Human L-ficolin, a recognition molecule of the lectin activation pathway of complement, activates complement by binding to pneumolysin, the major toxin of Streptococcus pneumoniae

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Ali, Youssif M ^a,b   Kenawy, Hany I ^a,b   Muhammad, Adnan ^a   Sim, Robert B ^a   Andrew, Peter W ^a   Schwaeble, Wilhelm J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b University of Mansoura   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; FICOLIN; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN M; PNEUMOLYSIN;

ANTIGEN ANTIBODY COMPLEX; ARTICLE; BINDING ASSAY; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; COMPLEMENT SYSTEM; CONTROLLED STUDY; HUMAN; IN VITRO STUDY; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; OPSONIZATION; PROTEIN BINDING; PROTEIN CLEAVAGE; STREPTOCOCCUS PNEUMONIAE; WESTERN BLOTTING;

ADULT; BACTERIAL PROTEINS; COMPLEMENT ACTIVATION; COMPLEMENT C1Q; COMPLEMENT C3; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; COMPLEMENT SYSTEM PROTEINS; HUMANS; LECTINS; PROTEIN BINDING; RECOMBINANT PROTEINS; STREPTOLYSINS;

EID: 84892607888     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0082583     Document Type: Article

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