Cytomegalovirus is a potential risk factor for late-onset hemorrhagic cystitis following allogeneic hematopoietic stem cell transplantation

American Journal of Hematology

Volumn 89, Issue 1, 2014, Pages 55-61

  Han, Ting Ting ^a   Xu, Lan Ping ^a   Liu, Dai Hong ^a   Liu, Kai Yan ^a   Fu, Hai Xia ^a   Zhao, Xiang Yu ^a   Zhao, Xiao Su ^a   Huang, Xiao Jun ^a  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; BUSULFAN; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYTARABINE; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; LYMPHOCYTE ANTIBODY; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; SEMUSTINE; SULFAMETHOXAZOLE; THYMOCYTE ANTIBODY;

ACUTE GRAFT VERSUS HOST DISEASE; ACUTE LIVER FAILURE; ACUTE RESPIRATORY FAILURE; ADD ON THERAPY; ADENOVIRUS; ADENOVIRUS INFECTION; ADOLESCENT; ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANTIVIRAL THERAPY; ARTICLE; BK VIRUS; BK VIRUS INFECTION; CAUSE OF DEATH; CHILD; CLINICAL ARTICLE; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; ENGRAFTMENT; FEMALE; FOLLOW UP; HEMATOPOIETIC STEM CELL; HEMORRHAGIC CYSTITIS; HERPES VIRUS INFECTION; HLA TYPING; HUMAN; IMMUNOPROPHYLAXIS; IMMUNOSUPPRESSIVE TREATMENT; INFECTION RISK; LATE ONSET HEMORRHAGIC CYSTITIS; LEUKOCYTE; MALE; MIDDLE AGED; NUCLEOTIDE SEQUENCE; OBSERVATIONAL STUDY; PNEUMOCYSTOSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT; RISK FACTOR; SCHOOL CHILD; SINGLE DRUG DOSE; TREATMENT DURATION; URINALYSIS; VIRUS LOAD; YOUNG ADULT;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; CYSTITIS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMORRHAGE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; RISK FACTORS; TIME FACTORS; TRANSPLANTATION, HOMOLOGOUS; YOUNG ADULT;

EID: 84892864291     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.23584     Document Type: Article

References (45)

