Age Differences in Ethanol Discrimination: Acquisition and Ethanol Dose Generalization Curves Following Multiple Training Conditions in Adolescent and Adult Rats

Alcoholism: Clinical and Experimental Research

Volumn 38, Issue 1, 2014, Pages 186-194

  Anderson, Rachel I ^a   Spear, Linda P ^a  

^a BINGHAMTON UNIVERSITY   (United States)

Author keywords

Adolescent; Discrimination; Ethanol; Pavlovian Conditioned Approach; Rat

Indexed keywords

ALCOHOL; SODIUM CHLORIDE;

ADOLESCENT; ADULT; AGE; ALCOHOL BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; DIET RESTRICTION; DISCRIMINATIVE STIMULUS; DOSE RESPONSE; DRUG DISCRIMINATION TEST; HYPOTHESIS; MALE; NONHUMAN; PERCEPTION; PRIORITY JOURNAL; RAT; RAT MODEL; TRAINING;

ANIMALIA; RATTUS;

ADOLESCENT; DISCRIMINATION; ETHANOL; PAVLOVIAN CONDITIONED APPROACH; RAT;

AGING; ALCOHOL DRINKING; ANIMALS; CONDITIONING, OPERANT; DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; MALE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84892786109     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12255     Document Type: Article

References (35)

