Human airway epithelial cell cultures for modeling Respiratory syncytial virus infection

Current Topics in Microbiology and Immunology

Volumn 372, Issue , 2013, Pages 371-387

  Pickles, Raymond J ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RESPIRATORY SYNCYTIAL VIRUS VACCINE;

ARTICLE; BODY REGIONS; CELL COMPOSITION; CELL CULTURE; CELL STRUCTURE; CILIATED EPITHELIUM; COLUMNAR EPITHELIUM; DEPOLARIZATION; DISEASE MODEL; DISEASE SEVERITY; DONOR; DRUG DEVELOPMENT; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SPECIES COMPARISON; VACCINATION; VIRAL TROPISM; VIROGENESIS; VIRUS PATHOGENESIS;

ANIMALS; CELL POLARITY; CELLS, CULTURED; CILIA; CYTOKINES; EPITHELIAL CELLS; HOST SPECIFICITY; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, BIOLOGICAL; RESPIRATORY MUCOSA; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; VIRUS REPLICATION;

EID: 84892704563     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-38919-1_19     Document Type: Article

References (31)

1. Bartlett EJ, Cruz AM, Esker J, Castano A, Schomacker H, Surman SR, Hennessey M, Boonyaratanakornkit J, Pickles RJ, Collins PL, Murphy BR, Schmidt AC (2008a) Human parainfluenza virus type 1 C proteins are nonessential proteins that inhibit the host interferon and apoptotic responses and are required for efficient replication in nonhuman primates. J Virol 82(18):8965-8977
2. Bartlett EJ, Hennessey M, Skiadopoulos MH, Schmidt AC, Collins PL, Murphy BR, Pickles RJ (2008b) Role of interferon in the replication of human parainfluenza virus type 1 wild type and mutant viruses in human ciliated airway epithelium. J Virol 82(16):8059-8070
3. Bove PF, Grubb BR, Okada SF, Ribeiro CM, Rogers TD, Randell SH, O'Neal WK, Boucher RC (2011) Human alveolar type II cells secrete and absorb liquid in response to local nucleotide signaling. J Biol Chem 285(45):34939-34949
4. Button B, Cai LH, Ehre C, Kesimer M, Hill DB, Sheehan JK, Boucher RC, Rubinstein M (2012) A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science 337(6097):937-941
5. Collins PL (1990) O glycosylation of glycoprotein G of human respiratory syncytial virus is specified within the divergent ectodomain. J Virol 64(8):4007-4012
6. Fulcher ML, Gabriel S, Burns KA, Yankaskas JR, Randell SH (2005) Well-differentiated human airway epithelial cell cultures. Methods Mol Med 107:183-206
7. Fulcher ML, Gabriel SE, Olsen JC, Tatreau JR, Gentzsch M, Livanos E, Saavedra MT, Salmon P, Randell SH (2009) Novel human bronchial epithelial cell lines for cystic fibrosis research. Am J Physiol Lung Cell Mol Physiol 296(1):L82-L91
8. Harkema J, Mariassy A, St. George J, Hyde DM, Plopper CG (1994) Epithelial cells of the conducting airways: a species comparison. In: Farmer SG, Hay DWP (eds) The airway epithelium, vol 505. Lung Biology in Health and Disease. Marcel Dekker, New York, pp 3-39
9. Ilyushina NA, Ikizler MR, Kawaoka Y, Rudenko LG, Treanor JJ, Subbarao K, Wright PF (2012) Comparative study of influenza virus replication in MDCK cells and in primary cells derived from adenoids and airway epithelium. J Virol
10. Johnson JE, Gonzales RA, Olson SJ, Wright PF, Graham BS (2007) The histopathology of fatal untreated human respiratory syncytial virus infection. Mod Pathol 20(1):108-119
11. Karron RA, Buonagurio DA, Georgiu AF, Whitehead SS, Adamus JE, Clements-Mann ML, Harris DO, Randolph VB, Udem SA, Murphy BR, Sidhu MS (1997) Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant. Proc Natl Acad Sci USA 94(25):13961-13966
12. Kesimer M, Ehre C, Burns KA, Davis CW, Sheehan JK, Pickles RJ (2012) Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways. Mucosal Immunol
13. Kesimer M, Kirkham S, Pickles RJ, Henderson AG, Alexis NE, Demaria G, Knight D, Thornton DJ, Sheehan JK (2009) Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? Am J Physiol Lung Cell Mol Physiol 296(1):L92-L100
