 157, 381-394
    • (2002) J. Cell. Biol. , vol.157 , pp. 381-394
    • VanSlyke, J.K.1    Musil, L.S.2
  • 22
    • 3242671372 scopus 로고    scopus 로고
    • A field guide to ubiquitylation
    • Fang, S. and Weissman, A. M. (2004) A field guide to ubiquitylation. Cell. Mol. Life Sci. 61, 1546-1561
    • (2004) Cell. Mol. Life Sci. , vol.61 , pp. 1546-1561
    • Fang, S.1    Weissman, A.M.2
  • 23
    • 68949221689 scopus 로고    scopus 로고
    • Ubiquitin-like and ubiquitin-associated domain proteins: Significance in proteasomal degradation
    • Su, V. and Lau, A. F. (2009) Ubiquitin-like and ubiquitin-associated domain proteins: Significance in proteasomal degradation. Cell. Mol. Life Sci. 66, 2819-2833
    • (2009) Cell. Mol. Life Sci. , vol.66 , pp. 2819-2833
    • Su, V.1    Lau, A.F.2
  • 24
    • 41949131052 scopus 로고    scopus 로고
    • A novel connexin43-interacting protein, CIP75, which belongs to the UbL-UBA protein family, regulates the turnover of connexin43
    • Li, X., Su, V., Kurata, W. E., Jin, C. and Lau, A. F. (2008) A novel connexin43-interacting protein, CIP75, which belongs to the UbL-UBA protein family, regulates the turnover of connexin43. J. Biol. Chem. 283, 5748-5759
    • (2008) J. Biol. Chem. , vol.283 , pp. 5748-5759
    • Li, X.1    Su, V.2    Kurata, W.E.3    Jin, C.4    Lau, A.F.5
  • 25
    • 78650388517 scopus 로고    scopus 로고
    • Ubiquitin-independent proteasomal degradation of endoplasmic reticulum-localized connexin43 mediated by CIP75
    • Su, V., Nakagawa, R., Koval, M. and Lau, A. F. (2010) Ubiquitin-independent proteasomal degradation of endoplasmic reticulum-localized connexin43 mediated by CIP75. J. Biol. Chem. 285, 40979-40990
    • (2010) J. Biol. Chem. , vol.285 , pp. 40979-40990
    • Su, V.1    Nakagawa, R.2    Koval, M.3    Lau, A.F.4
  • 26
    • 56249108370 scopus 로고    scopus 로고
    • Ubiquitin-independent degradation of proteins by the proteasome
    • Jariel-Encontre, I., Bossis, G. and Piechaczyk, M. (2008) Ubiquitin-independent degradation of proteins by the proteasome. Biochim. Biophys. Acta 1786, 153-177
    • (2008) Biochim. Biophys. Acta , vol.1786 , pp. 153-177
    • Jariel-Encontre, I.1    Bossis, G.2    Piechaczyk, M.3
  • 27
    • 0037036426 scopus 로고    scopus 로고
    • Targeted gap junction protein constructs reveal connexin-specific differences in oligomerization
    • Das Sarma, J., Wang, F. and Koval, M. (2002) Targeted gap junction protein constructs reveal connexin-specific differences in oligomerization. J. Biol. Chem. 277, 20911-20918
    • (2002) J. Biol. Chem. , vol.277 , pp. 20911-20918
    • Das Sarma, J.1    Wang, F.2    Koval, M.3
  • 28
    • 84856067520 scopus 로고    scopus 로고
    • Activation of Akt, not connexin 43 protein ubiquitination, regulates gap junction stability
    • Dunn, C. A., Su, V., Lau, A. F. and Lampe, P. D. (2012) Activation of Akt, not connexin 43 protein ubiquitination, regulates gap junction stability. J. Biol. Chem. 287, 2600-2607
    • (2012) J. Biol. Chem. , vol.287 , pp. 2600-2607
    • Dunn, C.A.1    Su, V.2    Lau, A.F.3    Lampe, P.D.4
  • 29
    • 65349097320 scopus 로고    scopus 로고
    • Generation and characterization of mouse monoclonal antibodies against CIP75, an UbL-UBA domain-containing protein
    • Larchmt
    • Su, V., Knutson, A., Lau, K., Kurata, W., Berestecky, J. and Lau, A. F. (2009) Generation and characterization of mouse monoclonal antibodies against CIP75, an UbL-UBA domain-containing protein. Hybridoma (Larchmt) 28, 79-84
    • (2009) Hybridoma , vol.28 , pp. 79-84
    • Su, V.1    Knutson, A.2    Lau, K.3    Kurata, W.4    Berestecky, J.5    Lau, A.F.6
  • 31
    • 0025149054 scopus 로고
    • Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: Essential residues near the amino terminus
    • Hope, T. J., McDonald, D., Huang, X. J., Low, J. and Parslow, T. G. (1990) Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: Essential residues near the amino terminus. J. Virol. 64, 5360-5366
    • (1990) J. Virol. , vol.64 , pp. 5360-5366
    • Hope, T.J.1    McDonald, D.2    Huang, X.J.3    Low, J.4    Parslow, T.G.5
  • 32
    • 0026654763 scopus 로고
    • Brefeldin A and the endocytic pathway. Possible implications for membrane traffic and sorting
    • Hunziker, W., Whitney, J. A. and Mellman, I. (1992) Brefeldin A and the endocytic pathway. Possible implications for membrane traffic and sorting. FEBS Lett. 307, 93-96
    • (1992) FEBS Lett. , vol.307 , pp. 93-96