1. Brugieres L, Hartmann O, Travagli JP, et al. Hemorrhagic cystitis following high-dose chemotherapy and bone marrow transplantation in children with malignancies: Incidence, clinical course, and outcome. J Clin Oncol 1989;7:194-199.
2. Russell SJ, Vowels MR, Vale T. Haemorrhagic cystitis in paediatric bone marrow transplant patients: An association with infective agents, GVHD and prior cyclophosphamide. Bone Marrow Transplant 1994;13:533-539.
3. Xu LP, Zhang HY, Huang XJ, et al. Hemorrhagic cystitis following hematopoietic stem cell transplantation: Incidence, risk factors and association with CMV reactivation and graft-versus-host disease. Chin Med J (Engl) 2007;120:1666-1671.
4. Bedi A, Miller CB, Hanson JL, et al. Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation. J Clin Oncol 1995;13:1103-1109.
5. Gorczynska E, Turkiewicz D, Rybka K, et al. Incidence, clinical outcome, and management of virus-induced hemorrhagic cystitis in children and adolescents after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2005;11:797-804.
6. Cesaro S, Facchin C, Tridello G, et al. A prospective study of BK-virus-associated haemorrhagic cystitis in paediatric patients undergoing allogeneic haematopoietic stem cell transplantation. Bone Marrow Transplant 2008;41:363-370.
7. Vose JM, Reed EC, Pippert GC, et al. Mesna compared with continuous bladder irrigation as uroprotection during high-dose chemotherapy and transplantation: A randomized trial. J Clin Oncol 1993;11:1306-1310.
8. Gaziev J, Paba P, Miano R, et al. Late-onset hemorrhagic cystitis in children after hematopoietic stem cell transplantation for thalassemia and sickle cell anemia: A prospective evaluation of polyoma (BK) virus infection and treatment with cidofovir. Biol Blood Marrow Transplant 2010;16:662-671.
9. Giraud G, Priftakis P, Bogdanovic G, et al. BK-viruria and haemorrhagic cystitis are more frequent in allogeneic haematopoietic stem cell transplant patients receiving full conditioning and unrelated-HLA-mismatched grafts. Bone Marrow Transplant 2008;41:737-742.
10. Leung AYH. Quantification of polyoma BK viruria in hemorrhagic cystitis complicating bone marrow transplantation. Blood 2001;98:1971-1978.
11. Bogdanovic G, Priftakis P, Giraud G, et al. Association between a High BK virus load in urine samples of patients with graft-versus-host disease and development of hemorrhagic cystitis after hematopoietic stem cell transplantation. J Clin Microbiol 2004;42:5394-5396.
12. Giraud G, Bogdanovic G, Priftakis P, et al. The incidence of hemorrhagic cystitis and BK-viruria in allogeneic hematopoietic stem cell recipients according to intensity of the conditioning regimen. Haematologica 2006;91:401-404.
13. Erard V, Kim HW, Corey L, et al. BK DNA viral load in plasma: Evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients. Blood 2005;106:1130-1132.
14. Hideki Akiyama TK, Sakashita C, Inoue T, et al. Adenovirus is a key pathogen in hemorrhagic cystitis associated with bone marrow transplantation. Clin Infect Dis 2001;32:1325-1330.
15. Bogdanovic G, Priftakis P, Taemmeraes B, et al. Primary BK virus (BKV) infection due to possible BKV transmission during bone marrow transplantation is not the major cause of hemorrhagic cystitis in transplanted children. Pediatr Transplant 1998;2:288-293.
16. Azzi A, Cesaro S, Laszlo D, et al. Human polyomavirus BK (BKV) load and haemorrhagic cystitis in bone marrow transplantation patients. J Clin Virol 1999;14:79-86.
17. O'Donnell PH, Swanson K, Josephson MA, et al. BK virus infection is associated with hematuria and renal impairment in recipients of allogeneic hematopoetic stem cell transplants. Biol Blood Marrow Transplant 2009;15:1038-1048, e1031.
18. Leung AY, Chan MT, Yuen KY, et al. Ciprofloxacin decreased polyoma BK virus load in patients who underwent allogeneic hematopoietic stem cell transplantation. Clin Infect Dis 2005;40:528-537.
19. Held TK, Biel SS, Nitsche A, et al. Treatment of BK virus-associated hemorrhagic cystitis and simultaneous CMV reactivation with cidofovir. Bone Marrow Transplant 2000;26:347-350.
20. Gonzalez-Fraile MI, Canizo C, Caballero D, et al. Cidofovir treatment of human polyomavirus-associated acute haemorrhagic cystitis. Transplant Infect Dis 2001;3:44-46.
21. Suparno C, Milligan DW, Moss PA, et al. Adenovirus infections in stem cell transplant recipients: recent developments in understanding of pathogenesis, diagnosis and management. Leuk Lymphoma 2004;45:873-885.
