Detection of tissue factor antigen and coagulation activity in coronary artery thrombi isolated from patients with ST-segment elevation acute myocardial infarction

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Palmerini, Tullio ^a   Tomasi, Luciana ^a   Barozzi, Chiara ^a   Della Riva, Diego ^a   Mariani, Andrea ^a   Taglieri, Nevio ^a   Leone, Ornella ^a   Ceccarelli, Claudio ^a   De Servi, Stefano ^b   Branzi, Angelo ^a   Genereux, Philippe ^c   Stone, Gregg W ^c   Ahamed, Jasimuddin ^d  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Ospedale Civile   (Italy)

^c Department of Medicine   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 5G9; THROMBOPLASTIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ASPIRATION CATHETER; BLOOD CLOTTING; BLOOD CLOTTING TIME; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY THROMBOSIS; ERYTHROCYTE; FEMALE; GENERAL DEVICE; HISTOPATHOLOGY; HOMOGENIZER; HUMAN; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INFLAMMATORY CELL; MALE; MONOCYTE; NEUTROPHIL; OPTICAL INSTRUMENTATION; PATIENT REFERRAL; PERCUTANEOUS CORONARY INTERVENTION; PROTHROMBIN TIME; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; THROMBECTOMY DEVICE; THROMBOCYTE AGGREGATION; THROMBUS ASPIRATION;

AGED; CORONARY THROMBOSIS; CORONARY VESSELS; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; THROMBOPLASTIN;

EID: 84892624415     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081501     Document Type: Article

References (34)

1. Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, et al. (2011) Heart disease and stroke statistics-2012 update: a report from the american heart association. Circulation 125: e2-e220.
2. Jackson SP (2011) Arterial thrombosis-insidious, unpredictable and deadly. Nat Med 17: 1423-1436.
3. Badimon JJ, Lettino M, Toschi V, Fuster V, Berrozpe M, et al. (1999) Local inhibition of tissue factor reduces the thrombogenicity of disrupted human atherosclerotic plaques: effects of tissue factor pathway inhibitor on plaque thrombogenicity under flow conditions. Circulation 99: 1780-1787.
4. Marmur JD, Thiruvikraman SV, Fyfe BS, Guha A, Sharma SK, et al. (1996) Identification of active tissue factor in human coronary atheroma. Circulation 94: 1226-1232.
5. Toschi V, Gallo R, Lettino M, Fallon JT, Gertz SD, et al. (1997) Tissue factor modulates the thrombogenicity of human atherosclerotic plaques. Circulation 95: 594-599.
6. Norledge BV, Petrovan RJ, Ruf W, Olson AJ (2003) The tissue factor/factor VIIa/factor Xa complex: a model built by docking and site-directed mutagenesis. Proteins 53: 640-648.
7. Belting M, Ahamed J, Ruf W (2005) Signaling of the tissue factor coagulation pathway in angiogenesis and cancer. Arterioscler Thromb Vasc Biol 25: 1545-1550.
8. Ruf W, Rehemtulla A, Edgington TS (1991) Antibody mapping of tissue factor implicates two different exon-encoded regions in function. Biochem J 278 (Pt 3): 729-733.
9. Drake TA, Morrissey JH, Edgington TS (1989) Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis. Am J Pathol 134: 1087-1097.
10. Tremoli E, Camera M, Toschi V, Colli S (1999) Tissue factor in atherosclerosis. Atherosclerosis 144: 273-283.
11. Annex BH, Denning SM, Channon KM, Sketch MH Jr, Stack RS, et al. (1995) Differential expression of tissue factor protein in directional atherectomy specimens from patients with stable and unstable coronary syndromes. Circulation 91: 619-622.
12. Ardissino D, Merlini PA, Ariens R, Coppola R, Bramucci E, et al. (1997) Tissuefactor antigen and activity in human coronary atherosclerotic plaques. Lancet 349: 769-771.
13. Ahamed J, Ruf W (2004) Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem 279: 23038-23044.
14. Riewald M, Ruf W (2001) Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor. Proc Natl Acad Sci U S A 98: 7742-7747.
15. Huang M, Syed R, Stura EA, Stone MJ, Stefanko RS, et al. (1998) The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. J Mol Biol 275: 873-894.
16. Ahamed J, Versteeg HH, Kerver M, Chen VM, Mueller BM, et al. (2006) Disulfide isomerization switches tissue factor from coagulation to cell signaling. Proc Natl Acad Sci U S A 103: 13932-13937.
17. Palmerini T, Nedelman MA, Scudder LE, Nakada MT, Jordan RE, et al. (2002) Effects of abciximab on the acute pathology of blood vessels after arterial stenting in nonhuman primates. J Am Coll Cardiol 40: 360-366.
18. Hoshiba Y, Hatakeyama K, Tanabe T, Asada Y, Goto S (2006) Co-localization of von Willebrand factor with platelet thrombi, tissue factor and platelets with fibrin, and consistent presence of inflammatory cells in coronary thrombi obtained by an aspiration device from patients with acute myocardial infarction. J Thromb Haemost 4: 114-120.
19. Sakai T, Inoue S, Takei M, Ogawa G, Hamazaki Y, et al. (2011) Activated inflammatory cells participate in thrombus size through tissue factor and plasminogen activator inhibitor-1 in acute coronary syndrome: Immunohisto-chemical analysis. Thromb Res 127: 443-449.
20. Balasubramanian V, Grabowski E, Bini A, Nemerson Y (2002) Platelets, circulating tissue factor, and fibrin colocalize in ex vivo thrombi: real-time fluorescence images of thrombus formation and propagation under defined flow conditions. Blood 100: 2787-2792.
21. Balasubramanian V, Vele O, Nemerson Y (2002) Local shear conditions and platelet aggregates regulate the incorporation and activity of circulating tissue factor in ex-vivo thrombi. Thromb Haemost 88: 822-826.
22. Giesen PL, Rauch U, Bohrmann B, Kling D, Roque M, et al. (1999) Blood-borne tissue factor: another view of thrombosis. Proc Natl Acad Sci U S A 96: 2311-2315.
23. Hoffman M, Whinna HC, Monroe DM (2006) Circulating tissue factor accumulates in thrombi, but not in hemostatic plugs. J Thromb Haemost 4: 2092-2093.
24. Palmerini T, Coller BS, Cervi V, Tomasi L, Marzocchi A, et al. (2004) Monocyte-derived tissue factor contributes to stent thrombosis in an in vitro system. J Am Coll Cardiol 44: 1570-1577.
25. Owens AP 3rd, Mackman N (2011) Microparticles in hemostasis and thrombosis. Circ Res 108: 1284-1297.
26. Rauch U, Bonderman D, Bohrmann B, Badimon JJ, Himber J, et al. (2000) Transfer of tissue factor from leukocytes to platelets is mediated by CD15 and tissue factor. Blood 96: 170-175.
27. Camera M, Brambilla M, Facchinetti L, Canzano P, Spirito R, et al. (2011) Tissue Factor and Atherosclerosis: Not only vessel wall-derived TF, but also platelet-associated TF. Thromb Res 129: 279-284.
28. Camera M, Brambilla M, Toschi V, Tremoli E (2010) Tissue factor expression on platelets is a dynamic event. Blood 116: 5076-5077.
29. Camera M, Frigerio M, Toschi V, Brambilla M, Rossi F, et al. (2003) Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs. Arterioscler Thromb Vasc Biol 23: 1690-1696.
30. Mackman N (2009) The many faces of tissue factor. J Thromb Haemost 7 Suppl 1: 136-139.
31. Loubele ST, Spek CA, Leenders P, van Oerle R, Aberson HL, et al. (2009) Active site inhibited factor VIIa attenuates myocardial ischemia/reperfusion injury in mice. J Thromb Haemost 7: 290-298.
32. Palmerini T, Biondi-Zoccai G, Della Riva D, Mariani A, Sabate M, et al. (2013) Clinical Outcomes With Drug-Eluting and Bare-Metal Stents in Patients With ST-Segment Elevation Myocardial Infarction: Evidence From a Comprehensive Network Meta-Analysis. J Am Coll Cardiol 62: 496-504.
33. Wallentin L, Becker RC, Budaj A, Cannon CP, Emanuelsson H, et al. (2009) Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 361: 1045-1057.
34. Wiviott SD, Braunwald E, McCabe CH, Montalescot G, Ruzyllo W, et al. (2007) Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 357: 2001-2015.