Toll-like receptor signaling regulates cisplatin-induced mechanical allodynia in mice

Cancer Chemotherapy and Pharmacology

Volumn 73, Issue 1, 2014, Pages 25-34

  Park, Hue Jung ^a   Stokes, Jennifer A ^b   Corr, Maripat ^c   Yaksh, Tony L ^b  

^a The Catholic University of Korea   (South Korea)

^b University of California at San Diego   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Allodynia; Cisplatin; Dorsal root ganglion; Mouse; Toll like receptor

Indexed keywords

CISPLATIN; TOLL LIKE RECEPTOR;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; MALE; MOUSE; NEUROPATHY; NONHUMAN; PRIORITY JOURNAL; SPINAL GANGLION; WEIGHT REDUCTION;

EID: 84892782735     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-013-2304-9     Document Type: Article

References (40)

1. Trigg ME, Higa GM (2010) Chemotherapy-induced nausea and vomiting: antiemetic trials that impacted clinical practice. J Oncol Pharm Pract 16(4):233-244. doi: 10.1177/1078155209354655
2. Windebank AJ, Grisold W (2008) Chemotherapy-induced neuropathy. J Peripher Nerv Syst 13(1):27-46. doi: 10.1111/j.1529-8027.2008.00156.x
3. McKeage MJ (1995) Comparative adverse effect profiles of platinum drugs. Drug Saf 13(4):228-244
4. Park SB, Krishnan AV, Lin CS, Goldstein D, Friedlander M, Kiernan MC (2008) Mechanisms underlying chemotherapy-induced neurotoxicity and the potential for neuroprotective strategies. Curr Med Chem 15(29):3081-3094
5. Park HJ, Stokes JA, Pirie E, Skahen J, Shtaerman Y, Yaksh TL (2013) Persistent hyperalgesia in the cisplatin-treated mouse as defined by threshold measures, the conditioned place preference paradigm, and changes in dorsal root ganglia activated transcription factor 3: the effects of gabapentin, ketorolac, and etanercept. Anesth Analg 116(1):224-231. doi: 10.1213/ANE.0b013e31826e1007
6. Peters CM, Jimenez-Andrade JM, Kuskowski MA, Ghilardi JR, Mantyh PW (2007) An evolving cellular pathology occurs in dorsal root ganglia, peripheral nerve and spinal cord following intravenous administration of paclitaxel in the rat. Brain Res 1168:46-59. doi: 10.1016/j.brainres.2007.06.066
7. Hai T, Wolford CC, Chang YS (2010) ATF3, a hub of the cellular adaptive-response network, in the pathogenesis of diseases: is modulation of inflammation a unifying component? Gene Expr 15(1):1-11
8. Kawai T, Akira S (2011) Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 34(5):637-650. doi: 10.1016/j.immuni.2011.05.006
9. O'Neill LA, Bowie AG (2007) The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7(5):353-364. doi: 10.1038/nri2079
10. Boivin A, Pineau I, Barrette B, Filali M, Vallieres N, Rivest S, Lacroix S (2007) Toll-like receptor signaling is critical for Wallerian degeneration and functional recovery after peripheral nerve injury. J Neurosci 27(46):12565-12576. doi: 10.1523/JNEUROSCI.3027-07.2007
11. Lehnardt S (2010) Innate immunity and neuroinflammation in the CNS: the role of microglia in Toll-like receptor-mediated neuronal injury. Glia 58(3):253-263. doi: 10.1002/glia.20928
12. Liu T, Gao YJ, Ji RR (2012) Emerging role of Toll-like receptors in the control of pain and itch. Neurosci Bull 28(2):131-144. doi: 10.1007/s12264-012- 1219-5
13. Stokes JA, Corr M, Yaksh TL (2013) Spinal Toll-like receptor signaling and nociceptive processing: regulatory balance between TIRAP and TRIF cascades mediated by TNF and IFNbeta. Pain. doi: 10.1016/j.pain.2013.01.012
14. Vera G, Chiarlone A, Martin MI, Abalo R (2006) Altered feeding behaviour induced by long-term cisplatin in rats. Auton Neurosci 126-127:81-92. doi: 10.1016/j.autneu.2006.02.011
15. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL (1994) Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 53(1):55-63. doi: 10.1016/0165-0270(94)90144-9
16. Abalo R, Cabezos PA, Vera G, Lopez-Perez AE, Martin MI (2013) Cannabinoids may worsen gastric dysmotility induced by chronic cisplatin in the rat. Neurogastroenterol Motil 25 (5):373-382, e292. doi: 10.1111/nmo.12073
17. Jack CS, Arbour N, Manusow J, Montgrain V, Blain M, McCrea E, Shapiro A, Antel JP (2005) TLR signaling tailors innate immune responses in human microglia and astrocytes. J Immunol 175(7):4320-4330. http://www.jimmunol.org/content/ 175/7/4320
18. Qi J, Buzas K, Fan H, Cohen JI, Wang K, Mont E, Klinman D, Oppenheim JJ, Howard OM (2011) Painful pathways induced by TLR stimulation of dorsal root ganglion neurons. J Immunol 186(11):6417-6426. doi: 10.4049/jimmunol.1001241
19. Kuang X, Huang Y, Gu HF, Zu XY, Zou WY, Song ZB, Guo QL (2012) Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats. Eur J Pharmacol 676(1-3):51-56. doi: 10.1016/j.ejphar.2011.11.037
