Serratia marcescens in a neonatal intensive care unit: Two long-term multiclone outbreaks in a 10-year observational study

New Microbiologica

Volumn 36, Issue 4, 2013, Pages 373-383

  Casolari, Chiara ^a   Pecorari, Monica ^a   Della Casa, Elisa ^b   Cattani, Silvia ^b   Venturelli, Claudia ^a   Fabio, Giuliana ^a   Tagliazucchi, Sara ^a   Serpini, Giulia Fregni ^a   Migaldi, Mario ^a   Marchegiano, Patrizia ^b   Rumpianesi, Fabio ^a   Ferrari, Fabrizio ^b  

^a Department of Integrated Activity of Laboratory Medicine ^*  (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Molecular epidemiology; Neonatal intensive care unit; Outbreak; Serratia marcescens

Indexed keywords

EID: 84892687849     PISSN: 11217138     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. ARSLAN U., ERAYMAN I., YUKSEKKAYA S., CIMEN O., TUNCER I., BOZDOGAN B. (2010). Serratia marcescens sepsis outbreak in a neonatal intensive care unit. Pediatr. Int. 52, 208-212.
2. ASSADIAN O., BERGER A., ASPOCK C., MUSTAFA S., KOHLHAUSER C., HIRSCHL A.M. (2002). Nosocomial outbreak of Serratia marcescens in a neonatal intensive care unit. Infect. Control Hosp. Epidemiol. 23, 457-461.
3. BAYRAMOGLU G., BURUK K., DINC U., MUTLU M., YLMAZ G., ASLAN Y. (2011). Investigation of an outbreak of Serratia marcescens in a neonatal intensive care unit. J. Microbiol. Imunol. Infect. 44, 111-115.
4. BIZZARRO M.J., DEMBRY L.M., BALTIMORE R.S., GALLAGHER P.G. (2007). Case-control analysis of endemic Serratia marcescens bacteremia in a neonatal intensive care unit. Arch. Dis. Child Fetal Neonatal. 92, 120-126.
5. BOSI C., DAVIN-REGLI A., CHARREL R., ROCCA B., MONNET D., BOLLET C. (1996). Serratia marcescens nosoco-mial outbreak due to contamination of hexetidine solution. J. Hosp. Infect. 33, 217-224.
6. BUFFET-BATAILLON S., RABIER V., BÉTRÉMIEUX P., BEUCHÉE A., BAUER M., PLADYS P., ET AL. (2009). Outbreak of Serratia marcescens in a neonatal intensive care unit: contaminated unmedicated liquid soap and risk factors. J. Hosp. Infect. 72, 17-22.
7. CARROLL K.C., WEINSTEIN M.P. (2007). Manual and automated system for detection and identification of microorganisms. In: Murray PR, Baron EJ, Landry ML, Jorgensen JH, Pfaller MA, editors. Manual of clinical microbiology. 9th ed. Washington: ASM Press. 192-217.
8. CIMOLAI N., TROMBLEY C., WENSLEY D., LE BLANC J. (1997). Heterogeneous Serratia marcescens genotypes from a nosocomial pediatric outbreak. Chest. 111, 194-197.
9. CIVEN R., VUGIA D.J., ALEXANDER R., BRUNNER W., TAYLOR S., PARRIS N., ET AL (2006). Outbreak of Serratia marcescens infections following injection of betamethasone compounded at a community pharmacy. Clin. Infect. Dis. 43, 831-837.
10. CRIVARO V., BAGATTINI M., SALZA M.F., RAIMONDI F., ROSSANO F., TRIASSI M., ET AL (2007). Risk factors for extendet-spectrum β-lactamase-producing Serratia marcescens and Klebsiella pneumoniae acquisition in a neonatal intensive care unit. J. Hosp. Infect. 67, 135-141.
11. CULLEN M.M., TRAIL A., ROBINSON M., KEANEY M., CHADWICK P.R. (2005). Serratia marcescens outbreak in a neonatal intensive care unit prompting review of decontamination of laryngoscopes. J. Hosp. Infect. 59, 68-70.