14. Kwilas S, Liesman RM, Zhang L, Walsh E, Pickles RJ, Peeples ME (2009) Respiratory syncytial virus grown in Vero cells contains a truncated attachment protein that alters its infectivity and dependence on glycosaminoglycans. J Virol 83(20):10710-10718
15. Matrosovich MN, Matrosovich TY, Gray T, Roberts NA, Klenk HD (2004) Human and avian influenza viruses target different cell types in cultures of human airway epithelium. Proc Natl Acad Sci USA 101(13):4620-4624
16. Neilson KA, Yunis EJ (1990) Demonstration of respiratory syncytial virus in an autopsy series. Pediatr Pathol 10(4):491-502
17. Pickles RJ, McCarty D, Matsui H, Hart PJ, Randell SH, Boucher RC (1998) Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer. J Virol 72(7):6014-6023
18. Schaap-Nutt A, Scull MA, Schmidt AC, Murphy BR, Pickles RJ (2010) Growth restriction of an experimental live attenuated human parainfluenza virus type 2 vaccine in human ciliated airway epithelium in vitro parallels attenuation in African green monkeys. Vaccine 28(15):2788-2798
19. Schaap-Nutt A, Liesman R, Bartlett EJ, Scull MA, Collins PL, Pickles RJ, Schmidt AC (2012) Human parainfluenza virus serotypes differ in their kinetics of replication and cytokine secretion in human tracheobronchial airway epithelium. Virology 433(2):320-328
20. Scull MA, Gillim-Ross L, Santos C, Roberts KL, Bordonali E, Subbarao K, Barclay WS, Pickles RJ (2009) Avian Influenza virus glycoproteins restrict virus replication and spread through human airway epithelium at temperatures of the proximal airways. PLoS Pathog 5(5):e1000424
21. Sims AC, Baric RS, Yount B, Burkett SE, Collins PL, Pickles RJ (2005) Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs. J Virol 79(24):15511-15524
22. Sims AC, Yount B, Burkett SE, Baric RS, Pickles RJ (2006) SARS CoV replication and pathogenesis in human airway epithelial cultures. Adv Exp Med Biol 581:535-538
23. Stonebraker JR, Wagner D, Lefensty RW, Burns K, Gendler SJ, Bergelson JM, Boucher RC, O'Neal WK, Pickles RJ (2004) Glycocalyx restricts adenoviral vector access to apical receptors expressed on respiratory epithelium in vitro and in vivo: role for tethered mucins as barriers to lumenal infection. J Virol 78(24):13755-13768
24. Villenave R, Thavagnanam S, Sarlang S, Parker J, Douglas I, Skibinski G, Heaney LG, McKaigue JP, Coyle PV, Shields MD, Power UF (2012) In vitro modeling of respiratory syncytial virus infection of pediatric bronchial epithelium, the primary target of infection in vivo. Proc Natl Acad Sci USA 109(13):5040-5045
25. Welliver TP, Reed JL, Welliver RC Sr (2008) Respiratory syncytial virus and influenza virus infections: observations from tissues of fatal infant cases. Pediatr Infect Dis J 27(10 Suppl):S92-S96
26. Wright PF, Ikizler MR, Gonzales RA, Carroll KN, Johnson JE, Werkhaven JA (2005) Growth of respiratory syncytial virus in primary epithelial cells from the human respiratory tract. J Virol 79(13):8651-8654
27. Zabner J, Seiler M, Walters R, Kotin RM, Fulgeras W, Davidson BL, Chiorini JA (2000) Adeno-associated virus type 5(AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer. J Virol 74 (8):3852-3858
28. Zhang L, Bukreyev A, Thompson CI, Watson B, Peeples ME, Collins PL, Pickles RJ (2005) Infection of ciliated cells by human parainfluenza virus type 3 in an in vitro model of human airway epithelium. J Virol 79(2):1113-1124
29. Zhang L, Button B, Gabriel SE, Burkett S, Yan Y, Skiadopoulos MH, Dang YL, Vogel LN, McKay T, Mengos A, Boucher RC, Collins PL, Pickles RJ (2009) CFTR delivery to 25 % of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium. PLoS Biol 7(7):e1000155
30. Zhang L, Collins PL, Lamb RA, Pickles RJ (2012) Comparison of differing cytopathic effects in human airway epithelium of parainfluenza virus 5(W3A), parainfluenza virus type 3, and respiratory syncytial virus. Virology 421 (1):67-77
31. Zhang L, Peeples ME, Boucher RC, Collins PL, Pickles RJ (2002) Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. J Virol 76(11):5654-5666