Perfusion parameters of dynamic contrast-enhanced magnetic resonance imaging in patients with rectal cancer: Correlation with microvascular density and vascular endothelial growth factor expression

Korean Journal of Radiology

Volumn 14, Issue 6, 2013, Pages 878-885

  Kim, Yeo Eun ^a   Lim, Joon Seok ^b   Choi, Junjeong ^c   Kim, Daehong ^d   Myoung, Sungmin ^e   Kim, Myeong Jin ^b   Kim, Ki Whang ^b  

^a Seoul Medical Center   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Yonsei University Wonju College of Medicine   (South Korea)

^d National Cancer Center   (South Korea)

^e Jungwon University   (South Korea)

Author keywords

Dynamic contrast enhanced magnetic resonance imaging; MVD; Perfusion; Rectal cancer; VEGF

Indexed keywords

GADOLINIUM PENTETATE; GADOLINIUM PENTETATE MEGLUMINE; VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CANCER STAGING; DYNAMIC CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MICROVASCULAR ENDOTHELIAL CELL; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION; PROTEIN EXPRESSION; RECTUM CANCER; RETROSPECTIVE STUDY; SCORING SYSTEM; TUMOR VOLUME; VERY ELDERLY;

DYNAMIC CONTRAST-ENHANCED MAGNETIC RESONANCE IMAGING; MVD; PERFUSION; RECTAL CANCER; VEGF;

ADULT; AGED; AGED, 80 AND OVER; CONTRAST MEDIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEOPLASM STAGING; NEOVASCULARIZATION, PATHOLOGIC; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84892846504     PISSN: 12296929     EISSN: None     Source Type: Journal    
DOI: 10.3348/kjr.2013.14.6.878     Document Type: Article

References (34)

1. Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990;82:4-6
2. Choi HJ, Hyun MS, Jung GJ, Kim SS, Hong SH. Tumor angiogenesis as a prognostic predictor in colorectal carcinoma with special reference to mode of metastasis and recurrence. Oncology 1998;55:575-581
3. Brasch RC, Li KC, Husband JE, Keogan MT, Neeman M, Padhani AR, et al. In vivo monitoring of tumor angiogenesis with MR imaging. Acad Radiol 2000;7:812-823
4. Kang H, Lee HY, Lee KS, Kim JH. Imaging-based tumor treatment response evaluation: review of conventional, new, and emerging concepts. Korean J Radiol 2012;13:371-390
5. Kim JK, Jang YJ, Cho G. Multidisciplinary functional MR imaging for prostate cancer. Korean J Radiol 2009;10:535-551
6. de Lussanet QG, Backes WH, Griffioen AW, Padhani AR, Baeten CI, van Baardwijk A, et al. Dynamic contrast-enhanced magnetic resonance imaging of radiation therapy-induced microcirculation changes in rectal cancer. Int J Radiat Oncol Biol Phys 2005;63:1309-1315
7. Ceelen W, Smeets P, Backes W, Van Damme N, Boterberg T, Demetter P, et al. Noninvasive monitoring of radiotherapy induced microvascular changes using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) in a colorectal tumor model. Int J Radiat Oncol Biol Phys 2006;64:1188-1196
8. George ML, Dzik-Jurasz AS, Padhani AR, Brown G, Tait DM, Eccles SA, et al. Non-invasive methods of assessing angiogenesis and their value in predicting response to treatment in colorectal cancer. Br J Surg 2001;88:1628-1636
9. Zahra MA, Hollingsworth KG, Sala E, Lomas DJ, Tan LT. Dynamic contrast-enhanced MRI as a predictor of tumour response to radiotherapy. Lancet Oncol 2007;8:63-74
10. Atkin G, Taylor NJ, Daley FM, Stirling JJ, Richman P, Glynne Jones R, et al. Dynamic contrast-enhanced magnetic resonance imaging is a poor measure of rectal cancer angiogenesis. Br J Surg 2006;93:992-1000
11. Zhang XM, Yu D, Zhang HL, Dai Y, Bi D, Liu Z, et al. 3D dynamic contrast-enhanced MRI of rectal carcinoma at 3T: correlation with microvascular density and vascular endothelial growth factor markers of tumor angiogenesis. J Magn Reson Imaging 2008;27:1309-1316
12. Yao WW, Zhang H, Ding B, Fu T, Jia H, Pang L, et al. Rectal cancer: 3D dynamic contrast-enhanced MRI; correlation with microvascular density and clinicopathological features. Radiol Med 2011;116:366-374
13. Tofts PS, Kermode AG. Measurement of the blood-brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts. Magn Reson Med 1991;17:357-367
14. Tofts PS, Brix G, Buckley DL, Evelhoch JL, Henderson E, Knopp MV, et al. Estimating kinetic parameters from dynamic contrast-enhanced T(1)-weighted MRI of a diffusable tracer: standardized quantities and symbols. J Magn Reson Imaging 1999;10:223-232
15. Padhani AR, Liu G, Koh DM, Chenevert TL, Thoeny HC, Takahara T, et al. Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations. Neoplasia 2009;11:102-125
16. Weinmann HJ, Laniado M, Mützel W. Pharmacokinetics of GdDTPA/dimeglumine after intravenous injection into healthy volunteers. Physiol Chem Phys Med NMR 1984;16:167-172
17. Gray LH, Conger AD, Ebert M, Hornsey S, Scott OC. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 1953;26:638-648
18. Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. N Engl J Med 1991;324:1-8
19. Johnson JA, Wilson TA. A model for capillary exchange. Am J Physiol 1966;210:1299-1303
20. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-257
21. Jain RK. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 2005;307:58-62
22. Janssen MH, Aerts HJ, Kierkels RG, Backes WH, Ollers MC, Buijsen J, et al. Tumor perfusion increases during hypofractionated short-course radiotherapy in rectal cancer: sequential perfusion-CT findings. Radiother Oncol 2010;94:156-160
23. Jain RK. Transport of molecules in the tumor interstitium: a review. Cancer Res 1987;47:3039-3051
24. Brix G, Kiessling F, Lucht R, Darai S, Wasser K, Delorme S, et al. Microcirculation and microvasculature in breast tumors: pharmacokinetic analysis of dynamic MR image series. Magn Reson Med 2004;52:420-429
25. Benjaminsen IC, Brurberg KG, Ruud EB, Rofstad EK. Assessment of extravascular extracellular space fraction in human melanoma xenografts by DCE-MRI and kinetic modeling. Magn Reson Imaging 2008;26:160-170
26. Tuncbilek N, Karakas HM, Altaner S. Dynamic MRI in indirect estimation of microvessel density, histologic grade, and prognosis in colorectal adenocarcinomas. Abdom Imaging 2004;29:166-172
27. Gillies RJ, Raghunand N, Karczmar GS, Bhujwalla ZM. MRI of the tumor microenvironment. J Magn Reson Imaging 2002;16:430-450
28. Hlatky L, Hahnfeldt P, Folkman J. Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us. J Natl Cancer Inst 2002;94:883-893
29. Fujisawa T, Watanabe J, Akaboshi M, Ohno E, Kuramoto H. Immunohistochemical study on VEGF expression in endometrial carcinoma--comparison with p53 expression, angiogenesis, and tumor histologic grade. J Cancer Res Clin Oncol 2001;127:668-674
30. Giatromanolaki A, Koukourakis MI, Kakolyris S, Turley H, O'Byrne K, Scott PA, et al. Vascular endothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer. Clin Cancer Res 1998;4:3017-3024
31. Leung DW, Cachianes G, Kuang WJ, Goeddel DV, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 1989;246:1306-1309
32. Folkman J. Fundamental concepts of the angiogenic process. Curr Mol Med 2003;3:643-651
33. Fujiwaki R, Hata K, Iida K, Koike M, Miyazaki K. Immunohistochemical expression of thymidine phosphorylase vascular heterogeneity and angiogenesis using dynamic in human endometrial cancer. Gynecol Oncol 1998;68:247-252
34. Jackson A, O'Connor JP, Parker GJ, Jayson GC. Imaging tumor contrast-enhanced magnetic resonance imaging. Clin Cancer Res 2007;13:3449-3459