12. DAVID M.D., WELLER T.M.A., LAMBERT P., FRAISE A.P. (2006). An outbreak of Serratia marcescens on the neonatal unit: a tale of two clones. J. Hosp. Infect. 63, 27-33.
13. ENCISO-MORENO J.A., PERNAS-BUITRON N., ORTIZ-HERRERA M., CORIA-JIMENEZ R. (2004). Identification of Serratia marcescens populations of nosocomial origin by RAPD-PCR. Arch. Med. Res. 35, 12-17.
14. FLEISCH F., ZIMMERMANN-BAER U., ZBINDEN R., BISHOFF G., ARLETTAZ R., VALDVOGEL K., ET AL (2002). Three consecutive outbreaks of Serratia marcescens in a neonatal intensive care unit. Clin. Infect. Dis. 34, 767-773.
15. FRIEDMAN N.D., KOTSANAS D., BRETT G., BILLAH B., KORMAN T.M. (2008). Investigation of an outbreak of Serratia marcescens in a neonatal unit via a case-control study and molecular typing. Am. J. Infect. Control. 36, 22-28.
16. GILES M., HARWOOD H.M., GOSLING D.A., HENNESSY D., PEARCE C.T., DALEY A.J. (2006). What is the best screening method to detect Serratia marcescens colonization during an outbreak in a neonatal intensive care nursery? J. Hosp. Infect. 62, 349-352.
17. GILLESPIE E.E., BRADFORD J., BRETT J., KOTSANAS D. (2007). Serratia marcescens bacteremia-an indicator for outbreak management and heightened surveillance. J. Perinat. Med. 35, 227-231.
18. HEJAZI A., FALKINER F.R. (1997). Serratia marcescens. J. Med. Microbiol. 46, 903-912.
19. HEJAZI A., KEANE C.T., FALKINER F.R. (1997). The use of RAPD-PCR as a typing method for Serratia marcescens. J. Med. Microbiol. 46, 913-919.
20. JANG T.N., FUNG C.P., YANG T.L., SHEN S.H., HUANG C.S., LEE S.H. (2001). Use of pulsed-field gel elec-trophoresis to investigate an outbreak of Serratia marcescens infection in a neonatal intensive care unit. J. Hosp. Infect. 48, 13-19.
21. LIGOZZI M., FONTANA R., ALDEGHERI M., SCALET G., LO CASCIO G. (2010). Comparative evaluation of an automated repetitive-sequence-based PCR instrument versus pulsed-field gel electrophoresis in the setting of a Serratia marcescens nosocomial infection outbreak. J. Clin. Microbiol. 48, 1690-1695.
22. MADANI T.A., ALSAEDI S., JAMES L., ELDEEK B.S., JIMAN-FATANI A.A., ALAWI M.M., ET AL (2011). Serratia marcescens-contaminated baby shampoo causing an outbreak among newborns at King Abdulaziz University Hospita, Jeddah, Saudi Arabia. J. Hosp. Infect. 78, 16-19.
23. MALTEZU H.C., TRYFINOPOULOU K., KATERELOS P., FTIKA L., PAPPA O., TSERONI M., ET AL (2012). Consecutive Serratia marcescens multiclone outbreaks in neonatal intensive care unit. Am. J. Infect. Control. 40, 637-642.
24. MANNING M.L., ARCHIBALD L.K., BELL L.M., BANERIJEE S.N., JARVIS W.R. (2001). Serratia marcescens transmission in a pediatric intensive care unit: a multi-factorial occurrence. Am. J. Infect. Control. 29, 115-119.
25. MARAGAKIS L.L., WINKLER A., TUCKER M.G., COSGROVE S.E., ROSS T., LAWSON E. ET AL. (2008). Outbreak of multidrug-resistant Serratia marcescens infection in a neonatal intensive care unit. Infect. Control Hosp. Epidemiol. 29, 418-423.