1. Adriani W, Chiarotti F, Laviola G (1998) Elevated novelty seeking and peculiar d-amphetamine sensitization in periadolescent mice compared with adult mice. Behav Neurosci 112:1152-1166.
2. Anderson RI, Varlinskaya EI, Spear LP (2010) Ethanol-induced conditioned taste aversion in male Sprague-Dawley rats: impact of age and stress. Alcohol Clin Exp Res 34:2106-2115.
3. Andrzejewski ME, Schochet TL, Feit EC, Harris R, McKee BL, Kelley AE (2011) A comparison of adult and adolescent rat behavior in operant learning, extinction, and behavioral inhibition paradigms. Behav Neurosci 125:93-105.
4. Besheer J, Fisher KR, Durant B (2012a) Assessment of the interoceptive effects of alcohol in rats using short-term training procedures. Alcohol 46:747-755.
5. Besheer J, Fisher KR, Grondin JJ, Cannady R, Hodge CW (2012b) The effects of repeated corticosterone exposure on the interoceptive effects of alcohol in rats. Psychopharmacology 220:809-822.
6. Broadwater M, Varlinskaya EI, Spear LP (2011) Different chronic ethanol exposure regimens in adolescent and adult male rats: effects on tolerance to ethanol-induced motor impairment. Behav Brain Res 225:358-362.
7. Crissman AM, Studders SL, Becker HC (2004) Tolerance to the discriminative stimulus effects of ethanol following chronic inhalation exposure to ethanol in C57BL/6J mice. Behav Pharmacol 15:569-575.
8. Doremus TL, Brunell SC, Rajendran P, Spear LP (2005) Factors influencing elevated ethanol consumption in adolescent relative to adult rats. Alcohol Clin Exp Res 29:1796-1808.
9. Harris J (1995) Where is the child's environment? A group socialization theory of development. Psychol Rev 102:458-489.
10. Hodge CW, Grant KA, Becker HC, Besheer J, Crissman AM, Platt DM, Shannon EE, Shelton KL (2006) Understanding how the brain perceives alcohol: neurobiological basis of ethanol discrimination. Alcohol Clin Exp Res 30:203-213.
11. Holson RR, Pearce B (1992) Principles and pitfalls in the analysis of prenatal treatment effects in multiparous species. Neurotoxicol Teratol 14:221-228.
12. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council (2011) Guide for the Care and Use of Laboratory Animals. National Academy Press, Washington DC.
13. Johnston LD, O'Malley PM, Bachman JG, Schulenberg JE (2012) Monitoring the Future National Results on Adolescent Drug Use: Overview of Key Findings, 2011. Institute for Social Research, The University of Michigan, Ann Arbor.
14. Kelley AE, Schochet T, Landry CF (2004) Risk taking and novelty seeking in adolescence: introduction to part I. Ann N Y Acad Sci 1021:27-32.
15. Kostowski W, Bienkowski P (1999) Discriminative stimulus effects of ethanol: neuropharmacological characterization. Alcohol 17:63-80.
16. Krueger C, Tian L (2004) A comparison of the general linear mixed model and repeated measures ANOVA using a dataset with multiple missing data points. Biol Res Nurs 6:151-157.
17. Laviola G, Macri S, Morley-Fletcher S, Adriani W (2003) Risk-taking behavior in adolescent mice: psychobiological determinants and early epigenetic influence. Neurosci Biobehav Rev 27:19-31.
18. Markwiese BJ, Acheson SK, Levin ED, Wilson WA, Swartzwelder HS (1998) Differential effects of ethanol on memory in adolescent and adult rats. Alcohol Clin Exp Res 22:416-421.
19. Palmatier MI, Peterson JL, Wilkinson JL, Bevins RA (2004) Nicotine serves as a feature-positive modulator of Pavlovian appetitive conditioning in rats. Behav Pharmacol 15:183-194.
20. Palmatier MI, Wilkinson JL, Metschke DM, Bevins RA (2005) Stimulus properties of nicotine, amphetamine, and chlordiazepoxide as positive features in a Pavlovian appetitive discrimination task in rats. Neuropsychopharmacology 30:731-741.
21. Reichel CM, Wilkinson JL, Bevins RA (2007) Methamphetamine functions as a positive and negative drug feature in a Pavlovian appetitive discrimination task. Behav Pharmacol 18:755-765.
22. Schechter MD (1992) Ethanol-produced interoceptive stimuli are time dependent in selectively bred HAS and LAS rats. Alcohol 9:117-122.
23. Schramm-Sapyta NL, DiFeliceantonio AG, Foscue E, Glowacz S, Haseeb N, Wang N, Zhou C, Kuhn CM (2010) Aversive effects of ethanol in adolescent versus adult rats: potential causes and implication for future drinking. Alcohol Clin Exp Res 34:2061-2069.
24. Shippenberg TS, Altshuler HL (1985) A drug discrimination analysis of ethanol-induced behavioral excitation and sedation: the role of endogenous opiate pathways. Alcohol 2:197-201.
25. Silveri MM, Spear LP (1998) Decreased sensitivity to the hypnotic effects of ethanol early in ontogeny. Alcohol Clin Exp Res 22:670-676.
26. Spear LP (2000) The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev 24:417-463.
27. Spear LP (2010) The Behavioral Neuroscience of Adolescence. W. W. Norton, New York.
28. Substance Abuse and Mental Health Services Administration (2008) Results from the 2007 National Survey on Drug Use and Health: National Findings. Office of Applied Studies, Rockville, MD, NSDUH Series H-34, DHHS Publication No. SMA 08-4343.
29. Varlinskaya EI, Spear LP (2002) Acute effects of ethanol on social behavior of adolescent and adult rats: role of familiarity of the test situation. Alcohol Clin Exp Res 26:1502-1511.
30. Varlinskaya EI, Spear LP (2008) Social interactions in adolescent and adult Sprague-Dawley rats: impact of social deprivation and test context familiarity. Behav Brain Res 188:398-405.
31. Vetter CS, Doremus-Fitzwater TL, Spear LP (2007) Time course of elevated ethanol intake in adolescent relative to adult rats under continuous, voluntary-access conditions. Alcohol Clin Exp Res 31:1159-1168.
32. Vetter-O'Hagen CS, Spear LP (2012) Hormonal and physical markers of puberty and their relationship to adolescent-typical novelty-directed behavior. Dev Psychobiol 54:523-535.
33. White AM, Truesdale MC, Bae JG, Ahmad S, Wilson WA, Best PJ, Swartzwelder HS (2002) Differential effects of ethanol on motor coordination in adolescent and adult rats. Pharmacol Biochem Behav 73:673-677.
34. Wilkinson JL, Li C, Bevins RA (2009) Pavlovian drug discrimination with bupropion as a feature positive occasion setter: substitution by methamphetamine and nicotine, but not cocaine. Addict Biol 14:165-173.
35. Zorrilla EP (1997) Multiparous species present problems (and possibilities) to developmentalists. Dev Psychobiol 30:141-150.