Spontaneous reactivation of hepatitis B virus replication in an HIV coinfected patient with isolated anti-Hepatitis B core antibodies

Virology Journal

Volumn 11, Issue 1, 2014, Pages

  Pei, Rongjuan ^a,b   Grund, Sebastian ^c   Verheyen, Jens ^b   Esser, Stefan ^b   Chen, Xinwen ^a   Lu, Mengji ^a,b  

^a WUHAN INSTITUTE OF VIROLOGY   (China)

^b UNIVERSITY HOSPITAL ESSEN   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Anti HBc only; HBV; HIV; Mutation; Reactivation

Indexed keywords

ANTIVIRAL AGENTS; COINFECTION; DNA, VIRAL; HEPATITIS B ANTIBODIES; HEPATITIS B CORE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; MUTANT PROTEINS; MUTATION, MISSENSE; VIRAL LOAD; VIRUS ACTIVATION;

EID: 84892616835     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-11-9     Document Type: Article

References (33)

1. Epidemiology of viral hepatitis and HIV co-infection. Alter MJ, J Hepatol 2006 44 6 S9 16352363
2. The influence of human immunodeficiency virus type 1 infection on the development of the hepatitis B virus carrier state. Bodsworth NJ, Cooper DA, Donovan B, J Infect Dis 1991 163 1138 1140 10.1093/infdis/163.5.1138 2019762
3. Reactivation of hepatitis B in AIDS. Vento S, Di Perri G, Garofano T, Concia E, Bassetti D, Lancet 1989 2 108 109
4. Reactivation of hepatitis B. Hoofnagle JH, Hepatology 2009 49 156 S165 10.1002/hep.22945 19399803
5. Frequency of hepatitis B virus reactivation in cancer patients undergoing cytotoxic chemotherapy: a prospective study of 626 patients with identification of risk factors. Yeo W, Chan PK, Zhong S, Ho WM, Steinberg JL, Tam JS, Hui P, Leung NW, Zee B, Johnson PJ, J Med Virol 2000 62 299 307 10.1002/1096- 9071(200011)62:3<299::AID-JMV1>3.0.CO;2-0 11055239
6. Chronic hepatitis B reactivation following infliximab therapy in Crohn's disease patients: need for primary prophylaxis. Esteve M, Saro C, Gonzalez-Huix F, Suarez F, Forne M, Viver JM, Gut 2004 53 1363 1365 10.1136/gut.2004.040675 15306601 (Pubitemid 39120128)
7. Redevelopment of hepatitis B surface antigen after renal transplantation. Marcellin P, Giostra E, Martinot-Peignoux M, Loriot MA, Jaegle ML, Wolf P, Degott C, Degos F, Benhamou JP, Gastroenterology 1991 100 1432 1434 2013388
8. Hepatitis B reactivation after withdrawal of pre-emptive lamivudine in patients with haematological malignancy on completion of cytotoxic chemotherapy. Hui CK, Cheung WW, Au WY, Lie AK, Zhang HY, Yueng YH, Wong BC, Leung N, Kwong YL, Liang R, Lau GK, Gut 2005 54 1597 1603 10.1136/gut.2005.070763 16000641 (Pubitemid 41531779)
9. Nucleotide sequence analysis of the precore region in patients with spontaneous reactivation of chronic hepatitis B. Laskus T, Rakela J, Tong MJ, Persing DH, Dig Dis Sci 1994 39 2000 2006 10.1007/BF02088138 8082510 (Pubitemid 24306085)
10. Reactivation of hepatitis B in a long-term anti-HBs-positive patient with AIDS following lamivudine withdrawal. Altfeld M, Rockstroh JK, Addo M, Kupfer B, Pult I, Will H, Spengler U, J Hepatol 1998 29 306 309 10.1016/S0168-8278(98) 80017-2 9722213 (Pubitemid 28352817)
11. Hepatitis B exacerbation with a precore mutant virus following withdrawal of lamivudine in a human immunodeficiency virus-infected patient. Neau D, Schvoerer E, Robert D, Dubois F, Dutronc H, Fleury HJ, Ragnaud JM, J Infect 2000 41 192 194 10.1053/jinf.2000.0724 11023772
12. Probable corticosteroid-induced reactivation of latent hepatitis B virus infection in an HIV-positive patient involving immune escape. Martel N, Cotte L, Trabaud MA, Trepo C, Zoulim F, Gomes SA, Kay A, J Infect Dis 2012 205 1757 1761 10.1093/infdis/jis268 22459735
13. Molecular analysis of hepatitis B virus (HBV) in an HIV co-infected patient with reactivation of occult HBV infection following discontinuation of lamivudine-including antiretroviral therapy. Costantini A, Marinelli K, Biagioni G, Monachetti A, Ferreri ML, Butini L, Montroni M, Manzin A, Bagnarelli P, BMC Infect Dis 2011 11 310 10.1186/1471-2334-11-310 22054111
14. Symptomatic hepatitis B virus (HBV) reactivation despite reduced viral fitness is associated with HBV test and immune escape mutations in an HIV-coinfected patient. Henke-Gendo C, Amini-Bavil-Olyaee S, Challapalli D, Trautwein C, Deppe H, Schulz TF, Heim A, Tacke F, J Infect Dis 2008 198 1620 1624 10.1086/592987 18847320
15. Serological pattern "anti-HBc alone": report on a workshop. Grob P, Jilg W, Bornhak H, Gerken G, Gerlich W, Gunther S, Hess G, Hudig H, Kitchen A, Margolis H, et al. J Med Virol 2000 62 450 455 10.1002/1096- 9071(200012)62:4<450::AID-JMV9>3.0.CO;2-Y 11074473