26. MILISAVLJEVIC V., WU F., LARSON E., RUBENSTEIN D., ROSS B., DRUSIN L.M., ET AL (2004). Molecular epidemiology of Serratia marcescens outbreaks in two neonatal intensive care units. Infect Control Hosp. Epidemiol. 25, 719-721.
27. MIRANDA G., KELLY C., SOLORZANO F., LEANOS B., CORIA R., PATTERSON J.E. (1996). Use of pulsed-field gel electrophoresis typing to study an outbreak of infection due to Serratia marcescens in a neonatal intensive care unit. J. Clin. Microbiol. 34, 3138-3141.
28. MIRANDA-NOVALES G., LEANOS B., DIAZ-RAMOS R., GONZALES-TEJEDA L., PEREGRINO-BEJARANO L., VILLEGAS-SILVA R., ET AL (2003). An outbreak due to Serratia marcescens in a neonatal intensive care unit typed by 2-day pulsed field gel electrophoresis protocol. Arch. Med. Res. 34, 237-241.
29. PARVAZ P., TILLE D., MEUGNIER H., PERRAUD M., CHEVALLIER P., RITTER J., ET AL (2002). A rapid and easy PCR-RFLP method for genotyping Serratia marcescens strains isolated in different hospital outbreaks and patient environments in the Lyon area, France. J. Hosp. Infect. 51, 96-105.
30. PEROTTI G., BERNARDO M.E., SPALLA M., MATTI A., STRONATI M., PAGANI L. (2007). Rapid control of two outbreaks of Serratia marcescens in a Northern Italian neonatal intensive care unit. J. Chemoter. 19, 56-60.
31. POLILLI E., PARRUTI G., FAZII P., D'ANTONIO D., PALMIERI D., D'INCECCO C., ET AL. (2011). Rapidly controller out break of Serratia marcescens infection/colonisations in a neonatal intensive care unit, Pescara General Hospital, Pescara, Italy. Euro Surveill. 16, pii 19892.
32. PRASAD G.A., JONES P.G., MICHAELS J., GARLAND J.S., SHIVPURI C.R. (2001). Outbreak of Serratia marcescens infection in a neonatal intensive care unit. Infect. Control Hosp. Epidemiol. 22, 303-305.
33. RABIER V., BATAILLON S., JOLIVET-GOUGEON A., CHAPPLAIN J.M., BEUCHÉE A., BÉTRÉMIEUX P. (2008). Hand washing soap as a source of neonatal Serratia marcescens outbreak. Acta Pediatr. 97, 1381-1385.
34. SARTOR C., JACOMO V., DUVIVIER C., TISSOT-DUPONT H., SAMBUS R., DRANC M. (2000). Nosocomial Serratia marcescens infections associated with extrinsic contamination of a liquid nonmedicated soap. Infect. Control Hosp. Epidemiol. 21, 196-199.
35. SARVIKIVI E., LYYTIKAINEN O., SALMENLINNA S., VUOPIO-VARKILA J., LUUKKAINEN P., TARKKA E. ET AL. (2004). Clustering of Serratia marcescens infections in a neonatal intensive care unit. Infect. Control Hosp. Epidemiol. 25, 723-729.
36. STEPPBERGER K., WALTER S., CLAROS M.C., SPENCKER F.B., KIESS W., RODLOF A.C., ET AL (2002). Nosocomial neonatal outbreak of Serratia marcescens: analysis of pathogens by pulsed field gel electrophoresis and polymerase chain reaction. Infection. 30, 277-281.
37. VILLARI P., CRISPINO M., SALVADORI A., SCARCELLA A. (2001). Molecular epidemiology of an outbreak of Serratia marcescens in a neonatal intensive care unit. Infect. Control Hosp. Epidemiol. 22, 630-634.
38. VOELZ A., MULLER A., GILLEN J., DRESBACH T., ENGHELHART S., BATES C.J., ET AL (2010). Outbreaks of Serratia marcescensin neonatal and pediatric intensive care units: clinical aspects, risk factors and management. Int. J. Hyg. Environ. Health. 213, 79-87.