Antibodies to N-methyl-D-aspartate and other synaptic receptors in choreoathetosis and relapsing symptoms post-herpes virus encephalitis

Movement Disorders

Volumn 29, Issue 1, 2014, Pages 3-6

  Titulaer, Maarten J ^a   Leypoldt, Frank ^b   Dalmau, Josep ^b,c,d  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b HOSPITAL CLÍNIC   (Spain)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTICONVULSIVE AGENT; CYCLOPHOSPHAMIDE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; EPITOPE; IMMUNOGLOBULIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR ANTIBODY; RITUXIMAB; STEROID; SYNAPSE RECEPTOR;

AGGRESSION; AGITATION; ANARTHRIA; ANTIVIRAL THERAPY; CELL SURFACE; CEREBROSPINAL FLUID; CHOREA; CHOREA MINOR; CHOREOATHETOSIS; CONSCIOUSNESS DISORDER; DEMYELINATION; DETERIORATION; DISEASE COURSE; DYSTONIA; EDITORIAL; ENCEPHALOMALACIA; FEVER; FOLLOW UP; GILLES DE LA TOURETTE SYNDROME; HEMIBALLISM; HERPES SIMPLEX ENCEPHALITIS; HERPES SIMPLEX VIRUS; HUMAN; HYPOVENTILATION; IMMUNE RESPONSE; IMMUNOCOMPROMISED PATIENT; IMMUNOTHERAPY; IRRITABILITY; MOLECULAR MIMICRY; MOTOR DYSFUNCTION; MUSCLE WEAKNESS; NEUROIMAGING; NEUROLOGICAL COMPLICATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OROFACIAL DYSKINESIA; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RELAPSE; SLEEP DISORDER; STEROID THERAPY; TONIC CLONIC SEIZURE; TREATMENT RESPONSE; WHITE MATTER;

ATHETOSIS; AUTOANTIBODIES; CHOREA; ENCEPHALITIS, HERPES SIMPLEX; HUMANS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 84892913890     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25716     Document Type: Editorial

References (24)

1. Steiner I, Kennedy PG, Pachner AR. The neurotropic herpes viruses: herpes simplex and varicella-zoster. Lancet Neurol 2007;6:1015-1028.
2. Skoldenberg B, Aurelius E, Hjalmarsson A, et al. Incidence and pathogenesis of clinical relapse after herpes simplex encephalitis in adults. J Neurol 2006;253:163-170.
3. Schleede L, Bueter W, Baumgartner-Sigl S, et al. Pediatric herpes simplex virus encephalitis: a retrospective multicenter experience. J Child Neurol 2013;28:321-331.
4. De Tiège X, Rozenberg F, Des Portes V, Lobut JB, Lebon P, Ponsot G, Héron B. Herpes simplex encephalitis relapses in children: differentiation of two neurologic entities. Neurology 2003;61:241-243.
5. Hargrave DR, Webb DW. Movement disorders in association with herpes simplex virus encephalitis in children: a review. Dev Med Child Neurol 1998;40:640-642.
6. Wang HS, Kuo MF, Huang SC, Chou ML. Choreoathetosis as an initial sign of relapsing of herpes simplex encephalitis. Pediatr Neurol 1994;11:341-345.
7. Kullnat MW, Morse RP. Choreoathetosis after herpes simplex encephalitis with basal ganglia involvement on MRI. Pediatrics 2008;121:e1003-e1007.
8. Ito Y, Kimura H, Yabuta Y, Ando Y, Murakami T, Shiomi M, Morishima T. Exacerbation of herpes simplex encephalitis after successful treatment with acyclovir. Clin Infect Dis 2000;30:185-187.
9. De Tiège X, De Laet C, Mazoin N, Christophe C, Mewasingh LD, Wetzburger C, Dan B. Postinfectious immune-mediated encephalitis after pediatric herpes simplex encephalitis. Brain Dev 2005;27:304-307.
10. Sellner J, Dvorak F, Zhou Y, Haas J, Kehm R, Wildemann B, Meyding-Lamade U. Acute and long-term alteration of chemokine mRNA expression after anti-viral and anti-inflammatory treatment in herpes simplex virus encephalitis. Neurosci Lett 2005;374:197-202.
11. Meyding-Lamade UK, Oberlinner C, Rau PR, et al. Experimental herpes simplex virus encephalitis: a combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities. J Neurovirol 2003;9:118-125.
12. Prüss H, Finke C, Holtje M, et al. N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis. Ann Neurol 2012;72:902-911.
13. Armangue T, Titulaer MJ, Malaga I, Bataller L, Gabilondo I, Graus F, Dalmau J. Pediatric anti-N-methyl-D-aspartate receptor encephalitis-clinical analysis and novel findings in a series of 20 patients. J Pediatr 2013;162:850-856.
14. Mohammad S, Sinclair K, Pillai S, et al. Herpes simplex encephalitis relapse with chorea is associated with autoantibodies to NMDA receptor or dopamine-2 receptor. Mov Disord 2014;29:117-122.
15. Hacohen Y, Deiva K, Pettingill P, et al. N-Methyl-D-aspartate receptor (NMDAR) antibodies in post herpes simplex virus encephalitis (HSVE) neurological relapse. Mov Disord 2014;29:90-96.
16. Leypoldt F, Tjho-Heslinga R, Aguilar E, et al. Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis-a case report. Neurology 2013, Oct 2, DOI: 10.1212/WNL.0b013e3182a9f531.
17. Dalmau J, Gleichman AJ, Hughes EG, et al. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol 2008;7:1091-1098.
18. Baizabal-Carvallo JF, Stocco A, Muscal E, Jankovic J. The spectrum of movement disorders in children with anti-NMDA receptor encephalitis. Mov Disord 2013;28:543-547.
19. Titulaer MJ, McCracken L, Gabilondo I, et al. Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol 2013;12:157-165.
20. Florance NR, Davis RL, Lam C, et al. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol 2009;66:11-18.
21. Dalmau J, Lancaster E, Martinez-Hernandez E, Rosenfeld MR, Balice-Gordon R. Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. Lancet Neurol 2011;10:63-74.
22. Hughes EG, Peng X, Gleichman AJ, et al. Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. J Neurosci 2010;30:5866-5875.
23. Dale RC, Merheb V, Pillai S, et al. Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders. Brain 2012;135:3453-3468.
24. Pradhan S, Gupta RK, Singh MB, Mathur A. Biphasic illness pattern due to early relapse in Japanese-B virus encephalitis. J Neurol Sci 2001;183:13-18.