Tissue-based microarray expression of genes predictive of metastasis in uveal melanoma and differentially expressed in metastatic uveal melanoma

Journal of Ophthalmic and Vision Research

Volumn 8, Issue 4, 2013, Pages 303-307

  Demirci, Hakan ^a   Reed, David ^a   Elner, Victor M ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Cancer; Eye; Gene expression profiling; Melanoma; Metastasis; Microarray; Uvea

Indexed keywords

EID: 84892736641     PISSN: 20082010     EISSN: 2008322X     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Lorigan JG, Wallace S, Mavligit GM. The prevalence and location of metastases from ocular melanoma: imaging study in 110 patients. AJR Am J Roentgenol 1991;157:1279-1281
2. Borthwick NJ, Thombs J, Polak M, Gabriel FG, Hungerford JL, Damato B, et al. The biology of micrometastases from uveal melanoma. J Clin Pathol 2011;64:666-671
3. Eskelin S, Pyrhonen S, Summanen P, Hahka- Kemppinen M, Kivela T. Tumor doubling times in metastatic malignant melanoma of the uvea: tumor progression before and after treatment. Ophthalmology 2000;107:1443-1449
4. Horodenski J. Studies on the presence of free cells of malignant melanoma of the uvea in peripheral blood. Klin Oczna 1969;39:407-412
5. Fernandes BF, Belfort RN, Di Cesare S, Burnier MN Jr. Circulating uveal melanoma cells: should we test for them? Can J Ophthalmol 2008;43;155-158
6. Tobal K, Sherman LS, Foss AJ, Lightman SL. Detection of melanocytes from uveal melanoma in peripheral blood using the polymerase chain reaction. Invest Ophthalmol Vis Sci 1993;34:2622-2625
7. El-Shabrawi Y, Langmann G, Hutter H, Kenner L, Hoefler G. Comparison of current methods and PCR for the diagnosis of metastatic disease in uveal malignant melanoma. Ophthalmologica 1998;212:80
8. Boldin I, Langmann G, Richtig E, Schwantzer G, Ardjomand N, Wegscheider B, et al. Fiveyear results of prognostic value of tyrosinase in peripheral blood of uveal melanoma patients. Melanoma Res 2005;15:503-507
9. Keilholz U, Goldin-Lang P, Bechrakis NE, Max N, Letsch A, Schmittel A, et al. Quantitative detection of circulating tumor cells in cutaneous and ocular melanoma and quality assessment by real-time reverse transcriptase-polymerase chain reaction. Clin Cancer Res 2004;10:1605-1612
10. Callejo SA, Antecka E, Blanco PL, Edelstein C, Burnier MN Jr. Identification of circulating malignant cells and its correlation with prognostic factors and treatment in uveal melanoma. A prospective longitudinal study. Eye (Lond) 2007;21:752-759
11. Schuster R, Bechrakis NE, Stroux A, Busse A, Schmittel A, Scheibenbogen C, et al. Circulating tumor cells as prognostic factor for distant metastases and survival in patients with primary uveal melanoma. Clin Cancer Res 2007;13:1171-1178
12. Ulmer A, Beutel J, Süsskind D, Hilgers RD, Ziemssen F, Lüke M, et al. Visualization of circulating melanoma cells in peripheral blood of patients with primary uveal melanoma. Clin Cancer Res 2008;14:4469-4474
13. Suesskind D, Ulmer A, Schiebel U, Fierlbeck G, Spitzer B, Spitzer MS, et al. Circulating melanoma cells in peripheral blood of patients with uveal melanoma before and after different therapies and association with prognostic parameters: a pilot study. Acta Opthalmol 2011;89:17-24
14. Eide N, Faye RS, Høifødt HK, Øvergaard R, Jebsen P, Kvalheim G, et al. Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients. Acta Ophthalmol 2009;87:830-836
15. Foss AJ, Guille MJ, Occleston NL, Hykin PG, Hungerford JL, Lightman S. The detection of melanoma cells in peripheral blood by reverse transcription-polymerase chain reaction. Br J Cancer 1995;72:155-159
16. Onken MD, Worley LA, Ehlers JP, Harbour JW. Gene expression profiling in uveal melanoma reveals two molecular classes and predicts metastatic death. Cancer Res 2004;64:7205-7209
17. Onken MD, Worley LA, Tuscan MD, Harbour JW. An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma. J Mol Diagn 2010;12:461-468
18. Onken MD, Worley LA, Harbour JW. Association between gene expression profile, proliferation and metastasis in uveal melanoma. Curr Eye Res 2010;35:857-863
19. Chang SH, Worley LA, Onken MD, Harbour JW. Prognostic biomarkers in uveal maelanoma: evidence fro a stem cell-like phenotype associated with metastasis. Melanoma Res 2008;18:191-200
20. Meir T, Dror R, Yu X, Qian J, Simon I, Pe'er J, et al. Molecular characteristics of liver metastases from uveal melanoma. Invest Ophthalmol Vis Sci 2007;48:4890-4896
21. Topcu-Yilmaz P, Kiratli H, Saglam A, Soylemezoglu F, Hascelik G. Correlation of clinicopathological parameters with HGF, c-Met, EGFR, and IGF- 1R expression in uveal melanoma. Melanoma Res 2010;20:126-132
22. All-Ericsson C, Girnita L, Seregard S, Bartolazzi A, Jager MJ, Larsson O. Insulin-like growth factor-1 receptor in uveal melanoma: a predictor for metastatic disease and a potential therapeutic target. Invest Ophthalmol Vis Sci 2002;43:1-8
23. Mallikarjuna K, Pushparaj V, Biswas J, Krishnakumar S. Expression of insulin-like growth factor receptor (IGF-1R), c-Fos, and c-Jun in uveal melanoma: an immunohistochemical study. Curr Eye Res 2006;31:875-883
24. Stelzer G, Dalah I, Stein TI, Satanower Y, Rosen N, Nativ N, et al. In-silico human genomics with GeneCards. Human Genomics 2011;5:709-717.