    • Hunziker, W.1    Whitney, J.A.2    Mellman, I.3
  • 33
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • Laird, D. W. (2006) Life cycle of connexins in health and disease. Biochem. J. 394, 527-543
    • (2006) Biochem. J. , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 34
    • 0031281674 scopus 로고    scopus 로고
    • Degradation of connexin43 gap junctions involves both the proteasome and the lysosome
    • Laing, J. G., Tadros, P. N., Westphale, E. M. and Beyer, E. C. (1997) Degradation of connexin43 gap junctions involves both the proteasome and the lysosome. Exp. Cell Res. 236, 482-492
    • (1997) Exp. Cell Res. , vol.236 , pp. 482-492
    • Laing, J.G.1    Tadros, P.N.2    Westphale, E.M.3    Beyer, E.C.4
  • 35
    • 82255161944 scopus 로고    scopus 로고
    • Road to ruin: Targeting proteins for degradation in the endoplasmic reticulum
    • Smith, M. H., Ploegh, H. L. and Weissman, J. S. (2011) Road to ruin: Targeting proteins for degradation in the endoplasmic reticulum. Science 334, 1086-1090
    • (2011) Science , vol.334 , pp. 1086-1090
    • Smith, M.H.1    Ploegh, H.L.2    Weissman, J.S.3
  • 36
    • 0042030808 scopus 로고    scopus 로고
    • Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells
    • Qin, H., Shao, Q., Igdoura, S. A., Alaoui-Jamali, M. A. and Laird, D. W. (2003) Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells. J. Biol. Chem. 278, 30005-30014
    • (2003) J. Biol. Chem. , vol.278 , pp. 30005-30014
    • Qin, H.1    Shao, Q.2    Igdoura, S.A.3    Alaoui-Jamali, M.A.4    Laird, D.W.5
  • 37
    • 0034047183 scopus 로고    scopus 로고
    • Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins
    • VanSlyke, J. K., Deschenes, S. M. and Musil, L. S. (2000) Intracellular transport, assembly, and degradation of wild-type and disease-linked mutant gap junction proteins. Mol. Biol. Cell 11, 1933-1946
    • (2000) Mol. Biol. Cell , vol.11 , pp. 1933-1946
    • VanSlyke, J.K.1    Deschenes, S.M.2    Musil, L.S.3
  • 40
    • 79952792541 scopus 로고    scopus 로고
    • Autophagy: A pathway that contributes to connexin degradation
    • Lichtenstein, A., Minogue, P. J., Beyer, E. C. and Berthoud, V. M. (2011) Autophagy: A pathway that contributes to connexin degradation. J. Cell. Sci. 124, 910-920
    • (2011) J. Cell. Sci. , vol.124 , pp. 910-920
    • Lichtenstein, A.1    Minogue, P.J.2    Beyer, E.C.3    Berthoud, V.M.4
  • 41
    • 77951248828 scopus 로고    scopus 로고
    • Autophagy: Links with the proteasome
    • Lamark, T. and Johansen, T. (2010) Autophagy: Links with the proteasome. Curr. Opin. Cell Biol. 22, 192-198
    • (2010) Curr. Opin. Cell Biol. , vol.22 , pp. 192-198
    • Lamark, T.1    Johansen, T.2
  • 42
    • 0037834898 scopus 로고    scopus 로고
    • Ubiquitin-independent proteolytic functions of the proteasome
    • Orlowski, M. and Wilk, S. (2003) Ubiquitin-independent proteolytic functions of the proteasome. Arch. Biochem. Biophys. 415, 1-5
    • (2003) Arch. Biochem. Biophys. , vol.415 , pp. 1-5
    • Orlowski, M.1    Wilk, S.2
  • 43
    • 0037414834 scopus 로고    scopus 로고
    • Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome
    • Shringarpure, R., Grune, T., Mehlhase, J. and Davies, K. J. (2003) Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. J. Biol. Chem. 278, 311-318
    • (2003) J. Biol. Chem. , vol.278 , pp. 311-318
    • Shringarpure, R.1    Grune, T.2    Mehlhase, J.3    Davies, K.J.4
  • 44
    • 84861633611 scopus 로고    scopus 로고
    • Channel-independent influence of connexin 43 on cell migration
    • Kameritsch, P., Pogoda, K. and Pohl, U. (2012) Channel-independent influence of connexin 43 on cell migration. Biochim. Biophys. Acta 1818, 1993-2001
    • (2012) Biochim. Biophys. Acta , vol.1818 , pp. 1993-2001
    • Kameritsch, P.1    Pogoda, K.2    Pohl, U.3
  • 46
    • 20444420130 scopus 로고    scopus 로고
    • Gap junction- and hemichannel-independent actions of connexins
    • Jiang, J. X. and Gu, S. (2005) Gap junction- and hemichannel-independent actions of connexins. Biochim. Biophys. Acta 1711, 208-214
    • (2005) Biochim. Biophys. Acta , vol.1711 , pp. 208-214
    • Jiang, J.X.1    Gu, S.2
  • 47
    • 41449104964 scopus 로고    scopus 로고
    • Cardiac connections-The antiarrhythmic solution?
    • Duffy, H. S. (2008) Cardiac connections-the antiarrhythmic solution? N. Engl. J. Med. 358, 1397-1398
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1397-1398
    • Duffy, H.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.