22. Shields AF, Hackman RC, Fife KH, et al. Adenovirus infections in patients undergoing bone-marrow transplantation. N Engl J Med 1985;312:529-533.
23. Akiyama H, Kurosu T, Sakashita C, et al. Adenovirus is a key pathogen in hemorrhagic cystitis associated with bone marrow transplantation. Clin Infect Dis 2001;32:1325-1330.
24. Ambinder RF, Burns W, Forman M, et al. Hemorrhagic cystitis associated with adenovirus infection in bone marrow transplantation. Archiv Intern Med 1986;146:1400-1401.
25. Miyamura K, Takeyama K, Kojima S, et al. Hemorrhagic cystitis associated with urinary excretion of adenovirus type 11 following allogeneic bone marrow transplantation. Bone Marrow Transplant 1989;4:533-535.
26. Asano Y, Kanda Y, Ogawa N, et al. Male predominance among Japanese adult patients with late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation. Bone Marrow Transplant 2003;32:1175-1179.
27. Bil-Lula I, Ussowicz M, Rybka B, et al. Hematuria due to adenoviral infection in bone marrow transplant recipients. Transplant Proc 2010;42:3729-3734.
28. Spach DH BJ, Myerson D, Mustafa MM, Bowden RA. Cytomegalovirus-induced hemorrhagic cystitis following bone marrow transplantation. Clin Infect Dis 1993;16:4.
29. Tutuncuoglu SO, Yanovich S, Ozdemirli M. CMV-induced hemorrhagic cystitis as a complication of peripheral blood stem cell transplantation: Case report. Bone Marrow Transplant 2005;36:265-266.
30. Bielorai B, Shulman LM, Rechavi G, et al. CMV reactivation induced BK virus-associated late onset hemorrhagic cystitis after peripheral blood stem cell transplantation. Bone Marrow Transplant 2001;28:613-614.
31. Arai Y, Maeda T, Sugiura H, et al. Risk factors for and prognosis of hemorrhagic cystitis after allogeneic stem cell transplantation: retrospective analysis in a single institution. Hematology 2012;17:207-214.
32. Hassan Z, Remberger M, Svenberg P, et al. Hemorrhagic cystitis: A retrospective single-center survey. Clin Transplant 2007;21:659-667.
33. Huang XJ, Liu DH, Liu KY, et al. Haploidentical hematopoietic stem cell transplantation without in vitro T-cell depletion for the treatment of hematological malignancies. Bone Marrow Transplant 2006;38:291-297.
34. Fu HX, Xu LP, Liu DH, et al. Higher proportions of peripheral CD19+CD5+ B cells predict the effect of corticosteroid in patients with late-onset hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. Chin Med J 2011;124:1517-1523.
35. Liu D, Huang X, Liu K, et al. Haploidentical hematopoietic stem cell transplantation without in vitro T cell depletion for treatment of hematological malignancies in children. Biol Blood Marrow Transplant 2008;14:469-477.
36. Thomas ED, Storb R, Clift RA, et al. Bone-marrow transplantation (second of two parts). N Engl J Med 1975;292:895-902.
37. Kondo M, Kojima S, Kato K, et al. Late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation in children. Bone Marrow Transplant 1998;22:995-998.
38. Yamamoto R, Kusumi E, Kami M, et al. Late hemorrhagic cystitis after reduced-intensity hematopoietic stem cell transplantation (RIST). Bone Marrow Transplant 2003;32:1089-1095.
39. Seber A, Shu XO, Defor T, et al. Risk factors for severe hemorrhagic cystitis following BMT. Bone Marrow Transplant 1999;23:35-40.
40. Shakiba E, Yaghobi R, Ramzi M. Prevalence of viral infections and hemorrhagic cystitis in hematopoietic stem cell transplant recipients. Exp Clin Transplant 2011;9:405-412.
41. Kling CL, Wright AT, Katz SE, et al. Dynamics of urinary polyomavirus shedding in healthy adult women. J Med Virol 2012;84:1459-1463.
42. Thakur R, Joshi K, Minz M, et al. Dual positivity of donor and recipient plasma for BK virus confers a high risk for development of bk nephropathy in renal allograft. Transplant Proc 2012;44:717-720.
43. Moens URO. Molecular biology of BK virus and clinical and basic aspects of BK virus renal infection. In: Khalili K, Stoner GL editors. Human Polyomaviruses: Molecular and Clinical Perspectives. New York: Wiley- Liss; 2001. p 215.
44. Pinto GG, Poloni JA, Carneiro LC, et al. Evaluation of different urine protocols and DNA extraction methods for quantitative detection of BK viruria in kidney transplant patients. J Virol Methods 2013;188:94-96.
45. Hale GA, Rochester RJ, Heslop HE, et al. Hemorrhagic cystitis after allogeneic bone marrow transplantation in children: Clinical characteristics and outcome. Biol Blood Marrow Transplant 2003;9:698-705.