-
1
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
Lipinski C.A., Lombardo F., Dominy B.W., Feeney P.J. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 2001, 46:3-26.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
2
-
-
34547864243
-
Delivery strategies for poorly water-soluble drugs
-
Fahr A., Liu X. Delivery strategies for poorly water-soluble drugs. Expert Opin. Drug Deliv. 2007, 4:403-416.
-
(2007)
Expert Opin. Drug Deliv.
, vol.4
, pp. 403-416
-
-
Fahr, A.1
Liu, X.2
-
3
-
-
0021948029
-
Qinghaosu (artemisinin): an antimalarial drug from China
-
Klayman D.L. Qinghaosu (artemisinin): an antimalarial drug from China. Science 1985, 228:1049-1055.
-
(1985)
Science
, vol.228
, pp. 1049-1055
-
-
Klayman, D.L.1
-
4
-
-
0029986996
-
Detection of apoptosis in KG-1a leukemic cells treated with investigational drugs
-
Efferth T., Rücker G., Falkenberg M., Manns D., Olbrich A., Fabry U., Osieka R. Detection of apoptosis in KG-1a leukemic cells treated with investigational drugs. Arzneimittelforschung. 1996, 46:196-200.
-
(1996)
Arzneimittelforschung.
, vol.46
, pp. 196-200
-
-
Efferth, T.1
Rücker, G.2
Falkenberg, M.3
Manns, D.4
Olbrich, A.5
Fabry, U.6
Osieka, R.7
-
5
-
-
0029037444
-
Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin
-
Lai H., Sing N.P. Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin. Cancer Lett. 1995, 91:41-46.
-
(1995)
Cancer Lett.
, vol.91
, pp. 41-46
-
-
Lai, H.1
Sing, N.P.2
-
6
-
-
0035315838
-
The anti-malarial artesunate is also active against cancer
-
Efferth T., Dunstan H., Sauerbrey A., Miyachi H., Chitambar C.R. The anti-malarial artesunate is also active against cancer. Int. J. Oncol. 2001, 18:767-773.
-
(2001)
Int. J. Oncol.
, vol.18
, pp. 767-773
-
-
Efferth, T.1
Dunstan, H.2
Sauerbrey, A.3
Miyachi, H.4
Chitambar, C.R.5
-
7
-
-
0042844638
-
Molecular modes of action of artesunate in tumor cell lines
-
Efferth T., Sauerbrey A., Olbrich A., Gebhart E., Rauch P., Weber H.O., Hengstler J.G., Halatsch M.E., Volm M., Tew K.D., Ross D.D., Funk J.O. Molecular modes of action of artesunate in tumor cell lines. Mol. Pharmacol. 2003, 64:382-394.
-
(2003)
Mol. Pharmacol.
, vol.64
, pp. 382-394
-
-
Efferth, T.1
Sauerbrey, A.2
Olbrich, A.3
Gebhart, E.4
Rauch, P.5
Weber, H.O.6
Hengstler, J.G.7
Halatsch, M.E.8
Volm, M.9
Tew, K.D.10
Ross, D.D.11
Funk, J.O.12
-
8
-
-
63449093129
-
Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC a-1 cells
-
Lu Y., Chen T.S., Qu J.L., Pan W.L., Sun L., Wei X.B. Dihydroartemisinin (DHA) induces caspase-3-dependent apoptosis in human lung adenocarcinoma ASTC a-1 cells. J. Biomed. Sci. 2009, 16:1-15.
-
(2009)
J. Biomed. Sci.
, vol.16
, pp. 1-15
-
-
Lu, Y.1
Chen, T.S.2
Qu, J.L.3
Pan, W.L.4
Sun, L.5
Wei, X.B.6
-
9
-
-
33646984927
-
Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro
-
Kim S.J., Kim M.S., Lee J.W., Yoo H. Dihydroartemisinin enhances radiosensitivity of human glioma cells in vitro. Cancer Res. Clin. Oncol. 2006, 132:129-135.
-
(2006)
Cancer Res. Clin. Oncol.
, vol.132
, pp. 129-135
-
-
Kim, S.J.1
Kim, M.S.2
Lee, J.W.3
Yoo, H.4
-
10
-
-
1842505247
-
Design of a dissolution system for the evaluation of the release rate characteristics of artemether and dihydroartemisinin from tablets
-
Gabriëls M., Plaizier-Vercammen J. Design of a dissolution system for the evaluation of the release rate characteristics of artemether and dihydroartemisinin from tablets. Int. J. Pharm. 2004, 274:245-260.