16. The significance of 'anti-HBc only' in the clinical virology laboratory. Alhababi F, Sallam TA, Tong CY, J Clin Virol 2003 27 162 169 10.1016/S1386-6532(02)00171-3 12829038 (Pubitemid 37329337)
17. The underlying mechanisms for the 'anti-HBc alone' serological profile. Ponde RA, Cardoso DD, Ferro MO, Arch Virol 2010 155 149 158 10.1007/s00705-009- 0559-6 20091193
18. Clinical significance of "anti-HBc alone" in human immunodeficiency virus-positive patients. Perez-Rodriguez MT, Sopena B, Crespo M, Rivera A, Gonzalez Del Blanco T, Ocampo A, Martinez-Vazquez C, World J Gastroenterol 2009 15 1237 1241 10.3748/wjg.15.1237 19291824
19. High frequency of HCV infection in individuals with isolated antibody to hepatitis B core antigen. Berger A, Doerr HW, Rabenau HF, Weber B, Intervirology 2000 43 71 76 10.1159/000025026 10971123
20. Serological pattern "anti-HBc alone": characterization of 552 individuals and clinical significance. Knoll A, Hartmann A, Hamoshi H, Weislmaier K, Jilg W, World J Gastroenterol 2006 12 1255 1260 16534880
21. Isolated antibody to hepatitis B core antigen in human immunodeficiency virus type-1-infected individuals. Gandhi RT, Wurcel A, Lee H, McGovern B, Boczanowski M, Gerwin R, Corcoran CP, Szczepiorkowski Z, Toner S, Cohen DE, et al. Clin Infect Dis 2003 36 1602 1605 10.1086/375084 12802762 (Pubitemid 36783346)
22. Reactivation of hepatitis B in an HIV-infected patient with antibodies against hepatitis B core antigen as the only serological marker. Chamorro AJ, Casado JL, Bellido D, Moreno S, Eur J Clin Microbiol Infect Dis 2005 24 492 494 10.1007/s10096-005-1355-1 15990987 (Pubitemid 41124504)
23. Molecular, immunological and clinical properties of mutated hepatitis B viruses. Kreutz C, J Cell Mol Med 2002 6 113 143 10.1111/j.1582-4934.2002. tb00317.x 12003675 (Pubitemid 44133989)
24. Molecular epidemiology of hepatitis B virus vaccine variants in Singapore. Oon CJ, Lim GK, Ye Z, Goh KT, Tan KL, Yo SL, Hopes E, Harrison TJ, Zuckerman AJ, Vaccine 1995 13 699 702 10.1016/0264-410X(94)00080-7 7483783
25. Evolution of hepatitis B virus sequence from a liver transplant recipient with rapid breakthrough despite hepatitis B immune globulin prophylaxis and lamivudine therapy. Kim KH, Lee KH, Chang HY, Ahn SH, Tong S, Yoon YJ, Seong BL, Kim SI, Han KH, J Med Virol 2003 71 367 375 10.1002/jmv.10503 12966541 (Pubitemid 37176625)
26. Vaccine-induced escape mutant of hepatitis B virus. Carman WF, Zanetti AR, Karayiannis P, Waters J, Manzillo G, Tanzi E, Zuckerman AJ, Thomas HC, Lancet 1990 336 325 329 10.1016/0140-6736(90)91874-A 1697396 (Pubitemid 20264145)
27. Coexistence of hepatitis B surface antigen (HBsAg) and heterologous subtype-specific antibodies to HBsAg among patients with chronic hepatitis B virus infection. Zhang JM, Xu Y, Wang XY, Yin YK, Wu XH, Weng XH, Lu M, Clin Infect Dis 2007 44 1161 1169 10.1086/513200 17407033 (Pubitemid 46651239)
28. High genetic variability of the group-specific a-determinant of hepatitis B virus surface antigen (HBsAg) and the corresponding fragment of the viral polymerase in chronic virus carriers lacking detectable HBsAg in serum. Weinberger KM, Bauer T, Bohm S, Jilg W, J Gen Virol 2000 81 1165 1174 10769057 (Pubitemid 30232700)
29. Spontaneous reactivation in chronic hepatitis B: patterns and natural history. Gupta S, Govindarajan S, Fong TL, Redeker AG, J Clin Gastroenterol 1990 12 562 568 10.1097/00004836-199010000-00015 2230000 (Pubitemid 20303420)
30. Monitoring the natural course and response to therapy of chronic hepatitis B with an automated semi-quantitative assay for IgM anti-HBc. Brunetto MR, Cerenzia MT, Oliveri F, Piantino P, Randone A, Calvo PL, Manzini P, Rocca G, Galli C, Bonino F, J Hepatol 1993 19 431 436 10.1016/S0168-8278(05)80554-9 7512111 (Pubitemid 24029922)
31. Radiation-induced hepatitis B virus reactivation in liver mediated by the bystander effect from irradiated endothelial cells. Chou CH, Chen PJ, Lee PH, Cheng AL, Hsu HC, Cheng JC, Clin Cancer Res 2007 13 851 857 10.1158/1078-0432. CCR-06-2459 17289877 (Pubitemid 46340359)
32. Reactivation of hepatitis B virus associated with chemotherapy and immunosuppressive agent. Wijaya I, Hasan I, Acta Med Indones 2013 45 61 66 23585411
33. Synergistic effect of radiation and interleukin-6 on hepatitis B virus reactivation in liver through STAT3 signaling pathway. Chou CH, Chen PJ, Jeng YM, Cheng AL, Huang LR, Cheng JC, Int J Radiat Oncol Biol Phys 2009 75 1545 1552 10.1016/j.ijrobp.2008.12.072 19327909