Synthesis of the 2-methylene analogue of the HRV 3C protease inhibitor thysanone (2-carbathysanone)

Organic and Biomolecular Chemistry

Volumn 12, Issue 6, 2014, Pages 905-912

  Schünemann, Katrin ^a   Furkert, Daniel P ^a   Choi, Eun Cho ^a   Connelly, Stephen ^b   Fraser, John D ^a   Sperry, Jonathan ^a   Brimble, Margaret A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POSITIVE IONS;

2-METHYLENE; BIOLOGICAL EVALUATION; COMMON COLD; HUMAN RHINOVIRUS; NATURAL PRODUCTS; PROTEASE ACTIVITIES; PROTEASE INHIBITOR; STRUCTURAL FEATURE;

CHEMISTRY;

3C PROTEASES; BENZOPYRAN DERIVATIVE; CYSTEINE PROTEINASE; NAPHTHOQUINONE; PROTEINASE INHIBITOR; THYSANONE; VIRUS PROTEIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; METABOLISM; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BENZOPYRANS; CYSTEINE ENDOPEPTIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; MOLECULAR STRUCTURE; NAPHTHOQUINONES; PROTEASE INHIBITORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; VIRAL PROTEINS;

EID: 84892619596     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c3ob41951g     Document Type: Article

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