-
(2004)
Int. J. Pharm.
, vol.274
, pp. 245-260
-
-
Gabriëls, M.1
Plaizier-Vercammen, J.2
-
11
-
-
0029868179
-
Selective high performance liquid chromatographic determination of artesunate and α- and β dihydroartemisinin in patients with falciparum malaria
-
Batty K.T., Davis T.M.E., Thu L.T.A., Binh T.Q., Anh T.K. Selective high performance liquid chromatographic determination of artesunate and α- and β dihydroartemisinin in patients with falciparum malaria. J. Chromatogr. 1996, 677:345-350.
-
(1996)
J. Chromatogr.
, vol.677
, pp. 345-350
-
-
Batty, K.T.1
Davis, T.M.E.2
Thu, L.T.A.3
Binh, T.Q.4
Anh, T.K.5
-
12
-
-
0032937301
-
In vitro binding of HSA, IgG, and HDL on liposomes of different composition and its correlation with the BLOOD/RES ratio of liposomes
-
Panagi Z., Avgoustakis K., Evangelatos G., Ithakissios D.S. In vitro binding of HSA, IgG, and HDL on liposomes of different composition and its correlation with the BLOOD/RES ratio of liposomes. Int. J. Pharm. 1999, 176:203-207.
-
(1999)
Int. J. Pharm.
, vol.176
, pp. 203-207
-
-
Panagi, Z.1
Avgoustakis, K.2
Evangelatos, G.3
Ithakissios, D.S.4
-
13
-
-
0026778635
-
Association of blood proteins with large unilamellar liposomes in vivo: relation to circulation lifetimes
-
Chonn A., Semple S.C., Cullis P.R. Association of blood proteins with large unilamellar liposomes in vivo: relation to circulation lifetimes. J. Biol. Chem. 1992, 267:18759-18765.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 18759-18765
-
-
Chonn, A.1
Semple, S.C.2
Cullis, P.R.3
-
14
-
-
28844488494
-
Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
-
Owens D., Peppas N.A. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int. J. Pharm. 2006, 307:93-102.
-
(2006)
Int. J. Pharm.
, vol.307
, pp. 93-102
-
-
Owens, D.1
Peppas, N.A.2
-
15
-
-
0026122420
-
Protein surface interactions in the presence of polyethylene oxide. 1. Simplified theory
-
Jeon S.I., Lee J.H., Andrade J.D., De Gennes P.G. Protein surface interactions in the presence of polyethylene oxide. 1. Simplified theory. J. Colloid Interface Sci. 1991, 142:49-158.
-
(1991)
J. Colloid Interface Sci.
, vol.142
, pp. 49-158
-
-
Jeon, S.I.1
Lee, J.H.2
Andrade, J.D.3
De Gennes, P.G.4
-
16
-
-
0028596084
-
Sterically stabilized liposomes: physical and biological properties
-
Woodle M.C., Newman M.S., Choen J.A. Sterically stabilized liposomes: physical and biological properties. J. Drug Target. 1994, 2:397-403.
-
(1994)
J. Drug Target.
, vol.2
, pp. 397-403
-
-
Woodle, M.C.1
Newman, M.S.2
Choen, J.A.3
-
18
-
-
65749117793
-
Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy
-
Aggarwal P., Hall J.B., McLeland C.B., Dobrovolskaia M.A., McNeil S.E. Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy. Adv. Drug Deliv. Rev. 2009, 61:428-437.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 428-437
-
-
Aggarwal, P.1
Hall, J.B.2
McLeland, C.B.3
Dobrovolskaia, M.A.4
McNeil, S.E.5
-
19
-
-
0026570605
-
The role of surface charge and hydrophilic groups on liposome clearance in vivo
-
Gabizon A., Papahadjopoulos D. The role of surface charge and hydrophilic groups on liposome clearance in vivo. Biochim. Biophys. Acta 1992, 1103:94-100.
-
(1992)
Biochim. Biophys. Acta
, vol.1103
, pp. 94-100
-
-
Gabizon, A.1
Papahadjopoulos, D.2
-
20
-
-
0035340417
-
I and pharmacokinetic study of a stable, polyethylene-glycolated liposomal doxorubicin in patients with solid tumors: the relation between pharmacokinetic property and toxicity
-
Phase
-
Hong R.L., Tseng Y.L., Phase I and pharmacokinetic study of a stable, polyethylene-glycolated liposomal doxorubicin in patients with solid tumors: the relation between pharmacokinetic property and toxicity. Cancer 2001, 91:1826-1833.
