Placental gene expression patterns of endoglin (CD105) in intrauterine growth restriction

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 27, Issue 4, 2014, Pages 350-354

  Szentpéteri, Imre ^a   Rab, Attila ^b   Kornya, László ^c   Kovács, Péter ^d   Brubel, Réka ^e   Joó, József Gábor ^e  

^a Praxis für Gynäkologie und Geburtshilfe und Allgemeine Medizin ^*  (Germany)

^b Hospital Telki   (Hungary)

^c Saint Stephen Hospital   (Hungary)

^d Clinical Research Unit Hungary   (Hungary)

^e SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Angiogenesis; Antiangiogenic activity; Endoglin; Gene expression; Intrauterine growth restriction; Placenta

Indexed keywords

BETA ACTIN; ENDOGLIN; BIOLOGICAL MARKER; CELL SURFACE RECEPTOR; ENG PROTEIN, HUMAN; LEUKOCYTE ANTIGEN;

ADULT; ARTICLE; BIRTH WEIGHT; BODY MASS; CONTROLLED STUDY; DISEASE SEVERITY; ENDOGLIN GENE; FEMALE; FETUS; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; INTRAUTERINE GROWTH RETARDATION; MAJOR CLINICAL STUDY; MALE; NEWBORN; NUCLEOTIDE SEQUENCE; PLACENTA; PRIORITY JOURNAL; SEX DIFFERENCE; WEIGHT GAIN; CASE CONTROL STUDY; GENETICS; METABOLISM; PREGNANCY; REAL TIME POLYMERASE CHAIN REACTION; STATISTICAL MODEL; UPREGULATION; WESTERN BLOTTING;

ADULT; ANTIGENS, CD; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CASE-CONTROL STUDIES; FEMALE; FETAL GROWTH RETARDATION; HUMANS; LOGISTIC MODELS; MALE; PLACENTA; PREGNANCY; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CELL SURFACE; SEX FACTORS; UP-REGULATION;

EID: 84892687758     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2013.818125     Document Type: Article

References (29)

1. Wollmann HA. Intrauterine growth restriction: definition and etiology. Horm Res 1988;49:1-6.
2. Marconi AM, Cetin I, Davoli E, et al. An evaluation of fetal glucogenesis in intrauterine growth-retarded pregnancies. Metabolism 1993;42:860-4.
3. Magnusson AL, Powell T, Wennergren M, et al. Glucose metabolism in the human preterm and term placenta of IUGR fetuses. Placenta 2004;25:337-46.
4. Economides DL, Nicolaides KH. Blood glucose and oxygen tension levels in small-for-gestational-age fetuses. Am J Obstet Gynecol 1989;160:385-9.
5. Sheikh S, Satoskar P, Bhartiya D. Expression of insulin-like growth factor-I and placental growth hormone mRNA in placentae: a comparison between normal and intrauterine growth retardation pregnancies. Mol Hum Reprod 2001;7:287-92.
6. Gluckman PD, Harding JE. The physiology and pathophysiology of intrauterine growth retardation. Horm Res 1997;48:11-16.
7. Maulik D, Frances Evans J, Ragolia L. Fetal growth restriction: pathogenic mechanisms. Clin Obstet Gynecol 2006;49:219-2.
8. Arroyo JA, Winn VD. Vasculogenesis and angiogenesis in the IUGR placenta. Semin Perinatol 2008;32:172-7.
9. Ahmed A, Perkins J. Angiogenesis and intrauterine growth restriction. Baillieres Best Pract Res Clin Obstet Gynaecol 2000; 14:981-98.
10. Pardi G, Marconi AM, Cetin I. Pathophysiology of intrauterine growth retardation: role of the placenta. Acta Paediatr Suppl 1997; 423:170-2.
11. Demir R, Seval Y, Huppertz B. Vasculogenesis and angiogenesis in the early human placenta. Acta Histochem 2007;109:257-65.
12. Mayhew TM, Charnock-Jones DS, Kaufmann P. Aspects of human fetoplacental vasculogenesis and angiogenesis. III. Changes in complicated pregnancies. Placenta 2004;25:127-39.
13. Gougos A, Letarte M. Primary structure of endoglin; an RDGconatining glycoprotein of human endothelial cells. J Biol Chem 1990;265:8361-4.
14. Ten Dijke P, Goumans M, Pardali E. Endoglin in angiogenesis and vascular diseases. Angiogenesis 2008;11:79-89.
15. Van Laake LW, van den Driesche S, Post S, et al. Endoglin has a crucial role in blood cell-mediated vascular repair. Circulation 2006;114:2288-97.
16. Zhang Y, Yang Y, Hong H. Multimodality molecular imaging of CD105 (endoglin) expression. Int J Clin Exp Med 2011;4:32-42.
17. Ten Dijke P, Arthur HM. Extracellular controll of TGF-beta signalling in vascular development and disease. Nat Rev Mol Cell Biol 2007;8:857-69.
18. Arthur HM, Ure J, Smith AJ, et al. Endoglin, an ancillary TGF-beta receptor, is rerquired for extraembryonic angiogenesis and plays a key role in heart development. Dev Biol 2000;217:42-53.
19. Yinon Y, Kingdom JCP, Odutayo A, et al. Vascular dysfunction in women with a history of preeclampsia and intrauterine growth restriction. Circulation 2010;122:1846-53.
20. Wallner W, Sengenberger R, Strick R, et al. Angiogenetic growth factors in maternal and fetal serum in pregnancies complicated by intrauterine growth restriction. Clin Sci 2007;112:51-7.
21. Asvold BO, Vatten LJ, Romundstad PR, et al. Angiogenic factors in maternal circulation and the risk of severe fetal growth restriction. Am J Epidemiol 2011;173:630-9.
22. Laskowska M, Laskowska K, Oleszczuk J. Endoglin in pregnancy complicated by fetal intrauterine growth restriction in normotensive and preeclamptic pregnant women: a comparison between preeclamptic patients with appropriate-for-gestational-age weight infants and heatlhy pregnant women. J Mat Fet Neonat Med 2012;25:806-81.
23. Ramsay JE, Ferrell WR, Crawford L, et al. Divergent metabolic and vascular phenotypes in preeclampsia and intrauterine growth restriction. J Hypertens 2004;22:2177-83.
24. Stepan H, Kramer T, Faber R. Maternal plasma concentrations of soluble endoglin in pregnancies with intrauterine growth restriction. J Clin Endocrin Metab 2007;92:2831-4.
25. Yinon Y, Nevo O, Xu J, et al. Severe intrauterine growth restriction pregnancies have increased placental endoglin levels. Am J Path 2008;172:77-85.
26. Jeyabalan A, McGonigal S, Gilmour C, et al. Circulating and placental endoglin concentrations in pregnancies complicated by intrauterine growth restriction and preeclampsia. Placenta 2008;29: 555-63.
27. Szentpéteri I, Rab A, Kornya L, et al. Gene expression patterns of vascular endothelial growth factor (VEGF-A) in human placenta from pregnancies with intrauterine growth restriction. J Mat Fet Neonat Med 2013;26:984-989.
28. Chen CP, Bajoria R, Aplin JD. Decreased vascularization and cell proliferation in placentas of intrauterine growth-restricted fetuses with abnormal umbilical artery flow velocity waveforms. Am J Obstet Gynecol 2002;187:764-9.
29. Elhawary TM, El-Bandary AS, Demerdash H. Maternal serum endoglin as an early marker of preeclampsia in high risk patients. Int J Women Health 2012;4:521-5.