Complex mixtures of antibodies generated from a single production qualitatively and quantitatively evaluated by native Orbitrap mass spectrometry

mAbs

Volumn 6, Issue 1, 2014, Pages 197-203

  Thompson, Natalie J ^a,b   Hendriks, Linda J A ^c   De Kruif, John ^c   Throsby, Mark ^c   Heck, Albert J R ^a,b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NETHERLANDS PROTEOMICS CENTRE   (Netherlands)

^c Merus BV   (Netherlands)

Author keywords

Composite mixtures; High resolution mass spectrometry; Intact protein analysis; Monoclonal antibody; Native mass spectrometry

Indexed keywords

MONOCLONAL ANTIBODY;

ACCURACY; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ANTIBODY SCREENING; ARTICLE; DRUG MIXTURE; MASS SPECTROMETRY; OPTICAL RESOLUTION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REPRODUCIBILITY;

HEK293 CELLS; HUMANS; MASS SPECTROMETRY; SINGLE-CHAIN ANTIBODIES;

EID: 84892601242     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.27126     Document Type: Article

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