-
(2001)
Cancer
, vol.91
, pp. 1826-1833
-
-
Hong, R.L.1
Tseng, Y.L.2
-
21
-
-
85012373035
-
Diffusion of univalent ions across the lamellae of swollen phospholipids
-
Bangham A.D., Standish M.M., Watkins J.C. Diffusion of univalent ions across the lamellae of swollen phospholipids. J. Mol. Biol. 1965, 13:238-252.
-
(1965)
J. Mol. Biol.
, vol.13
, pp. 238-252
-
-
Bangham, A.D.1
Standish, M.M.2
Watkins, J.C.3
-
22
-
-
41149114651
-
Formation, physical stability and in vitro antimalarial activity of dihydroartemisinin nanosuspensions obtained by co-grinding method
-
Chingunpitak J., Puttipipatkhachorn S., Chavalitshewinkoon-Petmitr P., Tozuka Y., Moribe K., Yamamoto K. Formation, physical stability and in vitro antimalarial activity of dihydroartemisinin nanosuspensions obtained by co-grinding method. Drug Dev. Ind. Pharm. 2008, 34:314-322.
-
(2008)
Drug Dev. Ind. Pharm.
, vol.34
, pp. 314-322
-
-
Chingunpitak, J.1
Puttipipatkhachorn, S.2
Chavalitshewinkoon-Petmitr, P.3
Tozuka, Y.4
Moribe, K.5
Yamamoto, K.6
-
23
-
-
0033953073
-
Determination of liposome size distribution by flow cytometry
-
Vorauer-Uhl K., Wagner A., Borth N., Katinger H. Determination of liposome size distribution by flow cytometry. Cytometry 2000, 38:166-171.
-
(2000)
Cytometry
, vol.38
, pp. 166-171
-
-
Vorauer-Uhl, K.1
Wagner, A.2
Borth, N.3
Katinger, H.4
-
24
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P., Storeng R., Scudiero D., Monks A., McMahon J., Vistica D., Warren J.T., Bokesch H., Kenney S., Boyd M.R. New colorimetric cytotoxicity assay for anticancer-drug screening. J. Natl. Cancer Inst. 1990, 82:1107-1112.
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
25
-
-
5444257455
-
Application of NMR spectroscopy to the characterization of PEG-stabilized lipid nanoparticles
-
Garcia-Fuentes M., Torres D., Alonso M.J. Application of NMR spectroscopy to the characterization of PEG-stabilized lipid nanoparticles. Langmuir 2004, 20:8839-8845.
-
(2004)
Langmuir
, vol.20
, pp. 8839-8845
-
-
Garcia-Fuentes, M.1
Torres, D.2
Alonso, M.J.3
-
26
-
-
84858155431
-
Artemisinin and artemisinin plus curcumin liposomal formulation: enhanced antimalarial efficacy against Plasmodium berghei-infected mice
-
Isacchi B., Bergonzi M.C., Grazioso M., Righeschi C., Pietretti A., Severini C., Bilia A.R. Artemisinin and artemisinin plus curcumin liposomal formulation: enhanced antimalarial efficacy against Plasmodium berghei-infected mice. Eur. J. Pharm. 2012, 80:528-534.
-
(2012)
Eur. J. Pharm.
, vol.80
, pp. 528-534
-
-
Isacchi, B.1
Bergonzi, M.C.2
Grazioso, M.3
Righeschi, C.4
Pietretti, A.5
Severini, C.6
Bilia, A.R.7
-
27
-
-
0035476258
-
Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition
-
Raucher D., Chilkoti A. Enhanced uptake of a thermally responsive polypeptide by tumor cells in response to its hyperthermia-mediated phase transition. Cancer Res. 2001, 61:7163-7170.
-
(2001)
Cancer Res.
, vol.61
, pp. 7163-7170
-
-
Raucher, D.1
Chilkoti, A.2
-
28
-
-
0025731906
-
Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo
-
Allen T.M., Hansen C., Martin F., Redemann C., Yau-Young A. Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim. Biophys. Acta 1991, 1066:29-36.
-
(1991)
Biochim. Biophys. Acta
, vol.1066
, pp. 29-36
-
-
Allen, T.M.1
Hansen, C.2
Martin, F.3
Redemann, C.4
Yau-Young, A.5
|