20. Hai T, Hartman MG (2001) The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis. Gene 273(1):1-11. doi: 10.1016/S0378-1119(01)00551-0
21. Ivanavicius SP, Ball AD, Heapy CG, Westwood FR, Murray F, Read SJ (2007) Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation. Pain 128(3):272-282. doi: 10.1016/j.pain.2006.12.022
22. Jimenez-Andrade JM, Peters CM, Mejia NA, Ghilardi JR, Kuskowski MA, Mantyh PW (2006) Sensory neurons and their supporting cells located in the trigeminal, thoracic and lumbar ganglia differentially express markers of injury following intravenous administration of paclitaxel in the rat. Neurosci Lett 405(1-2):62-67. doi: 10.1016/j.neulet.2006.06.043
23. Khasabova IA, Khasabov S, Paz J, Harding-Rose C, Simone DA, Seybold VS (2012) Cannabinoid type-1 receptor reduces pain and neurotoxicity produced by chemotherapy. J Neurosci 32(20):7091-7101. doi: 10.1523/JNEUROSCI.0403-12.2012
24. Braz JM, Basbaum AI (2010) Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli. Pain 150(2):290-301. doi: 10.1016/j.pain.2010.05.005
25. Cao H, Zhang YQ (2008) Spinal glial activation contributes to pathological pain states. Neurosci Biobehav Rev 32(5):972-983. doi: 10.1016/j.neubiorev.2008.03.009
26. Sung YJ, Chiu DT, Ambron RT (2006) Activation and retrograde transport of protein kinase G in rat nociceptive neurons after nerve injury and inflammation. Neuroscience 141(2):697-709. doi: 10.1016/j.neuroscience.2006.04. 033
27. Cavassani KA, Ishii M, Wen H, Schaller MA, Lincoln PM, Lukacs NW, Hogaboam CM, Kunkel SL (2008) TLR3 is an endogenous sensor of tissue necrosis during acute inflammatory events. J Exp Med 205(11):2609-2621. doi: 10.1084/jem.20081370
28. Erridge C (2010) Endogenous ligands of TLR2 and TLR4: agonists or assistants? J Leukoc Biol 87(6):989-999. doi: 10.1189/jlb.1209775
29. Marsh BJ, Williams-Karnesky RL, Stenzel-Poore MP (2009) Toll-like receptor signaling in endogenous neuroprotection and stroke. Neuroscience 158(3):1007-1020. doi: 10.1016/j.neuroscience.2008.07.067
30. Rivest S (2009) Regulation of innate immune responses in the brain. Nat Rev Immunol 9(6):429-439. doi: 10.1038/nri2565
31. Shichita T, Hasegawa E, Kimura A, Morita R, Sakaguchi R, Takada I, Sekiya T, Ooboshi H, Kitazono T, Yanagawa T, Ishii T, Takahashi H, Mori S, Nishibori M, Kuroda K, Akira S, Miyake K, Yoshimura A (2012) Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain. Nat Med 18(6):911-917. doi: 10.1038/nm.2749
32. Stewart CR, Stuart LM, Wilkinson K, van Gils JM, Deng J, Halle A, Rayner KJ, Boyer L, Zhong R, Frazier WA, Lacy-Hulbert A, El Khoury J, Golenbock DT, Moore KJ (2010) CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat Immunol 11(2):155-161. doi: 10.1038/ni.1836
33. Yanai H, Ban T, Wang Z, Choi MK, Kawamura T, Negishi H, Nakasato M, Lu Y, Hangai S, Koshiba R, Savitsky D, Ronfani L, Akira S, Bianchi ME, Honda K, Tamura T, Kodama T, Taniguchi T (2009) HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses. Nature 462(7269):99-103. doi: 10.1038/nature08512
34. Zhang J, Takahashi HK, Liu K, Wake H, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M (2011) Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats. Stroke 42(5):1420-1428. doi: 10.1161/STROKEAHA.110.598334
35. Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, Junger W, Brohi K, Itagaki K, Hauser CJ (2010) Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 464(7285):104-107. doi: 10.1038/nature08780
36. Shibasaki M, Sasaki M, Miura M, Mizukoshi K, Ueno H, Hashimoto S, Tanaka Y, Amaya F (2010) Induction of high mobility group box-1 in dorsal root ganglion contributes to pain hypersensitivity after peripheral nerve injury. Pain 149(3):514-521. doi: 10.1016/j.pain.2010.03.023
37. Badary OA, Awad AS, Sherief MA, Hamada FM (2006) In vitro and in vivo effects of ferulic acid on gastrointestinal motility: inhibition of cisplatin-induced delay in gastric emptying in rats. World J Gastroenterol 12(33):5363-5367
38. Isambert N, Fumoleau P, Paul C, Ferrand C, Zanetta S, Bauer J, Ragot K, Lizard G, Jeannin JF, Bardou M (2013) Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors. BMC Cancer 13:172. doi: 10.1186/1471-2407-13-172
39. Sussman DA, Santaolalla R, Strobel S, Dheer R, Abreu MT (2012) Cancer in inflammatory bowel disease: lessons from animal models. Curr Opin Gastroenterol 28(4):327-333. doi: 10.1097/MOG.0b013e328354cc36
40. Biron CA (2001) Interferons alpha and beta as immune regulators-a new look. Immunity 14(6):661-664. doi: 10.1016/S1074-7613(01)00154-6