Synthesis of new potent agonistic analogs of growth hormone-releasing hormone (GHRH) and evaluation of their endocrine and cardiac activities

Peptides

Volumn 52, Issue , 2014, Pages 104-112

  Cai, Renzhi ^a,b   Schally, Andrew V ^a,b   Cui, Tengjiao ^a,b   Szalontay, Luca ^a   Halmos, Gabor ^a,b,d   Sha, Wei ^a,b,c   Kovacs, Magdolna ^a,b,e   Jaszberenyi, Miklos ^a,f   He, Jinlin ^a   Rick, Ferenc G ^a,b   Popovics, Petra ^a,b   Kanashiro Takeuchi, Rosemeire ^b,c   Hare, Joshua M ^b   Block, Norman L ^a,b   Zarandi, Marta ^a,b,f  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^d UNIVERSITY OF DEBRECEN   (Hungary)

^e UNIVERSITY OF PÉCS   (Hungary)

^f UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Cardioprotection; hGHRH agonist; hGHRH(1 29); s.c. administration

Indexed keywords

GROWTH HORMONE RELEASING FACTOR DERIVATIVE; GROWTH HORMONE RELEASING HORMONE AGONIST; HORMONE RECEPTOR STIMULATING AGENT; JI 38; MR 326; MR 327; MR 351; MR 356; MR 361; MR 367; MR 401; MR 403; MR 404; MR 405; MR 406; MR 407; MR 408; MR 409; MR 410; MR 420; MR 421; MR 502; MR 504; MR 702; PLACEBO; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENDOCRINE FUNCTION; EXPERIMENTAL MYOCARDIAL INFARCTION; FEMALE; GROWTH HORMONE RELEASE; HEART FUNCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

CARDIOPROTECTION; HGHRH AGONIST; HGHRH(1-29); S.C. ADMINISTRATION;

AGMATINE; ANIMALS; ENDOCRINE SYSTEM; GROWTH HORMONE-RELEASING HORMONE; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84892692521     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2013.12.010     Document Type: Article

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